Zobrazeno 1 - 10
of 846
pro vyhledávání: '"B. McNamara"'
Autor:
Georgina A. Craig, Lucy Ryan, Jessica Thapar, Niamh B. McNamara, Alana Hoffmann, Danielle Page, Jamie Rose, Simon R. Cox, Veronique E. Miron
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The structural integrity of myelin sheaths in the central nervous system (CNS) is crucial for the maintenance of its function. Electron microscopy (EM) is the gold standard for visualizing individual myelin sheaths. However, the tissue processing inv
Externí odkaz:
https://doaj.org/article/5604a8ff881640db8ef279fd21e834c1
Autor:
Costanza Lo Cascio, Tigran Margaryan, Ernesto Luna-Melendez, James B. McNamara, Connor I. White, William Knight, Saisrinidhi Ganta, Zorana Opachich, Claudia Cantoni, Wonsuk Yoo, Nader Sanai, Artak Tovmasyan, Shwetal Mehta
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
Histone deacetylase (HDAC) inhibitors have garnered considerable interest for the treatment of adult and pediatric malignant brain tumors. However, owing to their broad-spectrum nature and inability to effectively penetrate the blood-brain barrier, H
Externí odkaz:
https://doaj.org/article/fde3c2b5ee5b4f4fac16366a31d2b804
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Sexual signalling is a key feature of reproductive investment, yet the effects of immune system activation on investment into chemical signalling, and especially signal receiver traits such as antennae, are poorly understood. We explore how
Externí odkaz:
https://doaj.org/article/bcf0598e527b4596904f2569f216c6ad
Autor:
Costanza Lo Cascio, James B. McNamara, Ernesto L. Melendez, Erika M. Lewis, Matthew E. Dufault, Nader Sanai, Christopher L. Plaisier, Shwetal Mehta
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Glioblastoma (GBM) is characterized by an aberrant yet druggable epigenetic landscape. One major family of epigenetic regulators, the histone deacetylases (HDACs), are considered promising therapeutic targets for GBM due to their repressive influence
Externí odkaz:
https://doaj.org/article/0c28bf317c584da09eb9a6ee5bd8d523
Publikováno v:
Behavioral Ecology. 34:468-479
The terminal investment hypothesis proposes that, when individuals are faced with a threat to survival, they will increase investment in current reproduction. The level of the threat necessary to elicit terminal investment (the dynamic terminal inves
Publikováno v:
Biological Reviews.
Autor:
Nikolas J. Willmott, Bob B. M. Wong, Elizabeth C. Lowe, Kathryn B. McNamara, Therésa M. Jones
Publikováno v:
The Quarterly Review of Biology. 97:15-35
Autor:
Niamh B. McNamara, David A. D. Munro, Nadine Bestard-Cuche, Akiko Uyeda, Jeroen F. J. Bogie, Alana Hoffmann, Rebecca K. Holloway, Irene Molina-Gonzalez, Katharine E. Askew, Stephen Mitchell, William Mungall, Michael Dodds, Carsten Dittmayer, Jonathan Moss, Jamie Rose, Stefan Szymkowiak, Lukas Amann, Barry W. McColl, Marco Prinz, Tara L. Spires-Jones, Werner Stenzel, Karen Horsburgh, Jerome J. A. Hendriks, Clare Pridans, Rieko Muramatsu, Anna Williams, Josef Priller, Veronique E. Miron
Publikováno v:
Nature 613(7942), 120-129 (2023). doi:10.1038/s41586-022-05534-y
Myelin is required for the function of neuronal axons in the central nervous system, but the mechanisms that support myelin health are unclear. Although macrophages in the central nervous system have been implicated in myelin health1, it is unknown w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228d404a8611c8450df3d12b1580b5c6
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