Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial

Autor: Matthew C Winter, Daniel Rea, Jacinta Abraham, Olga Oikonomidou, Iain R. Macpherson, David Cameron, Jeremy P Braybrooke, Sarah Kernaghan, Andrew M Wardley, Heidrun Gevensleben, Laura Moretti, Mark Tuthill, Katrina Randle, Peter Stephens, A Ring, Mike Hubank, Judith M Bliss, Rebecca Roylance, Abeer M Shaaban, Hannah Bye, Lucy Kilburn, Sue Martin, B Kingston, Katie Wilkinson, Nicholas C. Turner, Claire Snowdon, Ros Cutts, Richard D. Baird

Publikováno v: C Turner, N, Kingston, B, S Kilburn, L, Kernaghan, S, M Wardley, A, R Macpherson, I, D Baird, R, Roylance, R, Stephens, P, Oikonomidou, O, P Braybrooke, J, Tuthill, M, Abraham, J, C Winter, M, Bye, H, Hubank, M, Gevensleben, H, Cutts, R, Snowdon, C, Rea, D, Cameron, D A, Shaaban, A, Randle, K, Martin, S, Wilkinson, K, Moretti, L, Bliss, J M & Ring, A 2020, ' Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial ', The Lancet Oncology, vol. 21, no. 10, pp. 1296-1308 . https://doi.org/10.1016/S1470-2045(20)30444-7

BACKGROUND: Circulating tumour DNA (ctDNA) testing might provide a current assessment of the genomic profile of advanced cancer, without the need to repeat tumour biopsy. We aimed to assess the accuracy of ctDNA testing in advanced breast cancer and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a5a7ae2a2af9e5ba7c16e614105e61
https://doi.org/10.1016/s1470-2045(20)30444-7

Basic Science * 208. Stem Cell Factor Expression is Increased in the Skin of Patients with Systemic Sclerosis and Promotes Proliferation and Migration of Fibroblasts in vitro

