Ein schneller Weg zur Enantiomerentrennung

Autor: P. Piras, B. Koppenhoefer, C. Roussel, R. Behnisch

Publikováno v: Nachrichten aus Chemie, Technik und Laboratorium. 41:340-344

Der aktuelle Trend zu enantiomerenreinen Wirkstoffen hat eine weltweite Suche nach effizienten Methoden zur chromatographischen Trennung von Enantiomeren ausgelost. Am Beispiel von Naproxen - einem nichtsteroidalen Entzundungshemmer mit einem Weltmar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84e6087ddd4200595d6a56b579076809
https://doi.org/10.1002/nadc.19930410314

ChemInform Abstract: A Useful Route to Both Enantiomers of 1-Amino-2-alkanols: Synthesis of 1-Amino-3-methyl-2-butanol from Valine

Autor: B. Koppenhoefer, A. Waechtler, U. Trettin

Publikováno v: ChemInform. 26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27480fa3739181bf5fd104b72458bd16
https://doi.org/10.1002/chin.199518072

Separation of enantiomers of drugs by capillary electrophoresis. V. Hydroxypropyl-alpha-cyclodextrin as chiral solvating agent

Autor: B, Koppenhoefer, U, Epperlein, R, Schlunk, X, Zhu, B, Lin

Publikováno v: Journal of chromatography. A. 793(1)

In an extended chiral drug screening program, enantioseparation of 86 racemic drugs was tested with hydroxypropyl-alpha-cyclodextrin as chiral solvating agent (CSA). A total of 34 drugs out of 86 could be resolved in this straightforward approach. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b6f001ebdcf88e71e908c98e99e97f6
https://pubmed.ncbi.nlm.nih.gov/9468655

CD40L modulates CD4 ⁺ T-cell activation through receptor for activated C kinase 1.

Autor: van Os BW; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., Vos WG; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., Bosmans LA; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., van Tiel CM; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., Toom MD; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., Beckers L; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., Admiraal M; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands., Hoeksema MA; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., de Winther MP; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands., Lutgens E; Department of Medical Biochemistry, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands.; Amsterdam Immunity and Infection, Inflammatory diseases, Amsterdam, the Netherlands.; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-Universität, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA.

Publikováno v: European journal of immunology [Eur J Immunol] 2023 Dec; Vol. 53 (12), pp. e2350520. Date of Electronic Publication: 2023 Nov 20.

Chiral recognition in the resolution of enantiomers by GLC

Autor: Ernst Bayer, B. Koppenhoefer

Publikováno v: Chromatographia. 19:123-130

Chiral recognition of many enantiomeric solutes by a chiral amide stationary phase is based mainly on hydrogen bonding. A chiral-recognition-factor CHI is proposed, given by the difference of the enthalpy change in the enantiomer discrimination, stan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::830c487cd97490df45ec9c7b3fd1d7d0
https://doi.org/10.1007/bf02687727