Zobrazeno 1 - 10
of 216
pro vyhledávání: '"B. Mackness"'
Autor:
B. Mackness, A. E. Smith, M. I. Mackness, M. Dippnall, Nicola Cherry, Andrew C. Povey, P.N. Durrington
Publikováno v:
Occupational Medicine. 55:282-286
Serum paraoxonase (PON1) provides protection against organophosphate induced toxicity. Recently we reported that the frequency of paraoxonase polymorphisms in sheep dippers with self-reported chronic ill-health differed from that in dippers with a si
Autor:
B, Mackness, M, Mackness
Publikováno v:
Panminerva medica. 54(2)
High-density lipoprotein (HDL) is protective against atherosclerosis development. Other than its central role in reverse cholesterol transport, HDL exhibits several other mechanisms by which it is protective. These include antioxidative, anti-inflamm
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 52(5)
Homocysteine (Hcy)-thiolactonase (HTase) activity of the paraoxonase-1 (PON1) protein detoxifies Hcythiolactone in human blood and could thus delay the development of atherosclerosis. We investigated a hypothesis that HTase activity is associated wit
Publikováno v:
European journal of clinical investigation. 32(4)
The oxidation of low-density lipoprotein (LDL) is central to current theories on the initiation and progression of atherosclerosis. Type 1 diabetes is associated with an increase in oxidative stress, which may be responsible for the increased suscept
Publikováno v:
The Biochemical journal. 354(Pt 1)
Human serum paraoxonase (human PON1) has been shown to be important in the metabolism of phospholipid and cholesteryl ester hydroperoxides, thereby preventing the oxidation of low-density lipoprotein (LDL) and retarding atherogenesis. However, the ex
Autor:
M, Mackness, A, Boullier, N, Hennuyer, B, Mackness, M, Hall, A, Tailleux, P, Duriez, B, Delfly, P, Durrington, J C, Fruchart, N, Duverger, J M, Caillaud, G, Castro, A, Bouiller
Publikováno v:
Biochemical and biophysical research communications. 269(1)
Serum paraoxonase (PON1) is believed to protect against the development of atherosclerosis because of its ability to retard the oxidation of low-density lipoprotein (LDL) by hydrolysing LDL-associated phospholipid and cholesteryl-ester hydroperoxides
Autor:
B, MacKness, M I, Mackness, P N, Durrington, S, Arrol, A E, Evans, D, McMaster, J, Ferrières, J B, Ruidavets, N R, Williams, A N, Howard
Publikováno v:
European journal of clinical investigation. 30(1)
The rate of coronary heart disease is over three-fold greater in Belfast than in Toulouse and the excess risk cannot be totally explained by 'classical' risk factors such as total cholesterol, LDL-cholesterol, smoking, etc.The effect of the human ser
Akademický článek
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Akademický článek
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Publikováno v:
Atherosclerosis. 151:57