Zobrazeno 1 - 10
of 66
pro vyhledávání: '"B. Lozanoska-Ochser"'
Autor:
V. Marrocco, P. Fiore, A. Benedetti, S. Pisu, E. Rizzuto, A. Musarò, L. Madaro, B. Lozanoska-Ochser, M. Bouché
Publikováno v:
EBioMedicine, Vol 16, Iss C, Pp 150-161 (2017)
Inflammation plays a considerable role in the progression of Duchenne Muscular Dystrophy (DMD), a severe muscle disease caused by a mutation in the dystrophin gene. We previously showed that genetic ablation of Protein Kinase C θ (PKCθ) in mdx, the
Externí odkaz:
https://doaj.org/article/d23751d40f3f41b0b91b7547c501b493
Akademický článek
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Autor:
Mark Peakman, B. Lozanoska-Ochser
Publikováno v:
Clinical and Experimental Immunology. 157:119-127
SummaryAn important prerequisite for development of insulitis and β-cell destruction in type 1 diabetes is successful transmigration of autoreactive T cells across the islet endothelium. Previous work suggests that antigen presentation to T cells by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1144f5bba14513292465c11adc96d560
https://doi.org/10.1111/j.1365-2249.2009.03940.x
https://doi.org/10.1111/j.1365-2249.2009.03940.x
Autor:
Richard Ellis, Jennifer M. Tremble, Jennifer S. Allen, Ania Skowera, R. David G. Leslie, Mark Peakman, Chloe L. Rackham, Timothy Tree, Colin M. Dayan, B. Lozanoska-Ochser, Karl Pang
Publikováno v:
Diabetes
OBJECTIVE—Immune-mediated destruction of β-cells resulting in type 1 diabetes involves activation of proinflammatory, islet autoreactive T-cells, a process under the control of dendritic cells of the innate immune system. We tested the hypothesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049a2bf2873ab2b3c39fa2d3713285c5
https://doi.org/10.2337/db08-0964
https://doi.org/10.2337/db08-0964
Publikováno v:
The Journal of Immunology. 181:6109-6116
Pancreatic islet endothelial cells (ECs) form the barrier across which autoreactive T cells transmigrate during the development of islet inflammation in type 1 diabetes. Little is known about the immune phenotype of islet ECs that might shape their m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7026631813e3a569f21f4119dc93beb
https://doi.org/10.4049/jimmunol.181.9.6109
https://doi.org/10.4049/jimmunol.181.9.6109
Publikováno v:
Diabetes. 55:1004-1010
Statins, the widely used inhibitors of cholesterol biosynthesis, also have immunomodulatory properties. Statins have recently been shown to have beneficial prophylactic and therapeutic effects in actively induced, short-term animal models of the auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff448d6ff451b6220bd054ef85185db
https://doi.org/10.2337/diabetes.55.04.06.db05-1261
https://doi.org/10.2337/diabetes.55.04.06.db05-1261
Akademický článek
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Autor:
Wayne Hall, Louisa K. James, Liliana G. Petrich de Marquesini, Jennifer S. Allen, Sally Thrower, Kate Green, Florence Susan Wong, S. Brown, Colin M. Dayan, B. Lozanoska-Ochser, Sefina Arif, Mark Peakman, C. Van-Krinks
Publikováno v:
Clinical and experimental immunology. 155(2)
Summary Immunotherapeutic strategies under consideration for type 1 diabetes include modification of the autoimmune response through antigen-specific routes. Administration of short peptides representing T cell epitopes targeted by patients with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d957c0ef2eb07c8263ac6705aa3d57
https://pubmed.ncbi.nlm.nih.gov/19040615
https://pubmed.ncbi.nlm.nih.gov/19040615
Akademický článek
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Autor:
P Cavallo Perin, Nigel Klein, Enrica Favaro, A. Chiaravalli, Giovanni Camussi, Guo Cai Huang, Pier Giulio Conaldi, Mark Peakman, B. Lozanoska-Ochser, Antonella Bottelli, Maria M. Zanone, Elena Ferioli
Publikováno v:
Diabetologia. 48(12)
Studies on the biology of the microvascular endothelial cells (MECs) that surround and penetrate the pancreatic islets are hampered by difficulties in isolating and culturing large numbers of pure cells. We aimed to morphologically and functionally c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858d3a406ac46c8cfcc023c8d531df95
https://pubmed.ncbi.nlm.nih.gov/16292462
https://pubmed.ncbi.nlm.nih.gov/16292462