Výsledky vyhledávání - "B. M. Blumberg"

Macrophage tropism determinants of human immunodeficiency virus type 1 in vivo

Autor: B. M. Blumberg, Beatrice H. Hahn, George M. Shaw, Richard W. Price, Leon G. Epstein, David B. Trowbridge, Peter Westervelt, Lee Ratner, Y. Li

Publikováno v: Journal of Virology. 66:2577-2582

Strains of human immunodeficiency virus type 1 differ in their abilities to infect and replicate in primary human macrophages. Chimeric clones were constructed from a provirus unable to infect macrophages (NLHX) and envelope sequences (V3 loop) of vi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ed78da771e125d51411398ffc8c453
https://doi.org/10.1128/jvi.66.4.2577-2582.1992

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Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis

Autor: S, Krajewski, H J, James, J, Ross, B M, Blumberg, L G, Epstein, H E, Gendelman, S, Gummuluru, S, Dewhurst, L R, Sharer, J C, Reed, H A, Gelbard

Publikováno v: Neuropathology and applied neurobiology. 23(3)

We have previously demonstrated the presence of DNA fragmentation in neurons, macrophages and microglia consistent with apoptosis, but not in reactive astrocytes in brain tissue from paediatric patients with HIV-1 encephalitis (HIVE). To further unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::501f9ea3547a6c5c1e3519b915846182
https://pubmed.ncbi.nlm.nih.gov/9223134

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In situ amplification and detection of HIV-1 DNA in fixed pediatric AIDS brain tissue

Autor: L R, Sharer, Y, Saito, A, Da Cunha, P C, Ung, H A, Gelbard, L G, Epstein, B M, Blumberg

Publikováno v: Human pathology. 27(6)

To examine whether latent infection by HIV-1 occurs in the central nervous system, we optimized a procedure for amplification and detection of HIV-1 DNA in situ, in formalin-fixed brain tissue from a child with severe HIV-1-associated progressive enc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::689fe55406e2de048ce5e278e5f24f0e
https://pubmed.ncbi.nlm.nih.gov/8666375

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Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy

Autor: H A, Gelbard, H J, James, L R, Sharer, S W, Perry, Y, Saito, A M, Kazee, B M, Blumberg, L G, Epstein

Publikováno v: Neuropathology and applied neurobiology. 21(3)

The pathogenesis of human immunodeficiency virus type 1 (HIV-1) associated dementia in adults involves neuronal loss from discrete areas of the neocortex and subcortical regions, but the mechanism for neuronal death is poorly understood. Gene-directe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a2a9191400315fad80feb8ccd3c10eb
https://pubmed.ncbi.nlm.nih.gov/7477729

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Interaction of HIV-1 and human salivary mucins

Autor: E J, Bergey, M I, Cho, B M, Blumberg, M L, Hammarskjöld, D, Rekosh, L G, Epstein, M J, Levine

Publikováno v: Journal of acquired immune deficiency syndromes. 7(10)

Previous studies have suggested that salivary secretions may act as inhibitors of HIV-1 replication in vitro. This inhibitory activity was determined to be associated mainly with secretions obtained from the human submandibular-sublingual glands, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1cc1b7da0690237d01b5492d5dd62f93
https://pubmed.ncbi.nlm.nih.gov/8083829

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Overexpression of nef as a marker for restricted HIV‐1 infection of astrocytes in postmortem pediatric central nervous tissues

Autor: T. A. Cvetkovich, J. Michaels, B. M. Blumberg, Leon G. Epstein, Y. Saito, M. Mintz, K. Golding, Leroy R. Sharer, M. Louder

Publikováno v: Neurology. 44:474-474

In previous studies, using polymerase chain reaction amplification of HIV-1 genes directly from pathologic tissues of children who died with AIDS encephalopathy, we showed that the reading frame of the HIV-1 regulatory nef gene is open, suggesting th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14fbf943c2ac9203cf2d4734cb8ff02
https://doi.org/10.1212/wnl.44.3_part_1.474

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Intracellular vesicular stomatitis virus leader RNAs are found in nucleocapsid structures

Autor: B M Blumberg, D Kolakofsky

Publikováno v: Journal of Virology. 40:568-576

Previous studies demonstrated that cytoplasmic extracts of cells infected with vesicular stomatitis virus contain plus-strand leader RNAs which sediment at 18S on sucrose gradients as a complex with viral N protein. The work presented in this paper d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eab0c89a60f509e416091031dd76751
https://doi.org/10.1128/jvi.40.2.568-576.1981

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Kinetic evidence for the obligatory formation of a 30S initiation complex in polyphenylalanine synthesis initiated with N-acetylphenylalanyl-5RNA

Autor: B M, Blumberg, T, Nakamoto, I S, Goldberg

Publikováno v: Biochemistry. 14(13)

The problem of whether the initiation of bacterial protein synthesis involves the obligatory formation of a 30S initiation complex intermediate was examined in a model system with N-acetylphenylalanyl-tRNA as initiator 5RNA nad poly(uridylic acid) as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a4937d40a5d4de1c4ab92c3568fff91
https://pubmed.ncbi.nlm.nih.gov/1096935

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