Zobrazeno 1 - 10 of 229 pro vyhledávání: '"B. Kapadia"'
1
Akademický článek
A screen for cell envelope stress uncovers an inhibitor of prolipoprotein diacylglyceryl transferase, Lgt, in Escherichia coli
Autor: Kenneth Rachwalski, Sean J. Madden, Nicole Ritchie, Shawn French, Timsy Bhando, Adele Girgis-Gabardo, Megan Tu, Rodion Gordzevich, Rowan Ives, Amelia B.Y. Guo, Jarrod W. Johnson, Yiming Xu, Sharookh B. Kapadia, Jakob Magolan, Eric D. Brown
Publikováno v: iScience, Vol 27, Iss 10, Pp 110894- (2024)
Summary: The increasing prevalence of antibiotic resistance demands the discovery of antibacterial chemical scaffolds with unique mechanisms of action. Phenotypic screening approaches, such as the use of reporters for bacterial cell stress, offer pro
Externí odkaz: https://doaj.org/article/632df03525ba4e1abf66b25ee4e9f31f
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2
Akademický článek
Early plasma angiopoietin-2 is prognostic for ARDS and mortality among critically ill patients with sepsis
Autor: Carrie M. Rosenberger, Katherine D. Wick, Hanjing Zhuo, Nelson Wu, Yue Chen, Sharookh B. Kapadia, Alessander Guimaraes, Diana Chang, David F. Choy, Hubert Chen, Melicent Peck, Kathryn M. Sullivan, Serena Ke, Alejandra Jauregui, Aleksandra Leligdowicz, Pratik Sinha, Antonio D. Gomez, Kirsten N. Kangelaris, Kevin Delucchi, Kathleen D. Liu, Carolyn S. Calfee, Michael A. Matthay, Carolyn M. Hendrickson
Publikováno v: Critical Care, Vol 27, Iss 1, Pp 1-4 (2023)
Abstract Angiopoietin-2 (Ang-2) is associated with vascular endothelial injury and permeability in the acute respiratory distress syndrome (ARDS) and sepsis. Elevated circulating Ang-2 levels may identify critically ill patients with distinct pathobi
Externí odkaz: https://doaj.org/article/bb55343a042743f580ac39a049bd0386
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3
Akademický článek
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling
Autor: Jason A. Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco, Xia Gao, Eugene Kim, Nathan West, Aditi Qamra, Diana Chang, Arindam Chakrabarti, David F. Choy, Alexis J. Combes, Tristan Courau, Gabriela K. Fragiadakis, Arjun Arkal Rao, Arja Ray, Jessica Tsui, Kenneth Hu, Nicholas F. Kuhn, Matthew F. Krummel, David J. Erle, Kirsten Kangelaris, Aartik Sarma, Zoe Lyon, Carolyn S. Calfee, Prescott G. Woodruff, Rajani Ghale, Eran Mick, Ashley Byrne, Beth Shoshana Zha, Charles Langelier, Carolyn M. Hendrickson, Monique G.P. van der Wijst, George C. Hartoularos, Tianna Grant, Raymund Bueno, David S. Lee, John R. Greenland, Yang Sun, Richard Perez, Anton Ogorodnikov, Alyssa Ward, Chun Jimmie Ye, Thiru Ramalingam, Jacqueline M. McBride, Fang Cai, Anastasia Teterina, Min Bao, Larry Tsai, Ivan O. Rosas, Aviv Regev, Sharookh B. Kapadia, Rebecca N. Bauer, Carrie M. Rosenberger, Yumiko Abe-Jones, Michael Adkisson, K. Mark Ansel, Saurabh Asthana, Alexander Beagle, Sharvari Bhide, Cathy Cai, Saharai Caldera, Maria Calvo, Sidney A. Carrillo, Suzanna Chak, Stephanie Christenson, Zachary Collins, Spyros Darmanis, Angela Detweiler, Catherine DeVoe, Walter Eckalbar, Jeremy Giberson, Ana Gonzalez, Gracie Gordon, Paula Hayakawa Serpa, Alejandra Jauregui, Chayse Jones, Serena Ke, Divya Kushnoor, Tasha Lea, Deanna Lee, Aleksandra Leligdowicz, Yale Liu, Salman Mahboob, Lenka Maliskova, Michael Matthay, Elizabeth McCarthy, Priscila Muñoz-Sandoval, Norma Neff, Viet Nguyen, Nishita Nigam, Randy Parada, Maira Phelps, Logan Pierce, Priya Prasad, Sadeed Rashid, Gabriella Reeder, Nicklaus Rodriguez, Bushra Samad, Andrew Schroeder, Cole Shaw, Alan Shen, Austin Sigman, Pratik Sinha, Matthew Spitzer, Sara Sunshine, Kevin Tang, Luz Torres Altamirano, Alexandra Tsitsiklis, Erden Tumurbaatar, Vaibhav Upadhyay, Alexander Whatley, Andrew Willmore, Michael Wilson, Juliane Winkler, Kristine Wong, Kimberly Yee, Michelle Yu, Mingyue Zhou, Wandi S. Zhu
Publikováno v: iScience, Vol 26, Iss 10, Pp 107813- (2023)
Summary: Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with acute lung injury from SARS-CoV-2 or other causes across
Externí odkaz: https://doaj.org/article/9fcf76e7c2d9439cbd17b0a0b7fa8d89
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6
Akademický článek
Unstable Mechanisms of Resistance to Inhibitors of Escherichia coli Lipoprotein Signal Peptidase
Autor: Homer Pantua, Elizabeth Skippington, Marie-Gabrielle Braun, Cameron L. Noland, Jingyu Diao, Yutian Peng, Susan L. Gloor, Donghong Yan, Jing Kang, Anand Kumar Katakam, Janina Reeder, Georgette M. Castanedo, Keira Garland, Laszlo Komuves, Meredith Sagolla, Cary D. Austin, Jeremy Murray, Yiming Xu, Zora Modrusan, Min Xu, Emily J. Hanan, Sharookh B. Kapadia
Publikováno v: mBio, Vol 11, Iss 5 (2020)
ABSTRACT Clinical development of antibiotics with novel mechanisms of action to kill pathogenic bacteria is challenging, in part, due to the inevitable emergence of resistance. A phenomenon of potential clinical importance that is broadly overlooked
Externí odkaz: https://doaj.org/article/ad7dc0127d394ca78d233d455e860331
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9
PARK2 Regulates eIF4B-Driven Lymphomagenesis
Autor: Bandish B. Kapadia, Anirban Roychowdhury, Forum Kayastha, Nahid Nanaji, Ronald B. Gartenhaus
Publikováno v: Molecular Cancer Research. 20:735-748
Patients with high-risk diffuse large B-cell lymphoma have poor outcomes following first-line cyclophosphamide, doxorubicin, vincristine, prednisone, and rituximab (R-CHOP); thus, treatment of this fatal disease remains an area of unmet medical need
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678b26d462fbaa3c53005647538052b8
https://doi.org/10.1158/1541-7786.mcr-21-0729
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