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Hematopoietic growth factors and treatment of testicular cancer: biological interactions, routine use and dose-intensive chemotherapy

Autor: Hans-Joachim Schmoll, Carsten Bokemeyer, H. Köhne, B. Kynast, Hermann Einsele, Markus A. Kuczyk

Publikováno v: Annals of hematology. 72(1)

With the use of aggressive cis-platinum-based combination chemotherapy the majority of patients with metastatic testicular cancer will be cured. Hematopoietic growth factors (HGFs), particularly G- and GM-CSF, have been investigated for the treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2ccc282e82075f98fb937992ecbfc6
https://pubmed.ncbi.nlm.nih.gov/8605273

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Comparison of 5 vs 10 micrograms/kg per day of GM-CSF following dose-intensified chemotherapy with cisplatin, etoposide, and ifosfamide in patients with advanced testicular cancer

Autor: Hans-Joachim Schmoll, Helmut Ostermann, U. Räth, B. Kynast, Jörg Beyer, Carsten Bokemeyer, H. Poliwoda, Bernd Metzner, H J Illiger, Michael Kneba

Publikováno v: Annals of hematology. 67(2)

Despite the increasing use of granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment of chemotherapy-induced neutropenia, few studies have focused on the activity and toxicity of the different clinically used dosages of GM-CSF. F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d6c74cae90af182dc90af93b0d6be2
https://pubmed.ncbi.nlm.nih.gov/8347733

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Determination of a fragment of the c-erbB-2 translational product p185 in serum of breast cancer patients

Autor: H. J. Schmoll, Alfred Schauer, Barbara Zoll, L. Binder, B. Kynast, D. Marx, M. Oellerich

Publikováno v: Journal of cancer research and clinical oncology. 119(5)

Concentrations of a fragment of the c-erbB-2 translational product (p185 fragment) were measured in serum of 70 breast cancer patients, 19 healthy blood donors, and 18 pregnant women using a heterogenic enzyme immunoassay. The serum concentrations of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e709ec7b065ee192c39d5345a64d0bd0
https://pubmed.ncbi.nlm.nih.gov/8095050

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Alterations of the c-erbB2 gene in human breast cancer

Autor: Alfred Schauer, Barbara Zoll, B Corell, B Kynast, D. Marx, G. Fischer

Publikováno v: Journal of cancer research and clinical oncology. 118(6)

DNA amplification, RNA overexpression and p185 protein expression of the c-erbB2 oncogene were investigated in 109 cases of breast cancer with the aim of evaluating any correlation between the different methods. A correlation between Southern blottin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e726c05e31c0b925a851b03f1ffd5cb7
https://pubmed.ncbi.nlm.nih.gov/1352298

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