Zobrazeno 1 - 10
of 1 874
pro vyhledávání: '"B. L. de Groot"'
Autor:
Christian Griesinger, Stefan Becker, Artur Mazur, B. L. de Groot, Ashok K. Rout, Colin A. Smith, Donghan Lee
Publikováno v:
Journal of Biomolecular Nmr
Journal of Biomolecular NMR
Journal of Biomolecular NMR
Nuclear magnetic resonance (NMR) has the unique advantage of elucidating the structure and dynamics of biomolecules in solution at physiological temperatures, where they are in constant movement on timescales from picoseconds to milliseconds. Such mo
Autor:
B. L. de Groot, David L. Mobley, Gary Tresadern, Yuriy Khalak, Hannah Magdalena Baumann, Matteo Aldeghi, Vytautas Gapsys
Publikováno v:
Chemical Science
The recent advances in relative protein–ligand binding free energy calculations have shown the value of alchemical methods in drug discovery. Accurately assessing absolute binding free energies, although highly desired, remains a challenging endeav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6bbfdd845229534faa0443c059071e
https://doi.org/10.26434/chemrxiv-2021-rxxbb
https://doi.org/10.26434/chemrxiv-2021-rxxbb
Publikováno v:
From Protein Structure to Function with Bioinformatics ISBN: 9789402410679
From Protein Structure to Function with Bioinformatics ISBN: 9781402090578
From Protein Structure to Function with Bioinformatics
From protein structure to function with bioinformatics
From Protein Structure to Function with Bioinformatics ISBN: 9781402090578
From Protein Structure to Function with Bioinformatics
From protein structure to function with bioinformatics
Understanding protein function requires detailed knowledge about protein dynamics , i.e. the different conformational states the system can adopt. Despite substantial experimental progress, simulation techniques such as molecular dynamics (MD) curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af07340003b73bbd987abafa6217625
https://doi.org/10.1007/978-94-024-1069-3_12
https://doi.org/10.1007/978-94-024-1069-3_12
Autor:
Marc A. Vos, Bart Kok, Gudrun Antoons, Mjc Houtman, B. L. de Groot, Anna Stary, Tab Van Veen, T Opthof, Jdm Beekman, MB Rook, Marcel A.G. van der Heyden, T. P. De Boer, L Nalos
Publikováno v:
British Journal of Pharmacology. 159:1532-1541
Background and purpose: Pentamidine is a drug used in treatment of protozoal infections. Pentamidine treatment may cause sudden cardiac death by provoking cardiac arrhythmias associated with QTc prolongation and U-wave alterations. This proarrhythmic
Autor:
Chen, Siman1 (AUTHOR), Ma, Xiaoqian2 (AUTHOR), Liu, Yukai1 (AUTHOR), Zhong, Zhiqi3 (AUTHOR), Wei, Chunyan1 (AUTHOR), Li, Mingqing1,4 (AUTHOR) mqli@fudan.edu.cn, Zhu, Xiaoyong1,4 (AUTHOR) zhuxiaoyong@fudan.edu.cn
Publikováno v:
Advanced Science. 10/16/2024, Vol. 11 Issue 38, p1-17. 17p.
Autor:
Ding, Shibiao1 (AUTHOR), Cui, Jinyu2 (AUTHOR), Yan, Luning2 (AUTHOR), Ru, Chuhui2 (AUTHOR), He, Fei2 (AUTHOR), Chen, Aifeng2 (AUTHOR) zj_djcc@163.com
Publikováno v:
Clinical Respiratory Journal. Aug2024, Vol. 18 Issue 8, p1-11. 11p.
Autor:
Dimitrios Fotiadis, Andreas D. Schenk, Per Kjellbom, B. L. de Groot, Thomas Braun, Urban Johanson, Wanda Kukulski, Andreas Engel
Publikováno v:
Journal of Molecular Biology. 350:611-616
SoPIP2;1 is one of the major integral proteins in spinach leaf plasma membranes. In the Xenopus oocyte expression system its water channel activity is regulated by phosphorylation at the C terminus and in the first cytosolic loop. To assess its struc
Autor:
Hervé W. Rémigy, Ansgar Philippsen, Paul J.L. Werten, Helmut Grubmüller, B. L. de Groot, Henning Stahlberg, Dimitrios Fotiadis, Andreas Engel
Publikováno v:
FEBS Letters
Structural information on membrane proteins is sparse, yet they represent an important class of proteins that is encoded by about 30% of all genes. Progress has primarily been achieved with bacterial proteins, but efforts to solve the structure of eu
Autor:
Lyu B; Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Binhai New City, Fuzhou, 350207, China.; Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, 117576, Singapore., Jiang J; Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore, 117576, Singapore., Jiang Z; Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University, Binhai New City, Fuzhou, 350207, China.; Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China.; Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300072, China.
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Oct; Vol. 20 (40), pp. e2402822. Date of Electronic Publication: 2024 Jun 05.
Autor:
Palmisano VF; Department of Chemistry, Universidad Autónoma de Madrid, 28049, Madrid, Spain.; Theoretical Chemistry Group, Zernike Institute for Advanced Materials, University of Groningen, 9747 AG, Groningen, The Netherlands., Anguita-Ortiz N; Department of Chemistry, Universidad Autónoma de Madrid, 28049, Madrid, Spain., Faraji S; Theoretical Chemistry Group, Zernike Institute for Advanced Materials, University of Groningen, 9747 AG, Groningen, The Netherlands., Nogueira JJ; Department of Chemistry, Universidad Autónoma de Madrid, 28049, Madrid, Spain.; IADCHEM, Institute for Advanced Research in Chemistry, Universidad Autónoma de Madrid, 28049, Madrid, Spain.
Publikováno v:
Chemphyschem : a European journal of chemical physics and physical chemistry [Chemphyschem] 2024 Aug 19; Vol. 25 (16), pp. e202400162. Date of Electronic Publication: 2024 Jul 17.