Zobrazeno 1 - 10
of 67
pro vyhledávání: '"B. Judkins"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Lisa E. Ranshaw, Tracy Jane Shipley, Suzanne Elaine Keeling, Colin David Eldred, Nicola Mary Aston, B. Judkins, Ed Robinson, Kam Gohil, Naimisha Trivedi, Christopher James Lunniss, Andy Craven
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:137-140
Species specific conversion of the lead PDE4 inhibitor 1 to the quinolone 3 was identified as the major route of metabolism in the cynomolgus monkey. Modification of the template to give the cinnoline 9 retained potency and selectivity, and greatly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb271e1e882da928f3b0ee05c4c9fb31
https://doi.org/10.1016/j.bmcl.2009.11.010
https://doi.org/10.1016/j.bmcl.2009.11.010
Autor:
Joyce Nelson, Kerry Nixon, Stanley C. Gill, James A. Farmer, Mark B. Judkins, Philip M. Zack, Richard Bolin, Daniel W. Drolet, Chris Tucker, Julie Wolf, Raymond A. Bendele
Publikováno v:
Pharmaceutical Research. 17:1503-1510
Purpose. The objective of this study was to determine the pharmacokinetics and safety for NX1838 following injection into the vitreous humor of rhesus monkeys.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a41feaea3a38054f6e07b27979a77bd6
https://doi.org/10.1023/a:1007657109012
https://doi.org/10.1023/a:1007657109012
Autor:
Mark B. Judkins, Stanley C. Gill, Long-Shiuh Chen, Chris Tucker, Daniel W. Drolet, James A. Farmer
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 732:203-212
Aptamers are oligonucleotide ligands selected, in vitro, to bind a specified target protein. The first aptamer to reach human clinical testing is NX1838, a polyethylene glycol conjugated aptamer that inhibits vascular endothelial growth factor. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcd7c27c6305d85c906115d8f32a28f
https://doi.org/10.1016/s0378-4347(99)00285-6
https://doi.org/10.1016/s0378-4347(99)00285-6
Autor:
Ashish Madhukar Vengsarkar, John E. Sipe, Paul Joseph Lemaire, J. B. Judkins, Vikram Bhatia, Turan Erdogan
Publikováno v:
Journal of Lightwave Technology. 14:58-65
Optical fiber communication systems that use optical amplifiers are increasingly seeking high-performance devices that function as spectrally-selective band-rejection filters. For example, ASE filters that improve erbium amplifier performance and ban
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c5fd185407fd623ecadc4bb1158ef0
https://doi.org/10.1109/50.476137
https://doi.org/10.1109/50.476137
Publikováno v:
Canadian Journal of Animal Science. 75:209-218
Twenty-four Polypay lambs (12 sets of twins; 12 ewe and 12 ram lambs) born within a 3-d period were randomly allotted at birth within sex group to be weaned at either 30 (EW) or 60 (LW) d of age. Six lambs (three ewe and three ram lambs)/treatment we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca43d71293de011e97ca120f1058315b
https://doi.org/10.4141/cjas95-031
https://doi.org/10.4141/cjas95-031
Publikováno v:
Ultramicroscopy. 57:251-256
A hybrid finite-difference-time-domain and angular spectrum technique is used to model near-field optical probe fields and the interaction of the fields with a pyrex substrate. Included in this analysis is a study of the effect of various nanometer s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::711c280bbfb2e3033513a8eb50f9e02c
https://doi.org/10.1016/0304-3991(94)00148-g
https://doi.org/10.1016/0304-3991(94)00148-g
Publikováno v:
Radio Science. 28:901-911
In an effort to meet an ever increasing demand for more accurate and realistic integrated photonics simulations, we have developed a multidimensional, nonlinear finite difference time domain (NL-FDTD) Maxwell's equations solver. The NL-FDTD approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffac27759c9dbea60b10f503b3008bde
https://doi.org/10.1029/93rs01100
https://doi.org/10.1029/93rs01100
Publikováno v:
Journal of Animal Science. 71:1320-1325
Alfalfa was labeled in the field with 99 atom % 13CO2 and cut either the same day (C1) or 30 d after labeling (C30). The C1 alfalfa contained 84% of the 13C label in cell contents, whereas C30 alfalfa contained 47% of the 13C label in cell contents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d16205f7fdc2ecc75a63a9c9f15595b2
https://doi.org/10.2527/1993.7151320x
https://doi.org/10.2527/1993.7151320x
Publikováno v:
Animal Feed Science and Technology. 37:323-331
Masticate was collected by ruminal evacuation of four steers grazing intermediate wheatgrass (Thinopyrum intermedium Host) pasture during dormant and active plant growth periods. Masticate was either lyophilized, or oven dried (60 °C) after the mate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::857b74e01ded0d9219a7c51155c7c963
https://doi.org/10.1016/0377-8401(92)90015-x
https://doi.org/10.1016/0377-8401(92)90015-x