Zobrazeno 1 - 10
of 52
pro vyhledávání: '"B. Martin Hallberg"'
Autor:
Marco Mandolesi, Hrishikesh Das, Liset de Vries, Yiqiu Yang, Changil Kim, Manojj Dhinakaran, Xaquin Castro Dopico, Julian Fischbach, Sungyong Kim, Mariia V. Guryleva, Monika Àdori, Mark Chernyshev, Aron Stålmarck, Leo Hanke, Gerald M. McInerney, Daniel J. Sheward, Martin Corcoran, B. Martin Hällberg, Ben Murrell, Gunilla B. Karlsson Hedestam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The continued evolution of SARS-CoV-2 underscores the need to understand qualitative aspects of the humoral immune response elicited by spike immunization. Here, we combine monoclonal antibody (mAb) isolation with deep B cell receptor (BCR)
Externí odkaz:
https://doaj.org/article/dd5bb1c8958649a5ad5a309a8a4fa7ee
Autor:
Miriam Cipullo, Genís Valentín Gesé, Shreekara Gopalakrishna, Annika Krueger, Vivian Lobo, Maria A. Pirozhkova, James Marks, Petra Páleníková, Dmitrii Shiriaev, Yong Liu, Jelena Misic, Yu Cai, Minh Duc Nguyen, Abubakar Abdelbagi, Xinping Li, Michal Minczuk, Markus Hafner, Daniel Benhalevy, Aishe A. Sarshad, Ilian Atanassov, B. Martin Hällberg, Joanna Rorbach
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Mitochondrial gene expression relies on mitoribosomes to translate mitochondrial mRNAs. The biogenesis of mitoribosomes is an intricate process involving multiple assembly factors. Among these factors, GTP-binding proteins (GTPBPs) play impo
Externí odkaz:
https://doaj.org/article/7e993f34f7d84d7d9dd49ff3b7ab5aba
Autor:
Pei-Shang Wu, B. Martin Hallberg, Elin Enervald, Angelica Joelsson, Dorothea Rutishauser, Carina Palmberg, Lena Ström
Publikováno v:
Genetics. 216:1009-1022
Double-strand breaks that are induced postreplication trigger establishment of damage-induced cohesion in Saccharomyces cerevisiae, locally at the break site and genome-wide on undamaged chromosomes. The translesion synthesis polymerase, polymerase
Publikováno v:
Nat Commun
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Mitochondrial ribosomes (mitoribosomes) synthesize a critical set of proteins essential for oxidative phosphorylation. Therefore, mitoribosomal function is vital to the cellular energy supply. Mitoribosome biogenesis follows distinct molecular pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe32cc44c2b305ae1b7795c83a72cdab
https://doi.org/10.21203/rs.3.rs-253032/v1
https://doi.org/10.21203/rs.3.rs-253032/v1
Autor:
Natalia Ruetalo, Hejun Liu, Leo Hanke, Jonathan L. Schmid-Burgk, Jan M. P. Tödtmann, Yonas M. Tesfamariam, Hrishikesh Das, Florian I. Schmidt, Caroline I. Fandrey, Sabine Normann, Paul-Albert Koenig, Kerstin U. Ludwig, Matthias Geyer, Michael Schindler, Xueyong Zhu, Beate M. Kümmerer, Lea-Marie Jenster, Nicholas C. Wu, Miki Uchima, Karl Gatterdam, Ian A. Wilson, Meng Yuan, Lisa D. J. Schiffelers, Florian N. Gohr, Hiroki Kato, Jannik Boos, B. Martin Hallberg, Steffen Pritzl, Jennifer Deborah Wuerth, Maria H Christensen
Publikováno v:
Science
Signal Transduction and Targeted Therapy
Science (New York, N.y.)
Signal Transduction and Targeted Therapy
Science (New York, N.y.)
A double punch against SARS-CoV-2 Monoclonal antibodies are an important weapon in the battle against COVID-19. However, these large proteins are difficult to produce in the needed quantities and at low cost. Attention has turned to nanobodies, which
Autor:
B. Martin Hallberg, Hrishikesh Das, Gerald M. McInerney, Ainhoa Moliner Morro, Martin Corcoran, Adnane Achour, Ben Murrell, Tim Schulte, Daniel J. Sheward, Gunilla B. Karlsson Hedestam, Laura Vidakovics Perez, Leo Hanke
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
SARS-CoV-2 enters host cells through an interaction between the spike glycoprotein and the angiotensin converting enzyme 2 (ACE2) receptor. Directly preventing this interaction presents an attractive possibility for suppressing SARS-CoV-2 replication
Publikováno v:
Nucleic Acids Research
Mitochondrial polycistronic transcripts are extensively processed to give rise to functional mRNAs, rRNAs and tRNAs; starting with the release of tRNA elements through 5′-processing by RNase P (MRPP1/2/3-complex) and 3′-processing by RNase Z (ELA
Publikováno v:
'Nucleic Acids Research ', vol: 43, pages: 5664-5672 (2015)
Nucleic Acids Research
Nucleic Acids Research
Mitochondrial RNA polymerase produces long polycistronic precursors that contain the mRNAs, rRNAs and tRNAs needed for mitochondrial translation. Mitochondrial RNase P (mt-RNase P) initiates the maturation of the precursors by cleaving at the 5′ en
Publikováno v:
Nucleic Acids Research
A single-subunit RNA polymerase, POLRMT, transcribes the mitochondrial genome in human cells. Recently, a factor termed as the mitochondrial transcription elongation factor, TEFM, was shown to stimulate transcription elongation in vivo, but its effec
Autor:
Mikalai Lapkouski, B. Martin Hallberg
Publikováno v:
'Nucleic Acids Research ', vol: 43, pages: 9065-9075 (2015)
Nucleic Acids Research
Nucleic acids symposium series 43(18), 9065-9075 (2015). doi:10.1093/nar/gkv861
Nucleic Acids Research
Nucleic acids symposium series 43(18), 9065-9075 (2015). doi:10.1093/nar/gkv861
Polyadenylation, performed by poly(A) polymerases (PAPs), is a ubiquitous post-transcriptional modification that plays key roles in multiple aspects of RNA metabolism. Although cytoplasmic and nuclear PAPs have been studied extensively, the mechanism