Zobrazeno 1 - 10
of 15
pro vyhledávání: '"B. P. Watkins"'
Autor:
Sebastijan Hobor, Maise Al Bakir, Crispin T. Hiley, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. K. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Hilda van den Bos, Diana Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H. Rabinowitz, Laila Ait Hassou, Saskia Litière, D. Lucas Kerr, Lisa Tan, Gavin Kelly, David A. Moore, Matthew J. Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R. M. Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M. Blakely, Elza C. de Bruin, Floris Foijer, Karen H. Vousden, Trever G. Bivona, TRACERx consortium, Robert E. Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The phenomenon of mixed/heterogenous treatment responses to cancer therapies within an individual patient presents a challenging clinical scenario. Furthermore, the molecular basis of mixed intra-patient tumor responses remains unclear. Here
Externí odkaz:
https://doaj.org/article/a58c4b29e1d8491b8078212067633916
Autor:
Thomas B K Watkins, Emma C Colliver, Matthew R Huska, Tom L Kaufmann, Emilia L Lim, Cody B Duncan, Kerstin Haase, Peter Van Loo, Charles Swanton, Nicholas McGranahan, Roland F Schwarz
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 10, p e1011379 (2023)
Most computational methods that infer somatic copy number alterations (SCNAs) from bulk sequencing of DNA analyse tumour samples individually. However, the sequencing of multiple tumour samples from a patient's disease is an increasingly common pract
Externí odkaz:
https://doaj.org/article/813504d2d9cb4d0b820b2c0d5e22969e
Autor:
Tom L. Kaufmann, Marina Petkovic, Thomas B. K. Watkins, Emma C. Colliver, Sofya Laskina, Nisha Thapa, Darlan C. Minussi, Nicholas Navin, Charles Swanton, Peter Van Loo, Kerstin Haase, Maxime Tarabichi, Roland F. Schwarz
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-27 (2022)
Abstract Aneuploidy, chromosomal instability, somatic copy-number alterations, and whole-genome doubling (WGD) play key roles in cancer evolution and provide information for the complex task of phylogenetic inference. We present MEDICC2, a method for
Externí odkaz:
https://doaj.org/article/e4b330fa56874857bbfdc7ede9300d31
Autor:
Filipe Correia Martins, Dominique-Laurent Couturier, Ines de Santiago, Carolin Margarethe Sauer, Maria Vias, Mihaela Angelova, Deborah Sanders, Anna Piskorz, James Hall, Karen Hosking, Anumithra Amirthanayagam, Sabina Cosulich, Larissa Carnevalli, Barry Davies, Thomas B. K. Watkins, Ionut G. Funingana, Helen Bolton, Krishnayan Haldar, John Latimer, Peter Baldwin, Robin Crawford, Matthew Eldridge, Bristi Basu, Mercedes Jimenez-Linan, Andrew W. Mcpherson, Nicholas McGranahan, Kevin Litchfield, Sohrab P. Shah, Iain McNeish, Carlos Caldas, Gerard Evan, Charles Swanton, James D. Brenton
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Chromosomal instability is a major challenge to patient stratification and targeted drug development for high-grade serous ovarian carcinoma. Here we show that identification of clonal somatic copy number alterations in frequently amplified cancer ge
Externí odkaz:
https://doaj.org/article/63184752d1ca4e718d39186ab46bf815
Lower-thermospheric wind fluctuations measured with an FPI during pulsating aurora at Tromsø, Norway
Autor:
S. Oyama, K. Shiokawa, J. Kurihara, T. T. Tsuda, S. Nozawa, Y. Ogawa, Y. Otsuka, B. J. Watkins
Publikováno v:
Annales Geophysicae, Vol 28, Pp 1847-1857 (2010)
Simultaneous observations were conducted with a Fabry-Perot Interferometer (FPI) at a wavelength of 557.7 nm, an all-sky camera at a wavelength of 557.7 nm, and the European Incoherent Scatter (EISCAT) UHF radar during the Dynamics and Energetics
Externí odkaz:
https://doaj.org/article/9c629a0e9f224642ba4d3fc3148b956a
Publikováno v:
Annales Geophysicae, Vol 27, Pp 2699-2710 (2009)
Artificial E region field aligned plasma density irregularities (FAIs) were generated using HAARP in four different experimental modes and observed with a coherent scatter radar imager located 450 km to the southwest where it could detect field-al
Externí odkaz:
https://doaj.org/article/c98f937cac0549b0be996eb89437c1a8
Autor:
S. Oyama, B. J. Watkins, S. Maeda, H. Shinagawa, S. Nozawa, Y. Ogawa, A. Brekke, C. Lathuillere, W. Kofman
Publikováno v:
Annales Geophysicae, Vol 26, Pp 1491-1505 (2008)
Lower-thermospheric winds at high latitudes during moderately-disturbed geomagnetic conditions were studied using data obtained with the European Incoherent Scatter (EISCAT) Kiruna-Sodankylä-Tromsø (KST) ultrahigh frequency (UHF) radar system on
Externí odkaz:
https://doaj.org/article/219f92eee951469eb94c90645f553e4a
Autor:
H. Mori, M. Ishii, Y. Murayama, M. Kubota, K. Sakanoi, M.-Y. Yamamoto, Y. Monzen, D. Lummerzheim, B. J. Watkins
Publikováno v:
Annales Geophysicae, Vol 22, Pp 1613-1622 (2004)
This study is a statistical analysis on energy distribution of precipitating electrons, based on CNA (cosmic noise absorption) data obtained from the 256-element imaging riometer in Poker Flat, Alaska (65.11° N, 147.42° W), and optical data meas
Externí odkaz:
https://doaj.org/article/bb97f128fc48428f996d9972a66fda8c
Publikováno v:
Annales Geophysicae, Vol 20, Pp 679-690 (2002)
MF radar wind measurements in the mesosphere and lower thermosphere over Poker Flat, Alaska (65.1° N, 147.5° W) are used to study the features of mean winds and solar tides. Continuous observation with the newly installed radar is in progress
Externí odkaz:
https://doaj.org/article/cd374e5579934860a6b01c34c6fec68b
Publikováno v:
Animal Conservation. 11:247-254
Many seabirds are killed or injured by fishing gear, contributing to the high proportion of threatened seabirds. This study estimates the impact of the South African deep-water hake Merluccius spp. trawl fishery on seabirds. At least 30 birds were ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61a56af6d3ed9c03c30d591a6573ed7a
https://doi.org/10.1111/j.1469-1795.2008.00192.x
https://doi.org/10.1111/j.1469-1795.2008.00192.x