Autor: S. Karrar, X. Shiwen, J. Nikotorowicz-Buniak, D. J. Abraham, C. Denton, R. Stratton, R. Bayley, K. A. Kite, E. Clay, J. P. Smith, G. D. Kitas, C. Buckley, S. P. Young, L. Ye, L. Zhang, J. Goodall, H. Gaston, H. Xu, P. M. Lutalo, Y. Zhao, L. Meng Choong, S. Sangle, J. Spencer, D. D'Cruz, O. J. Rysnik, K. McHugh, P. Bowness, L. Rump-Goodrich, D. Mattey, O. Kehoe, J. Middleton, A. Cartwright, C. Schmutz, A. Askari, D. H. Gardner, L. E. Jeffery, K. Raza, D. M. Sansom, M. Fitzpatrick, G. Wallace, S. Young, J. Shaw, H. Hatano, A. Cauli, J. L. Giles, A. Mathieu, S. Kollnberger, S. Webster, L. Ellis, L. M. O'Brien, T. J. Fitzmaurice, A. Nazeer Moideen, L. Evans, L. Osgood, A. Williams, S. Jones, C. Thomas, V. O'Donnell, M. Nowell, L. Ouboussad, S. Savic, L. J. Dickie, J. Hintze, C. H. Wong, G. P. Cook, M. Buch, P. Emery, M. F. McDermott, S. A. Hardcastle, C. L. Gregson, K. Deere, G. Davey Smith, P. Dieppe, J. H. Tobias, E. Dennison, M. Edwards, J. Bennett, D. Coggon, K. Palmer, C. Cooper, D. McWilliams, A. Young, P. D. Kiely, D. Walsh, H. J. Taylor, I. Harding, J. Hutchinson, I. Nelson, A. Blom, J. Tobias, E. Clark, J. Parker, M. Bukhari, K. Jayakumar, P. Kiely, J. Diffin, M. Lunt, T. Marshall, J. Chipping, D. Symmons, S. Verstappen, J. Bluett, J. Bowes, P. Ho, N. McHugh, D. Buden, O. Fitzgerald, A. Barton, J. R. Glossop, N. B. Nixon, R. D. Emes, P. T. Dawes, W. E. Farrell, D. L. Mattey, I. C. Scott, S. Steer, S. Seegobin, A. M. Hinks, S. Eyre, A. Morgan, A. G. Wilson, L. Hocking, P. Wordsworth, J. Worthington, A. Cope, C. M. Lewis, S. Guerra, B. A. Ahmed, D. Abraham, C. Fonseca, J. Robinson, J. Taylor, L. Haroon Rashid, E. Flynn, J. Isaacs, J. H. Barrett, B. Kingston, M. Ahmed, J. R. Kirwan, R. Marshall, K. Chapman, R. Pearson, C. Heycock, C. Kelly, M. Rynne, V. Saravanan, J. Hamilton, A. Saeed, R. Coughlan, J. J. Carey, Z. Farah, W. Matthews, C. Bell, S. Petford, L.-M. Tibbetts, K. M. J. Douglas, W. Holden, J. Ledingham, M. Fletcher, R. Winfield, Z. Price, K. Mackay, C. Dixon, R. Oppong, S. Jowett, E. Nicholls, D. Whitehurst, S. Hill, A. Hammond, E. Hay, K. Dziedzic, C. Righetti, M. Lebmeier, V. L. Manning, M. Hurley, D. L. Scott, E. Choy, L. Bearne, E. Nikiphorou, S. Morris, D. James, E. C. Wong, J. Long, A. Fletcher, S. Holmes, P. Hockey, M. Abbas, C. Chattopadhyay, J. Flint, M. Gayed, K. Schreiber, S. Arthanari, M. Nisar, M. Khamashta, C. Gordon, I. Giles, J. Robson, A. Kiran, J. Maskell, N. Arden, A. Hutchings, A. Emin, D. Culliford, B. Dasgupta, W. Hamilton, R. Luqmani, H. Jethwa, D. Rowczenio, H. Trojer, T. Russell, J. Loeffler, P. Hawkins, H. Lachmann, I. Verma, A. Syngle, P. Krishan, N. Garg, S. P. McGowan, D. T. Gerrard, H. Chinoy, W. E. Ollier, R. G. Cooper, J. A. Lamb, L. Taborda, P. Correia Azevedo, D. Isenberg, K. M. Leyland, A. Judge, D. Hunter, D. Hart, M. K. Javaid, M. H. Edwards, A. E. Litwic, K. A. Jameson, D. Deeg, J. Cushnaghan, A. Aihie Sayer, D. Jagannath, C. Parsons, L. Stoppiello, P. Mapp, S. Ashraf, D. Wilson, R. Hill, B. Scammell, C. Wenham, P. Shore, R. Hodgson, A. Grainger, J. Aaron, L. Hordon, P. Conaghan, Y. Bar-Ziv, Y. Beer, Y. Ran, S. Benedict, N. Halperin, M. Drexler, A. Mor, G. Segal, A. Lahad, A. Haim, U. Rath, D. M. Morgensteren, M. Salai, A. Elbaz, V. G. Vasishta, E. Derrett-Smith, R. Hoyles, K. Khan, A. Ezeonyeji, G. Takhar, V. Ong, L. Loughrey, L.-A. Bissell, E. Hensor, G. Abignano, A. Redmond, F. Del Galdo, F. C. Hall, A. Malaviya, S. Baker, A. Furlong, A. Mitchell, A. L. Godfrey, M. Ruddlesden, A. Hadjinicolaou, M. Hughes, T. Moore, N. O'Leary, A. Tracey, H. Ennis, G. Dinsdale, C. Roberts, A. Herrick, C. P. Denton, L. Guillevin, E. Hunsche, D. Rosenberg, B. Schwierin, M. Scott, T. Krieg, M. Anderson, M. Matucci-Cerinic, R. Alade, S. Xu, S. Nihtyanova, K. E. Clark, F. W. K. Tam, R. Unwin, R. J. Stratton, B. Schreiber, C. Seng Edwin Lim, E. Corsiero, N. Sutcliffe, H. Wardemann, C. Pitzalis, M. Bombardieri, H. Tahir, S. Donnelly, M. Greenwood, T. O. Smith, V. Easton, H. Bacon, E. Jerman, K. Armon, F. Poland, A. Macgregor, D. van der Heijde, J. Sieper, D. Elewaut, A. L. Pangan, D. Nguyen, C. Badenhorst, S. Kirby, D. White, A. Harrison, J. A. Garcia, S. Stebbings, J. W. MacKay, S. Aboelmagd, K. Gaffney, A. Deodhar, J. Braun, M. Mack, B. Hsu, T. Gathany, C. Han, R. D. Inman, N. Cooper-Moss, J. Packham, V. Strauss, J. E. Freeston, L. Coates, J. Nam, A. R. Moverley, P. Helliwell, R. Wakefield, P. Mease, R. Fleischmann, J. Wollenhaupt, D. Kielar, F. Woltering, C. Stach, B. Hoepken, T. Arledge, D. Gladman, G. Coteur, A. Kavanaugh, O. Purcaru, I. McInnes, A. B. Gottlieb, L. Puig, P. Rahman, C. Ritchlin, S. Li, Y. Wang, A. Mendelsohn, M. Doyle, W. Tillett, D. Jadon, G. Shaddick, C. Cavill, G. Robinson, R. Sengupta, E. Korendowych, C. de Vries, R. C. Thomas, T. Shuto, N. Busquets-Perez, H. Marzo-Ortega, D. McGonagle, G. Richards, S. Bingham, P. John Hamlin, R. Adshead, S. Cambridge, P. Suppiah, M. Cullinan, A. Nolan, W. M. Thompson, H. R. Mathieson, S. L. Mackie, D. Bryer, M. Krutikov, L. Gray, E. Bruce, A. Keat, W. Innes, R. Pandit, L. Kay, S. Lapshina, L. Myasoutova, S. Erdes, D. Wallis, N. Waldron, I. Thorne, C. Harris, K. Vohra, D. Khinchi, L. Kaur, A. Jones, N. Harrison, D. Harris, T. Jones, J. Rees, A. Bennett, S. Fazal, N. Tugnet, N. Barkham, N. Basu, A. McClean, L. Harper, E. N. Amft, N. Dhaun, R. A. Luqmani, M. A. Little, D. R. Jayne, O. Flossmann, J. McLaren, V. Kumar, D. M. Reid, G. J. Macfarlane, G. Jones, M. Yates, R. A. Watts, L. Igali, C. Mukhtyar, H. Doll, S. Yew, R. Suppiah, P. Hoglund, D. Jayne, K. Westman, W. Win Maw, P. Patil, M. Williams, T. Adizie, D. Christidis, F. Borg, A. Robertson, A. P. Croft, S. Smith, S. Carr, S. Youssouf, A. Salama, C. Pusey, M. Morgan

