Zobrazeno 1 - 10
of 181
pro vyhledávání: '"B. Lovejoy"'
Autor:
Henry B. Lovejoy
This Atlantic world history centers on the life of Juan Nepomuceno Prieto (c. 1773–c. 1835), a member of the West African Yoruba people enslaved and taken to Havana during the era of the Atlantic slave trade. Richly situating Prieto's story within
Autor:
Marcela Cespedes, Kelly R. Jacobs, Paul Maruff, Alan Rembach, Christopher J. Fowler, Brett Trounson, Kelly K. Pertile, Rebecca L. Rumble, Stephanie R. Rainey-Smithe, Christopher C. Rowe, Victor L. Villemagne, Pierrick Bourgeat, Chai K. Lim, Pratishtha Chatterjee, Ralph N. Martins, Arne Ittner, Colin L. Masters, James D. Doecke, Gilles J. Guillemin, David B. Lovejoy
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105783- (2022)
Increasing evidence suggests that kynurenine pathway (KP) dyshomeostasis may promote disease progression in dementia. Studies in Alzheimer's disease (AD) patients confirm KP dyshomeostasis in plasma and cerebrospinal fluid (CSF) which correlates with
Externí odkaz:
https://doaj.org/article/75df2cb1e7904b2c830ffb9d9588ebf8
Autor:
Yanjie Liu, Wendie Wang, Dongya Zhang, Yajing Sun, Fangzhou Li, Meng Zheng, David B. Lovejoy, Yan Zou, Bingyang Shi
Publikováno v:
Exploration, Vol 2, Iss 4, Pp n/a-n/a (2022)
Abstract Glioblastoma (GBM) is a central nervous system tumor with poor prognosis due to the rapid development of resistance to mono chemotherapy and poor brain targeted delivery. Chemoimmunotherapy (CIT) combines chemotherapy drugs with activators o
Externí odkaz:
https://doaj.org/article/76e6c52a9518490fb0d23b2c73e63106
Autor:
Benjamin Heng, Ayse A. Bilgin, David B. Lovejoy, Vanessa X. Tan, Heloisa H. Milioli, Laurence Gluch, Sonia Bustamante, Tharani Sabaretnam, Pablo Moscato, Chai K. Lim, Gilles J. Guillemin
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background Immunotherapy has recently been proposed as a promising treatment to stop breast cancer (BrCa) progression and metastasis. However, there has been limited success in the treatment of BrCa with immune checkpoint inhibitors. This im
Externí odkaz:
https://doaj.org/article/2339ab5edf5e4945b152f4b86d3c26f6
Autor:
Pratishtha Chatterjee, Henrik Zetterberg, Kathryn Goozee, Chai K. Lim, Kelly R. Jacobs, Nicholas J. Ashton, Abdul Hye, Steve Pedrini, Hamid R. Sohrabi, Tejal Shah, Prita R. Asih, Preeti Dave, Kaikai Shen, Kevin Taddei, David B. Lovejoy, Gilles J. Guillemin, Kaj Blennow, Ralph N. Martins
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background Blood markers indicative of neurodegeneration (neurofilament light chain; NFL), Alzheimer’s disease amyloid pathology (amyloid-β; Aβ), and neuroinflammation (kynurenine pathway; KP metabolites) have been investigated independe
Externí odkaz:
https://doaj.org/article/e876417f779b424199b53d555843b257
Autor:
Kelly R Jacobs, David B Lovejoy
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 12, Pp 2073-2076 (2018)
Chronic induction of the kynurenine pathway (KP) contributes to neuroinflammation by producing the excitotoxin quinolinic acid (QUIN). This has led to significant interest in the development of inhibitors of this pathway, particularly in the context
Externí odkaz:
https://doaj.org/article/93618dbe80e8494d8a1ab4d5f9a60c6a
Publikováno v:
Journal of the Royal Statistical Society Series A: Statistics in Society. 185:1247-1270
Intra-African conflicts during the collapse of the kingdom of Oyo from 1817 to 1836 resulted in the enslavement of an estimated 121,000 people who were then transported to coastal ports via complex trade networks and loaded onto slave ships destined
Autor:
Edward A. Alpers, Colleen E. Kriger, Paul E. Lovejoy, Walter Hawthorne, Matthew S. Hopper, Henry B. Lovejoy, Mariana P. Candido, John K. Thornton, Ghislaine Lydon
Publikováno v:
History in Africa. 48:9-34
Regionalizing pre-colonial Africa aids in the collection and interpretation of primary sources as data for further analysis. This article includes a map with six broad regions and 34 sub-regions, which form a controlled vocabulary within which resear