Zobrazeno 1 - 10
of 171
pro vyhledávání: '"B. Kopnin"'
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 2, Pp 97-105 (2024)
Introduction. Lung and colorectal cancers are the most common cancer types, characterized by a poor prognosis. Tumor progression is also caused by the aberrant activity of intercellular signaling pathways, which can arise due to mutations in genes en
Externí odkaz:
https://doaj.org/article/05fd5096324c4b0e9fc2e2a2192d8419
Autor:
A. R. Galembikova, P. D. Dunaev, T. V. Ivoilova, A. I. Gilyazova, A. E. Galyautdinova, E. G. Mikheeva, S. S. Zykova, N. M. Igidov, P. B. Kopnin, S. V. Boichuk
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 2, Pp 130-146 (2024)
Introduction. Microtubules are highly dynamic polymers of α, β-tubulin dimers involves in a broad spectrum of the processes, such as intracellular transport and cell proliferation. This makes them an attractive molecular target for anti-cancer ther
Externí odkaz:
https://doaj.org/article/940816d67b9d4f18b3944d3e8d2894b2
Publikováno v:
EJC Supplements, Vol 13, Iss 1, p 48 (2015)
Malignant tumors consist not only of neoplastic cells, but also of various normal cells, for example fibroblasts, macrophages or endothelial cells. These normal cells stand under constant pressure of transformed cells, regulating their properties and
Externí odkaz:
https://doaj.org/article/9da5d4bdecbe4bbe868559d8dab76268
Autor:
A. R. Galembikova, P. D. Dunaev, F. F. Bikinieva, I. G. Mustafin, P. B. Kopnin, S. S. Zykova, F. I. Mukhutdinova, E. A. Sarbazyan, S. V. Boichuk
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 3, Pp 59-71 (2023)
Introduction. Mitotic poisoning agents (MPAs) affecting the dynamic state of the microtubules, are the well-known and effective chemotherapeutic agents. Mitotic poisoning agents are binding to the microtubules, and thereby interfere with tubulin poly
Externí odkaz:
https://doaj.org/article/a26cff9aade94663bffd2aa69677a796
Autor:
Gleb O. Skryabin, Andrei V. Komelkov, Kirill I. Zhordania, Dmitry V. Bagrov, Adel D. Enikeev, Sergey A. Galetsky, Anastasiia A. Beliaeva, Pavel B. Kopnin, Andey V. Moiseenko, Alexey M. Senkovenko, Elena M. Tchevkina
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 902 (2024)
Extracellular vesicles (EVs) are of growing interest in the context of screening for highly informative cancer markers. We have previously shown that uterine aspirate EVs (UA EVs) are a promising source of ovarian cancer (OC) diagnostic markers. In t
Externí odkaz:
https://doaj.org/article/8b5e65c7a23949c8884e539fb989c5ba
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 2, Pp 17-29 (2023)
Gastrointestinal stromal tumors (GIST) are most common mesenchymal tumors in gastrointestinal tract which originate from interstitial cells of Cajal and characterized by the mutations in the KIT or PDGFRA tyrosine kinase receptors. Thus, the common t
Externí odkaz:
https://doaj.org/article/8ff48add39c64db19b72798e0c81ed22
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The cytoplasmic actin isoforms (β- and γ-actins) contribute greatly to cellular processes such as cel-cell and cell-matrix interactions, as well as cell polarization, motility and division. Distinct isoforms modulations are linked to serious pathol
Externí odkaz:
https://doaj.org/article/daccd078691b4c4e9f15617f2db9bd0e
Autor:
Voutilainen, N. B. Kopnin J.
Charge transport in a high-transmission single-mode long SINIS junction (S stands for superconductor, I is an insulator, and N is a normal metal) is considered in the limit of low bias voltages and low temperatures. The kinetic equation for the quasi
Externí odkaz:
http://arxiv.org/abs/cond-mat/0612514
Autor:
O. V. Kovaleva, P. A. Podlesnaya, M. V. Vasileva, P. B. Kopnin, A. S. Balkin, A. O. Plotnikov, N. E. Kushlinskii, A. N. Gratchev
Publikováno v:
Doklady Biochemistry and Biophysics. 507:312-317
Publikováno v:
Biochemistry (Moscow). 87:1199-1205
Lung and colorectal cancers are the most common types of cancer characterized by a poor prognosis and a high mortality rate. Mutations in the genes encoding components of the main intra- and extracellular signaling pathways, in particular the NOTCH1