Zobrazeno 1 - 10
of 117
pro vyhledávání: '"B. Leitão"'
Autor:
Alexandre B. Leitão, Ramesh Arunkumar, Jonathan P. Day, Nancy Hanna, Aarathi Devi, Matthew P. Hayes, Francis M. Jiggins
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Innate immune responses can be activated by pathogen-associated molecular patterns (PAMPs), danger signals released by damaged tissues, or the absence of self-molecules that inhibit immunity. As PAMPs are typically conserved acros
Externí odkaz:
https://doaj.org/article/de39d1abcbb54e31971b339b22f03e6a
Publikováno v:
Cadernos de Saúde, Vol 6, Iss Especial.1 (2013)
Externí odkaz:
https://doaj.org/article/dbb7f02cd37f42628c7f4aeb2854e6c2
Publikováno v:
Cadernos de Saúde, Vol 6, Iss Especial.1 (2013)
Externí odkaz:
https://doaj.org/article/0c91b694a8c34158a23326afb177a00c
Autor:
Shuyu Olivia Zhou, Ramesh Arunkumar, Amina Irfan, Shuai Dominique Ding, Alexandre B Leitão, Francis M Jiggins
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011729 (2024)
Both constitutive and inducible immune mechanisms are employed by hosts for defense against infection. Constitutive immunity allows for a faster response, but it comes with an associated cost that is always present. This trade-off between speed and f
Externí odkaz:
https://doaj.org/article/a8971a707b9c48c3b49d8c2b779cbcff
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Parasites reduce the fitness of their hosts, and different causes of this damage have fundamentally different consequences for the evolution of immune defences. Damage to the host may result from the parasite directly harming its host, often due to t
Externí odkaz:
https://doaj.org/article/ca842891ed0a4d0abdcd80ded14960f0
Autor:
Priscila Bellaver, Larissa Schneider, Ariell F. Schaeffer, Lilian Rodrigues Henrique, Joíza Lins Camargo, Fernando Gerchman, Cristiane B. Leitão, Tatiana H. Rech
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18554- (2023)
Background: Diabetes mellitus (DM) is not associated with increased mortality in critically ill patients, a phenomenon known as the “diabetes paradox”. However, DM is a risk factor for increased mortality in patients with COVID-19. This study aim
Externí odkaz:
https://doaj.org/article/5dc88211948144fea04645db3be8fb6d
Autor:
Lana C. Pinto, Dimitris V. Rados, Luciana R. Remonti, Marina V. Viana, Cristiane B. Leitão, Jorge L. Gross
Publikováno v:
Archives of Endocrinology and Metabolism, Vol 66, Iss 1, Pp 68-76 (2022)
ABSTRACT The lowest dosage of empagliflozin (10 mg) showed similar benefits on glycated hemoglobin (HbA1c) level, body weight, blood pressure, and total and cardiovascular mortality in comparison with the highest available dose (25 mg) in the EMPAREG
Externí odkaz:
https://doaj.org/article/9cbcb669a72e4f4984a41e7dca357787
Publikováno v:
Endocrine. 80:511-519
Autor:
Alexandre B Leitão, Ramesh Arunkumar, Jonathan P Day, Emma M Geldman, Ismaël Morin-Poulard, Michèle Crozatier, Francis M Jiggins
Publikováno v:
eLife, Vol 9 (2020)
Organisms rely on inducible and constitutive immune defences to combat infection. Constitutive immunity enables a rapid response to infection but may carry a cost for uninfected individuals, leading to the prediction that it will be favoured when inf
Externí odkaz:
https://doaj.org/article/b00a684d2c534fdbbc21d8b55e2bbd35
Publikováno v:
Journal of Paediatrics and Child Health.