Výsledky vyhledávání - "B. O. L. Duke"

The co-administration of ivermectin and albendazole - safety, pharmacokinetics and efficacy againstOnchocerca volvulus

Autor: B. T. Quartey, Simon K. Attah, A. E. Ardrey, Kwablah Awadzi, E. T. Addy, B. O. L. Duke, Geoffrey Edwards, N. O. Opoku

Publikováno v: Annals of Tropical Medicine & Parasitology. 97:165-178

A randomized, double-blind, placebo-controlled trial was conducted, to determine whether the co-administration of ivermectin with albendazole is safe and more effective against Onchocerca volvulus than ivermectin alone, and whether a significant phar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb75d9bcc05a413854c7714b8bce384
https://doi.org/10.1179/000349803235001697

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Observations and reflections on the immature stages ofOnchocerca volvulusin the human host

Autor: B. O. L. Duke

Publikováno v: Annals of Tropical Medicine & Parasitology. 85:103-110

Knowledge of the morphology, migrations and development rates of the L3, L4 and prepubertal L5 stages of Onchocerca volvulus in the vertebrate host is an essential prerequisite to work vaccine development of chemoprophylaxis. After a brief review of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b322016588cf07568b6337254042d62d
https://doi.org/10.1080/00034983.1991.11812536

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Evidence for macrofilaricidal activity of ivermectin against female Onchocerca volvulus: further analysis of a clinical trial in the Republic of Cameroon indicating two distinct killing mechanisms

Autor: B. O. L. Duke

Publikováno v: Parasitology. 130(Pt 4)

During a 3-year trial of the effects of ivermectin (MectizanR) on adult worms and microfilariae of Onchocerca volvulus in the Republic of Cameroon, comparison was made between the percentages of calcified and uncalcified moribund (M) and dead (D) adu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975a549f6e471a0b98b681ac8ce1ac8d
https://pubmed.ncbi.nlm.nih.gov/15830819

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Neoplastic change in Onchocerca volvulus and its relation to ivermectin treatment

Autor: A.M. Marty, B. O. L. Duke, Joseph Kamgno, S. D. S. Pion, Jacques Gardon, Michel Boussinesq, D.L. Peet

Publikováno v: Parasitology. 125(Pt 5)

A pleomorphic neoplasm (PN) is described from sections of Onchocerca volvulus worms in nodules excised from Cameroonian patients. PN is confined to older, non-fecund, female worms, and those classed as moribund/dead. It is mainly composed of small, r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcb751c5de55d031df1a44fa0457184
https://pubmed.ncbi.nlm.nih.gov/12458827

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Onchocerciasis control in Uganda: how can self-sustaining, community-based treatment with ivermectin be achieved?

Autor: B. O. L. Duke, D. Mutabazi

Publikováno v: Annals of tropical medicine and parasitology. 92(2)

In Uganda, the control of onchocerciasis by mass treatment with ivermectin (Mectizan) began in 1990 and has expanded greatly since 1992. The parties involved in the programme are the Uganda Ministry of Health and its National Onchocerciasis Task Forc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19d5d5516e3b3a64dc55b6b985cb809
https://pubmed.ncbi.nlm.nih.gov/9625916

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The safety and efficacy of amocarzine in African onchocerciasis and the influence of ivermectin on the clinical and parasitological response to treatment

Autor: P. K. Nyame, Simon K. Attah, E. T. Addy, N. A. Kshirsagar, N. O. Opoku, Kwablah Awadzi, B. O. L. Duke

Publikováno v: Annals of tropical medicine and parasitology. 91(3)

The hundred men from a forest area of Ghana, without vector control or ivermectin distribution, were randomized to receive a single dose of ivermectin (150 micrograms/kg body weight) on day 1 followed by amocarzine (3 mg/kg twice daily after meals) o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e704ab0b17c8be64e39e1bf0b8c238
https://pubmed.ncbi.nlm.nih.gov/9229021

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Effect of diethylcarbamazine on adult Loa in monkeys

Autor: B. O. L. Duke

Publikováno v: Annals of tropical medicine and parasitology. 84(4)

The effect of diethylcarbamazine citrate (DEC) treatment (43-150 mg kg-1 daily for 12-21 days) on adult Loa worms in five drills (Mandrillus leucophaeus) is described. In individual monkeys, between one-third and all of the adult worms survived the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41ec118f7049139305608beed5871f4
https://pubmed.ncbi.nlm.nih.gov/2260903

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