Zobrazeno 1 - 10
of 265
pro vyhledávání: '"B. Nicol"'
Autor:
Phillip B. Nicol, Danielle Paulson, Gege Qian, X. Shirley Liu, Rafael Irizarry, Avinash D. Sahu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Single-cell transcriptomics has emerged as a powerful tool for understanding how different cells contribute to disease progression by identifying cell types that change across diseases or conditions. However, detecting changing cell types is
Externí odkaz:
https://doaj.org/article/4f488a03a7a34c2f888328d58652862e
Autor:
Martin Kaufmann, Natasha Iaboni, Amoon Jamzad, David Hurlbut, Kevin Yi Mi Ren, John F. Rudan, Parvin Mousavi, Gabor Fichtinger, Sonal Varma, Antonio Caycedo-Marulanda, Christopher J. B. Nicol
Publikováno v:
Metabolites, Vol 13, Iss 4, p 508 (2023)
Colorectal cancer (CRC) is the second leading cause of cancer deaths. Despite recent advances, five-year survival rates remain largely unchanged. Desorption electrospray ionization mass spectrometry imaging (DESI) is an emerging nondestructive metabo
Externí odkaz:
https://doaj.org/article/4282cf5ad5d44339910afe1cc2170a76
Autor:
Phillip B. Nicol, Danielle Paulson, Gege Qian, X. Shirley Liu, Rafael Irizarry, Avinash D. Sahu
Single-cell transcriptomics has emerged as a powerful tool for understanding how different cells contribute to disease progression by identifying cell types that change across diseases or conditions. However, detecting changing cell types is challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9c07a3c2fecf92e30896c607e8fa796
https://doi.org/10.1101/2023.05.06.539326
https://doi.org/10.1101/2023.05.06.539326
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Comput Syst Oncol
MotivationCancer progression, including the development of intratumor heterogeneity, is inherently a spatial process. Mathematical models of tumor evolution can provide insights into patterns of heterogeneity that can emerge in the presence of spatia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fddfa033035050a0ec32e4fe8f8b41
https://doi.org/10.1002/cso2.1033
https://doi.org/10.1002/cso2.1033
Autor:
Danai G. Topouza, Jihoon Choi, Sean Nesdoly, Anastasiya Tarnouskaya, Christopher J. B. Nicol, Qing Ling Duan
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4875
High-grade serous ovarian cancer (HGSOC) is a highly lethal gynecologic cancer, in part due to resistance to platinum-based chemotherapy reported among 20% of patients. This study aims to generate novel hypotheses of the biological mechanisms underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ac127ed0e3ad12b78e08de1a78408b
Autor:
Laura van Zelst, Sanne van Zanten, Shengqing Gu, Joost Rens, Phillip B. Nicol, Nishanth Ulhas Nair, Collin Tokheim, Chenfei Wang, Avinash Das Sahu, Xiaoqing Wang, Xiaoman Wang, Dejan Juric, Mark Musters, Wubing Zhang, Myles Brown, Keith T. Flaherty, Gege Qian, Cliff Meyer, David E. Fisher, Zexian Zeng, Jenny Worthington, Inge Leenders, Jan Klomp, Arthur Oubrie, Bas Jansen, Jin Wang, Phillip Munson, Jun Liu, Jaap Lemmers, Meriem Bourajjaj, Jingxin Fu, X. Shirley Liu
Drugs that kill tumors through multiple mechanisms have potential for broad clinical benefits, with a reduced propensity to resistance. We developed BipotentR, a computational approach to find cancer-cell-specific regulators that simultaneously modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6343ed7cd5856d6a9df6a2a16296e1ef
https://doi.org/10.1101/2021.10.25.465724
https://doi.org/10.1101/2021.10.25.465724
Autor:
R.P. Sharma, L. Wolters, B.T. Braak, M. Niemeijer, C. Sparham, B. Nicol, A. White, B. van de Water, A.M. Middleton, J.B. Beltman
Publikováno v:
Toxicology Letters. 368:S288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69b9f001cd6d21a8085da58b617eda3b
https://doi.org/10.1016/j.toxlet.2022.07.756
https://doi.org/10.1016/j.toxlet.2022.07.756