Publikováno v: Rheumatology. 52:i135-i172

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4274168dcb6af09e716060f4a62004f8
https://doi.org/10.1093/rheumatology/ket195

Computational intelligence methods for the efficient reliability analysis of complex flood defence structures

Autor: Pieter van Gelder, Ben Gouldby, Greer B. Kingston, Mohammadreza Rajabalinejad

Publikováno v: Structural safety, 33(1), 64-73. Elsevier

With the continual rise of sea levels and deterioration of flood defence structures over time, it is no longer appropriate to define a design level of flood protection, but rather, it is necessary to estimate the reliability of flood defences under v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada61ded8fa0c893f15b56dad612ad45
https://doi.org/10.1016/j.strusafe.2010.08.002

VERTICAL MIGRATION OF A MIXED-SPECIESEUGLENA(EUGLENOPHYTA) ASSEMBLAGE INHABITING THE HIGH-INTERTIDAL SANDS OF NYE BEACH, OREGON

Autor: Michael B. Kingston, Jennifer S. Gough

Publikováno v: Journal of Phycology. 45:1021-1029

Comparatively little is known about the vertical migration of the microphytobenthic community forming visible patches on high-energy beaches. We collected surface and cored samples to evaluate the timing and extent of downward migration of a multispe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76a16229a24b09eb35a70a7a79fb9810
https://doi.org/10.1111/j.1529-8817.2009.00748.x

GRAPE PHYLLOXERA EXTERNAL MORPHOLOGY OBSERVATIONS UNDER SCANNING ELECTRON MICROSCOPY

Autor: Paul D. Cooper, Kevin S. Powell, K B Kingston

Publikováno v: Acta Horticulturae. :107-114

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4610f086c04b761192bdb1ecc1c27ad5
https://doi.org/10.17660/actahortic.2007.733.11