Výsledky vyhledávání - "B. K. Michelsen"

Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings

Autor: Flemming Pociot, Tina Rambrand, Jørn Nerup, B. K. Michelsen, Kjersti S. Rønningen

Publikováno v: Human Genetics. 99:177-185

Reliable genetic and immunological markers are important in the prediction of insulin-dependent diabetes mellitus (IDDM). Since glutamic acid decarboxylase (GAD) is a candidate primary autoantigen, we examined the possible linkage between IDDM and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f12be9fd4819a6793c69341d0b65029
https://doi.org/10.1007/s004390050334

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Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-M(r) autoantibodies

Autor: A. E. Karlsen, W. A. Hagopian, J. S. Petersen, E. Boel, T. Dyrberg, C. E. Grubin, B. K. Michelsen, O. D. Madsen, A. Lernmark

Publikováno v: Diabetes. 41:1355-1359

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0169a00e0e3458bfe454d6160f483a95
https://doi.org/10.2337/diabetes.41.10.1355

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Treatment of an immortalized APC cell line with both cytokines and LPS ensures effective T-cell activation in vitro

Autor: T N, Jørgensen, C, Haase, B K, Michelsen

Publikováno v: Scandinavian journal of immunology. 56(5)

Antigen-presenting cells (APCs) are crucial for the generation of a functional immune response to pathogens. Furthermore, there is abundant evidence for their importance in primary T-cell activation, B-cell maturation and maintenance of an ongoing im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f478a3846ed2d19b7a6e0b63ccde5d74
https://pubmed.ncbi.nlm.nih.gov/12410799

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Diabetes in the Old Order Amish: characterization and heritability analysis of the Amish Family Diabetes Study

Autor: Callum J. Bell, B K Michelsen, Braxton D. Mitchell, Hakan Sakul, P L St Jean, M Gelder Ehm, W. C. Knowler, T.I. Pollin, R Aburomia, Michael J. Wagner, Alan R. Shuldiner, Daniel K. Burns, Wen-Chi Hsueh

Publikováno v: Diabetes care. 23(5)

OBJECTIVE: The Old Order Amish (OOA) are a genetically well-defined closed Caucasian founder population. The Amish Family Diabetes Study was initiated to identify susceptibility genes for type 2 diabetes. This article describes the genetic epidemiolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b13d3e6127687f587a8bbd6f0c1d3ee
https://pubmed.ncbi.nlm.nih.gov/10834415

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Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings. The Danish Study Group of Diabetes in Childhood

Autor: T, Rambrand, F, Pociot, K S, Rønningen, K, Rønningen, J, Nerup, B K, Michelsen

Publikováno v: Human genetics. 99(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eeae3f4693081aff9d17f97a041e4a65
https://pubmed.ncbi.nlm.nih.gov/9048916

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Detection of pancreatic islet 64,000 M(r) autoantigens in insulin-dependent diabetes distinct from glutamate decarboxylase

Autor: T L Delovitch, Michael R. Christie, B K Michelsen, J A Hollands, T J Brown

Publikováno v: The Journal of clinical investigation. 92(1)

Patients with insulin-dependent diabetes (IDDM) possess antibodies to islet proteins of M(r)-64,000. Potential autoantigens of this M(r) include glutamate decarboxylase (GAD) and 65 kD heat shock protein. We have detected two distinct antibody specif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bda671fb255c39f1e6823955c91950a
https://pubmed.ncbi.nlm.nih.gov/8325989

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