Zobrazeno 1 - 10
of 161
pro vyhledávání: '"B. R. Santos"'
Publikováno v:
Scientific Electronic Archives, Vol 12, Iss 1, Pp 59-62 (2019)
The objective of this work was to evaluate the effects of cinnamon powder (Cinnamomum verum) as a phytogenic additive on broiler diets. The treatments were applied in a single shed with 32º NO orientation, randomized complete block design (DBC), wit
Externí odkaz:
https://doaj.org/article/017a95a168394adf9845b6e0c4f7d1af
Publikováno v:
Brazilian Journal of Biology, Iss 0 (2017)
Abstract In this study was evaluated the influence of glutamine supplementation on the endogenous content of amino acids, proteins, total phenolics, flavonoids and proanthocyanidins in Bacupari callus. The explants were inoculated in MS medium, MS wi
Externí odkaz:
https://doaj.org/article/57abae00233b495dad8597131a6812ee
Autor:
Shadrack Kibet, Njogu M. Kimani, Syombua S. Mwanza, Cynthia M. Mudalungu, Cleydson B. R. Santos, Chrysantus M. Tanga
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 510 (2024)
Natural products hold immense potential for drug discovery, yet many remain unexplored in vast libraries and databases. In an attempt to fill this gap and meet the growing demand for effective drugs, this study delves into the promising world of ent-
Externí odkaz:
https://doaj.org/article/9aa23da98e3142aaa97b6b985b4abafb
Autor:
Njogu M. Kimani, Charles O. Ochieng, Mike Don Ogutu, Kevin Otieno Yamo, Joab Otieno Onyango, Cleydson B. R. Santos
Publikováno v:
Journal of Xenobiotics, Vol 13, Iss 1, Pp 102-120 (2023)
Compounds from Zanthoxylum chalybeum Engl. were previously reported for inhibitory activities of amylase and glucosidase enzymatic action on starch as a preliminary study toward the establishment of a management strategy against postprandial hypergly
Externí odkaz:
https://doaj.org/article/ccf770dd614c4b919b3eff6bd054bedf
Autor:
Deyse B. Barbosa, Mayra R. do Bomfim, Tiago A. de Oliveira, Alisson M. da Silva, Alex G. Taranto, Jorddy N. Cruz, Paulo B. de Carvalho, Joaquín M. Campos, Cleydson B. R. Santos, Franco H. A. Leite
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1657 (2023)
Alzheimer’s disease causes chronic neurodegeneration and is the leading cause of dementia in the world. The causes of this disease are not fully understood but seem to involve two essential cerebral pathways: cholinergic and amyloid. The simultaneo
Externí odkaz:
https://doaj.org/article/fdd4fbc549674dd0b53eb8d1d2cef958
Autor:
Cleydson B. R. Santos, Cleison C. Lobato, Sirlene S. B. Ota, Rai C. Silva, Renata C. V. S. Bittencourt, Jofre J. S. Freitas, Elenilze F. B. Ferreira, Marília B. Ferreira, Renata C. Silva, Anderson B. De Lima, Joaquín M. Campos, Rosivaldo S. Borges, José A. H. M. Bittencourt
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1584 (2023)
The design, synthesis, and evaluation of novel non-steroidal anti-inflammatory drugs (NSAIDs) with better activity and lower side effects are big challenges today. In this work, two 5-acetamido-2-hydroxy benzoic acid derivatives were proposed, increa
Externí odkaz:
https://doaj.org/article/3c7c83face0f40d4a86f319b8878dae4
Autor:
Lana P. S. Oliveira, Lúcio R. Lima, Luciane B. Silva, Jorddy N. Cruz, Ryan S. Ramos, Luciana S. Lima, Francy M. N. Cardoso, Aderaldo V. Silva, Dália P. Rodrigues, Gabriela S. Rodrigues, Aldo A. Proietti-Junior, Gabriela B. dos Santos, Joaquín M. Campos, Cleydson B. R. Santos
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1430 (2023)
Staphylococcus aureus is a microorganism with high morbidity and mortality due to antibiotic-resistant strains, making the search for new therapeutic options urgent. In this context, computational drug design can facilitate the drug discovery process
Externí odkaz:
https://doaj.org/article/eaffc86f2be74ad7aac4805b3a84ba51
Autor:
Wagner B. R. Santos, Lícia T. S. Pina, Marlange A. de Oliveira, Lucas A. B. O. Santos, Marcus V. A. Batista, Gabriela G. G. Trindade, Marcelo C. Duarte, Jackson R. G. S. Almeida, Lucindo J. Quintans-Júnior, Jullyana S. S. Quintans, Mairim R. Serafini, Henrique D. M. Coutinho, Grażyna Kowalska, Tomasz Baj, Radosław Kowalski, Adriana G. Guimarães
Publikováno v:
Molecules, Vol 28, Iss 11, p 4465 (2023)
Pain is one of the most prevalent and difficult to manage symptoms in cancer patients, and conventional drugs present a range of adverse reactions. The development of β-cyclodextrins (β-CD) complexes has been used to avoid physicochemical and pharm
Externí odkaz:
https://doaj.org/article/d74d91d93d6043f1a74b06b3941bb759
Autor:
Ruan S. Bastos, Lúcio R. de Lima, Moysés F. A. Neto, Maryam, Numan Yousaf, Jorddy N. Cruz, Joaquín M. Campos, Njogu M. Kimani, Ryan S. Ramos, Cleydson B. R. Santos
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8814 (2023)
When an epidemic started in the Chinese city of Wuhan in December 2019, coronavirus was identified as the cause. Infection by the virus occurs through the interaction of viral S protein with the hosts’ angiotensin-converting enzyme 2. By leveraging
Externí odkaz:
https://doaj.org/article/a3e963ad0b864c9c83505e8c7be9a6db
Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach
Autor:
Luciane B. Silva, Elenilze F. B. Ferreira, Maryam, José M. Espejo-Román, Glauber V. Costa, Josiane V. Cruz, Njogu M. Kimani, Josivan S. Costa, José A. H. M. Bittencourt, Jorddy N. Cruz, Joaquín M. Campos, Cleydson B. R. Santos
Publikováno v:
Molecules, Vol 28, Iss 3, p 1035 (2023)
Acetylcholinesterase (AChE) enzymes play an essential role in the development of Alzheimer’s disease (AD). Its excessive activity causes several neuronal problems, particularly psychopathies and neuronal cell death. A bioactive pose on the hAChE B
Externí odkaz:
https://doaj.org/article/dc71a5ccb35141a8b7192fc4f562a8a2