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Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis

Autor: C. CALVO, R. FONTAINE, J. SOUEID, T. TAMMELA, T. MAKINEN, C. ALFARO-CERVELLO, F. BONNAUD, A. MIGUEZ, L. BENHAIM, Y. XU, M. BARALLOBRE, I. MOUTKINE, J. LYYTIKKA, T. TATLISUMAK, B. PYTOWSKI, B. ZALC, W. RICHARDSON, N. KESSARIS, J. GARCIA-VERDUGO, K. ALITALO, A. EICHMANN, J. THOMAS

Publikováno v: GENES & DEVELOPMENT
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)

Neural stem cells (NSCs) are slowly dividing astrocytes that are intimately associated with capillary endothelial cells in the subventricular zone (SVZ) of the brain. Functionally, members of the vascular endothelial growth factor (VEGF) family can s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::28665c9a0a0a8068a81096afb88b9d0a
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2558

Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors

Autor: M, Prewett, J, Huber, Y, Li, A, Santiago, W, O'Connor, K, King, J, Overholser, A, Hooper, B, Pytowski, L, Witte, P, Bohlen, D J, Hicklin

Publikováno v: Cancer research. 59(20)

Tumor angiogenesis is mediated by tumor-secreted angiogenic growth factors that interact with their surface receptors expressed on endothelial cells. Vascular endothelial growth factor (VEGF) and its receptor [fetal liver kinase 1 (Flk-1)/kinase inse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f2ac111716c0e410ac7aa3fbb28c316b
https://pubmed.ncbi.nlm.nih.gov/10537299

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

Autor: L, Witte, D J, Hicklin, Z, Zhu, B, Pytowski, H, Kotanides, P, Rockwell, P, Böhlen

Publikováno v: Cancer metastasis reviews. 17(2)

Biological evidence suggests that interference with the function of the angiogenic growth factor receptor VEGFR2 (flk1/KDR) is a particularly promising strategy to inhibit tumor-induced angiogenesis. Proof of concept was established by developing a m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c63bd0fb92814ef52d1909a5f498b608
https://pubmed.ncbi.nlm.nih.gov/9770111

P-551

Autor: H. Tan, B. Pytowski, Raúl Gómez, Ralf C. Zimmermann, Mark V. Sauer, Nataki C. Douglas

Publikováno v: Fertility and Sterility. 86:S338-S339

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c06d62d417a4925467d306ca6945ea5c
https://doi.org/10.1016/j.fertnstert.2006.07.920