Zobrazeno 1 - 10
of 204
pro vyhledávání: '"B. Kaufer"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Porcine cytomegalovirus (PCMV), that is actually a porcine roseolovirus (PRV), is a common herpesvirus in domestic pigs and wild boars. In xenotransplantation, PCMV/PRV has been shown to significantly reduce the survival time of pig kidneys
Externí odkaz:
https://doaj.org/article/6489ae5e1b4b49a7a19686ebd0c25b9d
Autor:
Yu You, Ahmed M. Kheimar, Tereza Vychodil, Lisa Kossak, Mohammad A. Sabsabi, Andelé M. Conradie, Sanjay M. Reddy, Luca D. Bertzbach, Benedikt B. Kaufer
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-8 (2024)
Abstract Marek’s disease virus (MDV) integrates its genome into the telomeres of host chromosomes and causes fatal lymphomas in chickens. This integration is facilitated by telomeric repeat sequences (TMRs) at the ends of the viral genome, and is c
Externí odkaz:
https://doaj.org/article/dbb9de82470d45bb8b74af901a62836e
Autor:
Mohammad A. Sabsabi, Ahmed Kheimar, Yu You, Dominik von La Roche, Sonja Härtle, Thomas W. Göbel, Theresa von Heyl, Benjamin Schusser, Benedikt B. Kaufer
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that causes deadly lymphomas in chickens. In chickens, up to 50% of all peripheral T cells are gamma delta (γδ) T cells. Until now, their role in MDV pathogenesis and tumor for
Externí odkaz:
https://doaj.org/article/0c96e4576b904e06a16d362eecd77b83
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
T cell receptor (TCR) repertoire sequencing has emerged as a powerful tool for understanding the diversity and functionality of T cells within the host immune system. Yet, the chicken TCR repertoire remains poorly understood due to incomplete genome
Externí odkaz:
https://doaj.org/article/20fe5ed6d96c48a8af86d05b829b1605
Autor:
DongHoon Yu, Sabrina Wagner, Martin Schütz, Yeejin Jeon, Mooyoung Seo, Jaeseung Kim, Nadine Brückner, Jintawee Kicuntod, Julia Tillmanns, Christina Wangen, Friedrich Hahn, Benedikt B. Kaufer, Frank Neipel, Jan Eickhoff, Bert Klebl, Kiyean Nam, Manfred Marschall
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 158 (2024)
The repertoire of currently available antiviral drugs spans therapeutic applications against a number of important human pathogens distributed worldwide. These include cases of the pandemic severe acute respiratory coronavirus type 2 (SARS-CoV-2 or C
Externí odkaz:
https://doaj.org/article/bc65e804ec3a43f1ab41539356429fa9
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Marek’s disease virus (MDV), an avian alphaherpesvirus, infects chickens, transforms CD4+ T cells, and induces immunosuppression early during infection. However, the exact mechanisms involved in MDV-induced immunosuppression are yet to be identifie
Externí odkaz:
https://doaj.org/article/8ef9b155eae1450fb46c81651de219ee
Autor:
Laëtitia Trapp-Fragnet, Julia Schermuly, Marina Kohn, Luca D Bertzbach, Florian Pfaff, Caroline Denesvre, Benedikt B Kaufer, Sonja Härtle
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1010006 (2021)
Marek's disease virus (MDV) is an alphaherpesvirus that causes immunosuppression and deadly lymphoma in chickens. Lymphoid organs play a central role in MDV infection in animals. B-cells in the bursa of Fabricius facilitate high levels of MDV replica
Externí odkaz:
https://doaj.org/article/8a68d4424bbf46c2967747934bbdafb5
Autor:
Benjamin E Warner, Michael B Yee, Mingdi Zhang, Rebecca S Hornung, Benedikt B Kaufer, Robert J Visalli, Phillip R Kramer, William F Goins, Paul R Kinchington
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009689 (2021)
Herpes zoster, the result of varicella-zoster virus (VZV) reactivation, is frequently complicated by difficult-to-treat chronic pain states termed postherpetic neuralgia (PHN). While there are no animal models of VZV-induced pain following viral reac
Externí odkaz:
https://doaj.org/article/7914fd3dbf8b4fda9a084c32ac862fb1
Autor:
Shella Gilbert-Girard, Annie Gravel, Vanessa Collin, Darren J Wight, Benedikt B Kaufer, Eros Lazzerini-Denchi, Louis Flamand
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008496 (2020)
Human herpesviruses 6A and 6B (HHV-6A/B) are unique among human herpesviruses in their ability to integrate their genome into host chromosomes. Viral integration occurs at the ends of chromosomes within the host telomeres. The ends of the HHV-6A/B ge
Externí odkaz:
https://doaj.org/article/ca1db6804d90497b9495b8a2c15ed172
Autor:
Jumpei Sato, Shiro Murata, Zhiyuan Yang, Benedikt B. Kaufer, Sotaro Fujisawa, Hikari Seo, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Nikolaus Osterrieder, Mark S. Parcells, Kazuhiko Ohashi
Publikováno v:
Viruses, Vol 14, Iss 2, p 382 (2022)
Marek’s disease virus (MDV) causes malignant lymphoma in chickens (Marek’s disease, MD). Although MD is currently controlled by vaccination, MDV strains have continuously increased in virulence over the recent decades. Polymorphisms in Meq, an MD
Externí odkaz:
https://doaj.org/article/a1ffe3b58e134ddcb289366804dea3ce