Zobrazeno 1 - 10
of 14
pro vyhledávání: '"B. Rhodes Ford"'
Autor:
B. Rhodes Ford, Amanda C. Poholek
Publikováno v:
The Journal of Immunology. 210:869-879
Exhaustion is a state of CD8 T cell differentiation that occurs in settings of chronic Ag such as tumors, chronic viral infection, and autoimmunity. Cellular differentiation is driven by a series of environmental signals that promote epigenetic lands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48cd55a96f67443c30924ad8f8de9b90
https://doi.org/10.4049/jimmunol.2200681
https://doi.org/10.4049/jimmunol.2200681
Autor:
Paolo D. A. Vignali, Kristin DePeaux, McLane J. Watson, Chenxian Ye, B. Rhodes Ford, Konstantinos Lontos, Nicole K. McGaa, Nicole E. Scharping, Ashley V. Menk, Simon C. Robson, Amanda C. Poholek, Dayana B. Rivadeneira, Greg M. Delgoffe
Publikováno v:
Nature Immunology. 24:267-279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5b04dd1f0b003240dcd0422a4fb8079
https://doi.org/10.1038/s41590-022-01379-9
https://doi.org/10.1038/s41590-022-01379-9
Autor:
B. Rhodes Ford, Paolo D. A. Vignali, Natalie L. Rittenhouse, Nicole E. Scharping, Ronal Peralta, Konstantinos Lontos, Andrew T. Frisch, Greg M. Delgoffe, Amanda C. Poholek
Publikováno v:
Sci Immunol
Response rates to immunotherapy in solid tumors remain low due in part to the elevated prevalence of terminally exhausted T cells, a hypofunctional differentiation state induced through persistent antigen and stress signaling. However, the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b08924bb4f05a2d0d80de6a93062a38
https://europepmc.org/articles/PMC9851604/
https://europepmc.org/articles/PMC9851604/
Autor:
Ashley V. Menk, Dayana Rivadeneira, Natalie Rittenhouse, Yiyang Wang, Kristin DePeaux, Amanda C. Poholek, Ronal Peralta, Yupeng Wang, Nicole E. Scharping, Paolo Vignali, Greg M. Delgoffe, B. Rhodes Ford
Publikováno v:
Nature Immunology. 22:205-215
Cancer and chronic infections induce T cell exhaustion, a hypofunctional fate carrying distinct epigenetic, transcriptomic and metabolic characteristics. However, drivers of exhaustion remain poorly understood. As intratumoral exhausted T cells exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54c830c5a95c00f877cc113fce715ed4
https://doi.org/10.1038/s41590-020-00834-9
https://doi.org/10.1038/s41590-020-00834-9
Autor:
Corry D. Bondi, Roderick J. Tan, Ora A. Weisz, Cary R. Boyd-Shiwarski, B. Rhodes Ford, Amanda C. Poholek, Youssef Rbaibi, Kimberly R. Long, Joseph Locker
Publikováno v:
Am J Physiol Renal Physiol
The multiligand receptors megalin (Lrp2) and cubilin (Cubn) and their endocytic adaptor protein Dab2 (Dab2) play essential roles in maintaining the integrity of the apical endocytic pathway of proximal tubule (PT) cells and have complex and poorly un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7872b7ba7755a1d017fb02227965a3
https://europepmc.org/articles/PMC8698540/
https://europepmc.org/articles/PMC8698540/
Publikováno v:
The Journal of Immunology. 206:94.15-94.15
Blimp-1 is a transcription factor known to have critical roles in multiple cell types including B, T and NK cells. However, its expression and function in non-NK innate lymphoid cell populations have not been well studied. To examine the expression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a8ba2e31e9522de2d8d972816e52c28
https://doi.org/10.4049/jimmunol.206.supp.94.15
https://doi.org/10.4049/jimmunol.206.supp.94.15
Autor:
Andrew Getahun, B Rhodes Ford, Peter A. Gottlieb, John C. Cambier, Marynette Rihanek, Brianne M. Coleman, Virginia D. Sarapura, Mia J. Smith
Publikováno v:
JCI insight. 4(3)
It has been reported that 2.5%–30% of human peripheral CD27(–) B cells are autoreactive and anergic based on unresponsiveness to antigen receptor (BCR) stimulation and autoreactivity of cloned and expressed BCR. The molecular mechanisms that main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad24b0f0b42d21c126cf80b7a11196fa
https://pubmed.ncbi.nlm.nih.gov/30728334
https://pubmed.ncbi.nlm.nih.gov/30728334
Autor:
Xie, Yifan1,2 (AUTHOR), Xie, Feng3 (AUTHOR), Zhang, Lei4 (AUTHOR), Zhou, Xiaoxue5 (AUTHOR), Huang, Jun5 (AUTHOR), Wang, Fangwei5 (AUTHOR), Jin, Jin5 (AUTHOR), Zhang, Long5 (AUTHOR) l_zhang@zju.edu.cn, Zeng, Linghui1 (AUTHOR) zenglh@zucc.edu.cn, Zhou, Fangfang3 (AUTHOR) zhoufangfang@suda.edu.cn
Publikováno v:
Advanced Science. 11/17/2021, Vol. 8 Issue 22, p1-22. 22p.
Autor:
Ford, B. Rhodes, Vignali, Paolo D. A., Rittenhouse, Natalie L., Scharping, Nicole E., Peralta, Ronal, Lontos, Konstantinos, Frisch, Andrew T., Delgoffe, Greg M., Poholek, Amanda C.
Publikováno v:
Science Immunology; 2022, Vol. 7 Issue 74, p1-17, 17p