Výsledky vyhledávání - "B. M. Peterlin"

HIV-1 Nef and CycK:CDK13 antagonize SERINC5 for optimal viral infectivity

Autor: Rongrong Li, Liangliang Sun, Iqbal Ahmad, X. Shen, S. F. Johnson, M. K. Collins, Jianjun Hu, Dylan A. Frabutt, Zhichang Yang, Qingqing Chai, Yong Hui Zheng, B. M. Peterlin, Sunan Li, Judd F. Hultquist

SummaryHIV-1 Nef antagonizes SERINC5 by redirecting this potent restriction factor to the endosomes and lysosomes for degradation. However, the precise mechanism remains unclear. Using affinity purification/mass spectrometry, we identified cyclin K a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df2ff9886874a3ea65cac5df004b79dd
https://doi.org/10.1101/2021.05.24.445478

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Nef from Human Immunodeficiency Virus Type 1 F12 Inhibits Viral Production and Infectivity

Autor: B M Peterlin, A S Baur, Maurizio Federico, Paola D'Aloja, Oliver T. Fackler

Publikováno v: Journal of Virology. 75:6601-6608

Human immunodeficiency virus type 1 F12 (HIV-1 F12 ) interferes with the replication of other strains of HIV. Its accessory protein, Nef, is sufficient for this phenotype, where the production and infectivity of HIV are impaired significantly. The an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8d9068949895feaaa36a83c9a269f1
https://doi.org/10.1128/jvi.75.14.6601-6608.2001

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HIV-1 Replication Is Inhibited by a Pseudo-substrate Peptide That Blocks Tat Transactivation

Autor: Takashi Okamoto, B M Peterlin, Hiroshi Okamoto, Thomas P. Cujec

Publikováno v: Virology. 270:337-344

The activation of the HIV-1 long terminal repeat (LTR) by the viral transcriptional transactivator Tat is an essential step in the viral replication cycle. To increase the processivity of RNA polymerase II, Tat interacts with the positive transcripti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33dc8367ec25fd49005216180fb7187
https://doi.org/10.1006/viro.2000.0311

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Complex Architecture of Major Histocompatibility Complex Class II Promoters: Reiterated Motifs and Conserved Protein-Protein Interactions

Autor: Nabila Jabrane-Ferrat, Jeremy M. Boss, B M Peterlin, Joseph D. Fontes

Publikováno v: Scopus-Elsevier

The S box (also known as at the H, W, or Z box) is the 5'-most element of the conserved upstream sequences in promoters of major histocompatibility complex class II genes. It is important for their B-cell-specific and interferon gamma-inducible expre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae971f448cf52eeb11393eaa09f17ddc
https://doi.org/10.1128/mcb.16.9.4683

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Ets-1 Activates the DRA Promoter in B Cells

Autor: B M Peterlin, Nabila Jabrane-Ferrat

Publikováno v: Scopus-Elsevier

The X box in promoters of class II major histocompatibility complex genes plays a crucial role in the B-cell-specific and gamma interferon-inducible expression of these genes. The sequence TTCC is located in the pyrimidine tract which extends 5' to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd3eaf835834dee6921ad7c12f078d4
https://doi.org/10.1128/mcb.14.11.7314-7321.1994

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CONTROL OF RNA INITIATION AND ELONGATION AT THE HIV-1 PROMOTER

Autor: B M Peterlin, Katherine A. Jones

Publikováno v: Annual Review of Biochemistry. 63:717-743

THE HIV-l PROMOTER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718 Distal Enhancer Sequences . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 718 T Cell Activation Signals and NF-KlJ .. .. . .. .......

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76125ad0703cecd4b5a7d3018d8baf8
https://doi.org/10.1146/annurev.bi.63.070194.003441

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Effects of CD45 on NF-kappa B. Implications for replication of HIV-1

Autor: A Baur, S Garber, B M Peterlin

Publikováno v: The Journal of Immunology. 152:976-983

Increased levels of replication of the HIV type 1 are observed after the activation of infected T cells through the TCR. However, anti-CD45 antibodies inhibit these effects in cells from infected individuals. In this study, we examined interrelations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::466dd940292292f53aceb59738c05f9d
https://doi.org/10.4049/jimmunol.152.3.976

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The major histocompatibility complex class II promoter-binding protein RFX (NF-X) is a methylated DNA-binding protein

Autor: Xian-Yang Zhang, Sanja Samac, B M Peterlin, Melanie Ehrlich, Nabila Jabrane-Ferrat, Clement Asiedu

Publikováno v: Scopus-Elsevier

A mammalian protein called RFX or NF-X binds to the X box (or X1 box) in the promoters of a number of major histocompatibility (MHC) class II genes. In this study, RFX was shown to have the same DNA-binding specificity as methylated DNA-binding prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d85c7473c46b4013fbaa4d653c36e48
https://doi.org/10.1128/mcb.13.11.6810

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Functional analysis of interactions between Tat and the trans-activation response element of human immunodeficiency virus type 1 in cells

Autor: Tristram G. Parslow, S. J. Madore, B M Peterlin, Ying Luo, Bryan R. Cullen

Publikováno v: Journal of Virology. 67:5617-5622

Transcriptional trans-activation of the human immunodeficiency virus type 1 long terminal repeat requires that the virally encoded Tat effector interacts with its target trans-activation response element (TAR) RNA stem-loop. Although the arginine-ric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e6585318bfde742d7a084c3ed12326
https://doi.org/10.1128/jvi.67.9.5617-5622.1993

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