Overview of physics results from MAST upgrade towards core-pedestal-exhaust integration

Autor: J.R. Harrison, A. Aboutaleb, S. Ahmed, M. Aljunid, S.Y. Allan, H. Anand, Y. Andrew, L.C. Appel, A. Ash, J. Ashton, O. Bachmann, M. Barnes, B. Barrett, D. Baver, D. Beckett, J. Bennett, J. Berkery, M. Bernert, W. Boeglin, C. Bowman, J. Bradley, D. Brida, P.K. Browning, D. Brunetti, P. Bryant, J. Bryant, J. Buchanan, N. Bulmer, A. Carruthers, M. Cecconello, Z.P. Chen, J. Clark, C. Cowley, M. Coy, N. Crocker, G. Cunningham, I. Cziegler, T. Da Assuncao, Y. Damizia, P. Davies, I.E. Day, G.L. Derks, S. Dixon, R. Doyle, M. Dreval, M. Dunne, B.P. Duval, T. Eagles, J. Edmond, H. El-Haroun, S.D. Elmore, Y. Enters, M. Faitsch, F. Federici, N. Fedorczak, F. Felici, A.R. Field, M. Fitzgerald, I. Fitzgerald, R. Fitzpatrick, L. Frassinetti, W. Fuller, D. Gahle, J. Galdon-Quiroga, L. Garzotti, S. Gee, T. Gheorghiu, S. Gibson, K.J. Gibson, C. Giroud, D. Greenhouse, V.H. Hall-Chen, C.J. Ham, R. Harrison, S.S. Henderson, C. Hickling, B. Hnat, L. Howlett, J. Hughes, R. Hussain, K. Imada, P. Jacquet, P. Jepson, B. Kandan, I. Katramados, Y.O. Kazakov, D. King, R. King, A. Kirk, M. Knolker, M. Kochan, L. Kogan, B. Kool, M. Kotschenreuther, M. Lees, A.W. Leonard, G. Liddiard, B. Lipschultz, Y.Q. Liu, B.A. Lomanowski, N. Lonigro, J. Lore, J. Lovell, S. Mahajan, F. Maiden, C. Man-Friel, F. Mansfield, S. Marsden, R. Martin, S. Mazzi, R. McAdams, G. McArdle, K.G. McClements, J. McClenaghan, D. McConville, K. McKay, C. McKnight, P. McKnight, A. McLean, B.F. McMillan, A. McShee, J. Measures, N. Mehay, C.A. Michael, F. Militello, D. Morbey, S. Mordijck, D. Moulton, O. Myatra, A.O. Nelson, M. Nicassio, M.G. O’Mullane, H.J.C. Oliver, P. Ollus, T. Osborne, N. Osborne, E. Parr, B. Parry, B.S. Patel, D. Payne, C. Paz-Soldan, A. Phelps, L. Piron, C. Piron, G. Prechel, M. Price, B. Pritchard, R. Proudfoot, H. Reimerdes, T. Rhodes, P. Richardson, J. Riquezes, J.F. Rivero-Rodriguez, C.M. Roach, M. Robson, K. Ronald, E. Rose, P. Ryan, D. Ryan, S. Saarelma, S. Sabbagh, R. Sarwar, P. Saunders, O. Sauter, R. Scannell, T. Schuett, R. Seath, R. Sharma, P. Shi, B. Sieglin, M. Simmonds, J. Smith, A. Smith, V. A. Soukhanovskii, D. Speirs, G. Staebler, R. Stephen, P. Stevenson, J. Stobbs, M. Stott, C. Stroud, C. Tame, C. Theiler, N. Thomas-Davies, A.J. Thornton, M. Tobin, M. Vallar, R.G.L. Vann, L. Velarde, K. Verhaegh, E. Viezzer, C. Vincent, G. Voss, M. Warr, W. Wehner, S. Wiesen, T.A. Wijkamp, D. Wilkins, T. Williams, T. Wilson, H.R. Wilson, H. Wong, M. Wood, V. Zamkovska

Publikováno v: Nuclear Fusion, Vol 64, Iss 11, p 112017 (2024)

Recent results from MAST Upgrade are presented, emphasising understanding the capabilities of this new device and deepening understanding of key physics issues for the operation of ITER and the design of future fusion power plants. The impact of MHD

Externí odkaz: https://doaj.org/article/62bfb9a2df1a4c089aaf5aed50f1a433

New Natures : Joining Environmental History with Science and Technology Studies

Autor: Dolly Jørgensen, Finn Arne Jørgensen, Sara B. Pritchard

New Natures broadens the dialogue between the disciplines of science and technology studies (STS) and environmental history in hopes of deepening and even transforming understandings of human-nature interactions. The volume presents richly developed

A distal regulatory region of a class I human histone deacetylase

Autor: Nicolas D. Werbeck, Vaibhav Kumar Shukla, Micha B. A. Kunze, Havva Yalinca, Ruth B. Pritchard, Lucas Siemons, Somnath Mondal, Simon O. R. Greenwood, John Kirkpatrick, Charles M. Marson, D. Flemming Hansen

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)

Human Histone Deacetylases (HDACs) regulate gene expression and are important drug targets. Here, the authors combine NMR measurements, enzymatic assays and molecular dynamics simulations and show that HDAC8 samples a catalytically active and an inac

Externí odkaz: https://doaj.org/article/e6e3823b97f04066b0453b2d183e0a76

Characterising side chains in large proteins by protonless 13C-detected NMR spectroscopy

Autor: Ruth B. Pritchard, D. Flemming Hansen

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)

Analysis of side-chain motions by NMR has so far been restricted to small proteins and methyl-bearing side chains. Here, the authors present NMR methods based on 13C direct detection of highly deuterated protein samples that yield sharp and well-reso

Externí odkaz: https://doaj.org/article/0da10a54a94e459fb2afae5adb60909a

Periodontitis, Microbiomes and their Role in Alzheimer’s Disease

Autor: Anna B. Pritchard, StJohn Crean, Ingar Olsen, Sim K. Singhrao

Publikováno v: Frontiers in Aging Neuroscience, Vol 9 (2017)

As far back as the eighteenth and early nineteenth centuries, microbial infections were responsible for vast numbers of deaths. The trend reversed with the introduction of antibiotics coinciding with longer life. Increased life expectancy however, ac

Externí odkaz: https://doaj.org/article/35aafe385c744d2ab3115493510a64fc