Zobrazeno 1 - 10
of 40
pro vyhledávání: '"B. R. BACON"'
Publikováno v:
Cleveland Clinic Journal of Medicine. 63:264-268
Although progress has been made toward developing a cheap and accurate method to diagnose hepatitis C virus (HCV) infection, current screening tests have an unacceptably high false-positive rate. Newer tests are more accurate, but also more costly. T
Publikováno v:
Alimentary pharmacologytherapeutics. 32(8)
The efficacy of re-treating genotype I hepatitis C virus (HCV) patients who failed combination therapy with interferon/pegylated interferon (PEG-IFN) and ribavirin remains unclear.To quantify sustained virological response (SVR) rates with different
Autor:
B R, Bacon, A M, Di Bisceglie
Publikováno v:
The New England journal of medicine. 345(19)
Autor:
M A, Khan, J E, Poulos, E M, Brunt, L, Li, H, Solomon, R S, Britton, B R, Bacon, A M, Di Bisceglie
Publikováno v:
Hepato-gastroenterology. 48(37)
The mechanism of hepatic fibrogenesis with chronic viral hepatitis is not well understood. Persistent activation of hepatic stellate cells is felt to play a role in the development of fibrogenesis and progression to cirrhosis.We determined the expres
Autor:
G A, Ramm, S C, Carr, K R, Bridle, L, Li, R S, Britton, D H, Crawford, C A, Vogler, B R, Bacon, T F, Tracy
Publikováno v:
Liver. 20(5)
Myofibroblasts are the primary cells responsible for increased matrix deposition in hepatic fibrosis. Activation of hepatic stellate cells and portal fibroblasts to myofibroblasts during cholestatic liver injury is accompanied by increased expression
Autor:
S, Ramrakhiani, B R, Bacon
Publikováno v:
The Medical clinics of North America. 84(5)
The 1990s have been an exciting time for the field of hepatology. There has been a rapid expansion of knowledge, and new discoveries have revolutionized the field. It is now possible to characterize and treat many more liver diseases. Newer medicatio
Publikováno v:
Digestive diseases and sciences. 44(10)
We evaluated the contribution of alcohol abuse to liver failure among patients undergoing liver transplantation by reviewing their records for alcohol consumption, hepatitis serology, and outcome. Anti-HCV was present in the serum of 42 patients (39%
Autor:
R S, Britton, B R, Bacon
Publikováno v:
Alcoholism, clinical and experimental research. 23(5)
Pathological fibrogenesis in the liver is mediated by activated stellate cells. These cells have a myofibroblastic phenotype with the ability to proliferate and synthesize large quantities of extracellular matrix components. A number of factors have
Autor:
B R, Bacon, M L, Schilsky
Publikováno v:
Advances in internal medicine. 44
Discovery of the gene for WD has greatly enhanced our understanding of this disorder at the cellular level and has set the stage for future testing of new modes of therapy. Improvements in analytic methods for detecting mutations in genomic DNA will
Publikováno v:
Hepatology (Baltimore, Md.). 27(4)
The aim of this study was to compare the short-term and long-term efficacy and safety of lymphoblastoid interferon with a recombinant interferon alfa (IFN-alpha) in a 24-week treatment course for chronic hepatitis C. One thousand seventy-one patients