Zobrazeno 1 - 10
of 151
pro vyhledávání: '"B. Plikaytis"'
Autor:
Subhadra Nandakumar, Sunil Kannanganat, Karen M Dobos, Megan Lucas, John S Spencer, Sunan Fang, Melissa A McDonald, Jan Pohl, Kristin Birkness, Venkateswarlu Chamcha, Melissa V Ramirez, Bonnie B Plikaytis, James E Posey, Rama Rao Amara, Suraj B Sable
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003705 (2013)
Glycosylation is the most abundant post-translational polypeptide chain modification in nature. Although carbohydrate modification of protein antigens from many microbial pathogens constitutes important components of B cell epitopes, the role in T ce
Externí odkaz:
https://doaj.org/article/fcf78577f37e4cc6977ecb1867a11d5d
Autor:
Brian Weiner, James Gomez, Thomas C Victor, Robert M Warren, Alexander Sloutsky, Bonnie B Plikaytis, James E Posey, Paul D van Helden, Nicolass C Gey van Pittius, Michael Koehrsen, Peter Sisk, Christian Stolte, Jared White, Sebastien Gagneux, Bruce Birren, Deborah Hung, Megan Murray, James Galagan
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e26038 (2012)
Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functi
Externí odkaz:
https://doaj.org/article/9d45c4662e0341f6ad7deca18843397f
Autor:
Suraj B Sable, Mani Cheruvu, Subhadra Nandakumar, Sunita Sharma, Kakali Bandyopadhyay, Kathryn L Kellar, James E Posey, Bonnie B Plikaytis, Rama Rao Amara, Thomas M Shinnick
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22718 (2011)
BACKGROUND: The identification of Mycobacterium tuberculosis vaccines that elicit a protective immune response in the lungs is important for the development of an effective vaccine against tuberculosis. METHODS AND PRINCIPAL FINDINGS: In this study,
Externí odkaz:
https://doaj.org/article/6e29d37e692a44a4b165617b0b79b2b9
Autor:
Sebastien Gagneux, Bruce W. Birren, Bhavana Muddukrishna, Robin M. Warren, Jennifer L. Gardy, B. Jesse Shapiro, Eric J. Rubin, Devinder Kaur, Midori Kato-Maeda, Megan Murray, Jamie E. Posey, Natalia Kurepina, Maha R. Farhat, Alistair Calver, Pardis C. Sabeti, Patrick Tang, Bonnie B. Plikaytis, Eric S. Lander, Alexander Sloutsky, Razvan Sultana, Mark L. Borowsky, Elizabeth M. Streicher, Thomas C. Victor, Karen R. Jacobson, Mabel Rodrigues, James C. Johnston, Karen J. Kieser, James E. Galagan, Barry N. Kreiswirth, Marco R. Oggioni
Publikováno v:
Nature genetics
PMC
PMC
M. tuberculosis is evolving antibiotic resistance, threatening attempts at tuberculosis epidemic control. Mechanisms of resistance, including genetic changes favored by selection in resistant isolates, are incompletely understood. Using 116 newly seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d5e35bf9f9ea754f834c6c4aef038f
http://europepmc.org/articles/PMC3887553
http://europepmc.org/articles/PMC3887553
Autor:
Megan Murray, Razvan Sultana, Analise Z. Reeves, Patricia J. Campbell, James E. Posey, Seidu Malik, Bonnie B. Plikaytis, Thomas M. Shinnick
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:1857-1865
Since the discovery of streptomycin's bactericidal activity against Mycobacterium tuberculosis , aminoglycosides have been utilized to treat tuberculosis (TB). Today, the aminoglycosides kanamycin and amikacin are used to treat multidrug-resistant (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6bc001cb1cb2cd3127fbe612a86f8b9
https://doi.org/10.1128/aac.02191-12
https://doi.org/10.1128/aac.02191-12
Autor:
Karen M. Dobos, Sunil Kannanganat, John S. Spencer, Bonnie B. Plikaytis, Megan Lucas, Subhadra Nandakumar, Rama Rao Amara, Suraj B. Sable, James E. Posey
Publikováno v:
Scientific Reports
Heterologous prime–boosting has emerged as a powerful vaccination approach against tuberculosis. However, optimal timing to boost BCG-immunity using subunit vaccines remains unclear in clinical trials. Here, we followed the adhesin Apa-specific T-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b91bbe530e00fa309511cc6bc38b4e
https://doi.org/10.1038/srep25837
https://doi.org/10.1038/srep25837
Autor:
Angela M. Starks, Beverly Metchock, R. David Sikes, Tracy Dalton, Delaina P. Hooks, Bonnie B. Plikaytis, Lauren S. Cowan, James E. Posey, Glenn P. Morlock, Patricia J. Campbell
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:2032-2041
The emergence of multi- and extensively drug-resistant tuberculosis is a significant impediment to the control of this disease because treatment becomes more complex and costly. Reliable and timely drug susceptibility testing is critical to ensure th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a75753b06c737ba8882b702f9deeb4c
https://doi.org/10.1128/aac.01550-10
https://doi.org/10.1128/aac.01550-10
Publikováno v:
Vaccine. 25:1553-1566
Tuberculosis caused by Mycobacterium tuberculosis continues to be one of the major public health problems in the world. The eventual control of this disease will require the development of a safe and effective vaccine. One of the approaches receiving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c55dcb5cddaa38ab436a519bf40800
https://doi.org/10.1016/j.vaccine.2006.11.014
https://doi.org/10.1016/j.vaccine.2006.11.014
Autor:
Laura Hickman, David Sikes, Angelina Mayorova, Thomas M. Shinnick, Bonnie B. Plikaytis, Janice Campos Caoili
Publikováno v:
Journal of Clinical Microbiology. 44:2378-2381
The TB-Biochip oligonucleotide microarray system is a rapid system to detect mutations associated with rifampin (RIF) resistance in mycobacteria. After optimizing the system with 29 laboratory-generated rifampin-resistant mutants of Mycobacterium tub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ff41daa50d3d7f688a031113081efb
https://doi.org/10.1128/jcm.00439-06
https://doi.org/10.1128/jcm.00439-06
Publikováno v:
Johansen, S K, Maus, C E, Plikaytis, B B & Douthwaite, S R 2006, ' Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2´-O-methylations in 16S and 23S rRNAs ', Molecular Cell, vol. 23, pp. 173-182 . https://doi.org/10.1016/j.molcel.2006.05.044, https://doi.org/10.1016/j.molcel.2006.05.044
The cyclic peptide antibiotics capreomycin and viomycin are generally effective against the bacterial pathogen Mycobacterium tuberculosis. However, recent virulent isolates have become resistant by inactivation of their tlyA gene. We show here that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2166d4e9af828f85c15cf42244b68e7b
https://doi.org/10.1016/j.molcel.2006.05.044
https://doi.org/10.1016/j.molcel.2006.05.044