Zobrazeno 1 - 9
of 9
pro vyhledávání: '"B. L. Holt"'
Publikováno v:
Journal of Pharmacy and Pharmacology. 47:85-88
This randomized, four-way crossover study in 16 healthy subjects compared the effects of cimetidine 800 mg, ranitidine 300 mg and omeprazole 40 mg against placebo given daily after breakfast for seven days on the pharmacokinetics of a single oral dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1270d84cd045337dc0433b931de9608
https://doi.org/10.1111/j.2042-7158.1995.tb05740.x
https://doi.org/10.1111/j.2042-7158.1995.tb05740.x
Autor:
James Cassidy, B. L. Holt, Malcolm Rowland, Vivian A. John, S. Toon, Bret Berner, Keith K. H. Chan
Publikováno v:
Pharmaceutical Research. 10:126-129
The buccal delivery of the nonsteroidal antiinflammatory drug, diclofenac sodium (Voltaren), from a prototype hydrogel was studied in man in a randomized crossover design of buccal delivery and i.v. infusion. After a 30-min delay, plasma levels of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd11d9b38e15ba5d62fb7437c5aa22f3
https://doi.org/10.1023/a:1018941517355
https://doi.org/10.1023/a:1018941517355
Publikováno v:
British Journal of Clinical Pharmacology. 30:743-750
1. The potential interaction between racemic warfarin given as a 25 mg single oral dose and chronically administered ketorolac was studied in 12 young healthy male volunteers. 2. Ketorolac produced no major change in the pharmacokinetics of (R)- or (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d9eb5249015812a28ecec0b092abf3
https://doi.org/10.1111/j.1365-2125.1990.tb03845.x
https://doi.org/10.1111/j.1365-2125.1990.tb03845.x
Autor:
B. L. Holt, Stephen J. Langley, B. Delalleau, C. Salvadori, Malcolm Rowland, F. G. P. Mullins, S. Toon, M. S. Halliday
Publikováno v:
Psychopharmacology. 101:226-232
To assess if any pharmacokinetic or pharmacodynamic interaction at steady-state occurs between the new antidepressant tianeptine and a benzodiazepine (oxazepam) following multiple oral dosing of both drugs, 12 healthy male volunteers entered a balanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d9399900fe04972e09ac339d454dd5
https://doi.org/10.1007/bf02244131
https://doi.org/10.1007/bf02244131
Autor:
S. S. Preisig-Flückiger, B. L. Holt, John M. Kovarik, Y. Üresin, P. W. Lücker, E A Mueller, S. Hensel
Publikováno v:
Journal of clinical pharmacology. 37(11)
Valspodar is a cyclosporine D analog used as a chemotherapy adjunct for modifying multidrug resistance. Two studies were sequentially performed to select an optimal oral formulation and to characterize selected aspects of its clinical pharmacokinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8aff1c5409ef9bfe98f40eccf6336b
https://pubmed.ncbi.nlm.nih.gov/9505992
https://pubmed.ncbi.nlm.nih.gov/9505992
Publikováno v:
European Journal of Clinical Pharmacology. 42
We have studied the comparative abilities of the prothrombin time and factor VII clotting activity, measured using a chromogenic assay, to detect drug interactions with warfarin. Pharmacokinetic and pharmacodynamic data were collected from studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f66992ab2423cd07f9d7c4b534728f2
https://doi.org/10.1007/bf00265930
https://doi.org/10.1007/bf00265930
Publikováno v:
British journal of anaesthesia. 68(3)
Pregnanolone emulsion was administered i.v. to 13 healthy male volunteers to assess its potential as an agent for i.v. induction of general anaesthesia and to establish a pharmacokinetic profile at two doses. Each subject received 0.5 mg kg-1, 0.75 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0652ffd9aaf7624b84693595ba5206
https://pubmed.ncbi.nlm.nih.gov/1547051
https://pubmed.ncbi.nlm.nih.gov/1547051
Publikováno v:
Survey of Anesthesiology. 36:343
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e46042d64ea4a087cd9769a6eff39e3b
https://doi.org/10.1097/00132586-199212000-00007
https://doi.org/10.1097/00132586-199212000-00007
Autor:
Josephine Lim, Jeffrey W. Meehan, Amin A. Nomeir, B. L. Holt, Paul Glue, Chin-Chung Lin, Pascale Reidenberg, Christopher Banfield, Robert D. Colucci, Melton B. Affrime, Sudhakar Pai
Publikováno v:
Scopus-Elsevier
To assess the possible interaction between lamotrigine and felbamate, a double-blind, randomized, placebo-controlled, two-way crossover study was conducted in 21 healthy male volunteers. Volunteers were given lamotrigine (100 mg every 12 hours) and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84bd93de0cf4a5c62da2ced89920ea66
http://www.scopus.com/inward/record.url?eid=2-s2.0-9344243509&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-9344243509&partnerID=MN8TOARS
