Zobrazeno 1 - 10
of 176
pro vyhledávání: '"B. Masereel"'
Autor:
P.H. Ciza, P.-Y. Sacre, C. Waffo, T.M. Kimbeni, B. Masereel, Ph Hubert, E. Ziemons, R.D. Marini
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 215
Chemometrics applied to spectroscopic measurements such as near-infrared are gaining more and more importance for quality control of pharmaceutical products. Handheld near-infrared devices show great promise as a medicines quality screening technique
Autor:
Philippe Morimont, B. Masereel, Philippe Kolh, P. Benoit, Vincenzo D'Orio, Paul Gérard, Vincent Tchana-Sato, Jean-Michel Dogné, Alexandre Ghuysen, Bernard Lambermont, Raymond Limet
Publikováno v:
Archives of Physiology and Biochemistry. 111:217-223
We studied the effects on pulmonary hemodynamics of U-46619, a thromboxane A2 (TXA2) agonist, before and after administration of a novel TXA2 receptor antagonist and synthase inhibitor (BM-573). Six anesthetized pigs (Ago group) received 6 consecutiv
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 65:67-72
The pharmacomodulation of sulfonylureas structurally related to torasemide and characterized by a TXA(2)antagonism led to the synthesis of BM-573. This original molecule showed a high affinity (IC(50)1.3 nM) for the TXA(2)receptor of human platelets
Autor:
Stéphanie Rolin, Johan Wouters, B. Masereel, Jacques Delarge, Jean-Michel Dogné, P. Neven, X. De Leval
Publikováno v:
Pharmacy and Pharmacology Communications. 6:77-82
Because torasemide, a loop diuretic, dose-dependently relaxes canine coronary artery precontracted with thromboxane A2 (TxA2), a series of pyridine derivatives have been investigated with the aim of developing original TxA2 receptor antagonists. A bi
Publikováno v:
Epilepsia. 38:334-337
The N-[(4-cycloheptylaminopyrid-3-yl)sulfonyl]-N'-cycloheptyl urea, a neuroprotective agent, and 10 chemically related sulfonyl(thio)ureas were evaluated in the maximal electroshock seizure test in mice. This sulfonylurea, BM 27, and two stucturally
Publikováno v:
Acta chirurgica Belgica. 113(4)
Gastrointestinal tract duplications are uncommon congenital abnormalities, that may occur anywhere along the alimentary tract. Most frequently they occur at the level of the small bowel tract and are symptomatic before the age of two.In our case we r
Autor:
Jean-François Liégeois, B Masereel, P. de Tullio, Léon Dupont, Jacques Delarge, Didier Laeckmann, Bernard Pirotte
Publikováno v:
European Journal of Medicinal Chemistry. 30:343-351
Publikováno v:
European Journal of Medicinal Chemistry. 29:527-535
The pharmacology of lipophilic 4-arylamino- and 4-cycloalkylaminopyrid-3-ylsulfonyl(thio)ureas and their synthesis designed from torasemide are described. These compounds could lead to a method of inhibiting the astrocytic Na+ 2C1− K+ cotransporter
Publikováno v:
ChemInform. 25
Autor:
Jeanine Fontaine, J. Delarge, O. Diouf, Ph. Lebrun, B. Masereel, L. Dupont, P. de Tullio, M. H. Antoine, S. Khelili, R. Ouedraogo, Tchao Podona, B. Pirotte, Carine Maggetto
Publikováno v:
ChemInform. 27