Zobrazeno 1 - 3
of 3
pro vyhledávání: '"B. R. Prashanth Kumar"'
Autor:
Kohji Hizume, Kiran Batta, Chandrima Das, Stephanie Lorain, Tapas K. Kundu, Parag P. Sadhale, Alain Verreault, B. R. Prashanth Kumar, Semanti Ganguly, Shrikanth S. Gadad, Kunio Takeyasu
Publikováno v:
Molecular and Cellular Biology. 26:8303-8315
Human transcriptional coactivator PC4 is a highly abundant multifunctional protein which plays diverse important roles in cellular processes, including transcription, replication, and repair. It is also a unique activator of p53 function. Here we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac061fbfd5170a4f2eb86fcc2f673208
https://doi.org/10.1128/mcb.00887-06
https://doi.org/10.1128/mcb.00887-06
Publikováno v:
Journal of Biological Chemistry. 276:16804-16809
The human positive coactivator 4 (PC4) acts as a general coactivator for activator-dependent transcription, the activity of which is regulated negatively by phosphorylation. We report here that PC4 can be acetylated specifically by another coactivato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3130ac222f03c09462b6bc473b1d9e
https://doi.org/10.1074/jbc.m100934200
https://doi.org/10.1074/jbc.m100934200
The function of p53 is modulated by several transcriptional coactivators that regulate its tumor suppressor activity. Here we report that human transcriptional coactivator PC4 enhances the DNA binding of p53 to its cognate site in vitro and directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421b26dabe15e96047885ae3c7aa59e9
https://europepmc.org/articles/PMC350566/
https://europepmc.org/articles/PMC350566/
