Zobrazeno 1 - 10
of 21
pro vyhledávání: '"B. JoNell Hamilton"'
Autor:
B. JoNell Hamilton, Jonathan D. Jones, Sladjana Skopelja-Gardner, Alexey V. Danilov, William F. C. Rigby
Publikováno v:
The Journal of Immunology. 199:1275-1282
Rituximab (RTX) has been the hallmark anti-CD20 mAb for the treatment of B cell neoplasms, including B cell chronic lymphocytic leukemia (B-CLL). Recently, a novel humanized anti-CD20 mAb obinutuzumab (GA101) has been implemented as first-line CLL th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e130488ac5f2e9c1e8ccee77d881c402
https://doi.org/10.4049/jimmunol.1602105
https://doi.org/10.4049/jimmunol.1602105
Publikováno v:
Arthritis & Rheumatology. 69:1381-1386
Objective: Anti-carbamylated protein antibodies (ACarPA) are associated with rheumatoid arthritis (RA) risk and severity and are primarily directed against fibrinogen. The lack of understanding of ACarPA reactivity has limited analysis of their immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e2eec97174353af93066c1d2ec4b77f
https://doi.org/10.1002/art.40098
https://doi.org/10.1002/art.40098
Publikováno v:
Journal of Cellular and Molecular Medicine
Endothelial diaphragms are subcellular structures critical for mammalian survival with poorly understood biogenesis. Plasmalemma vesicle associated protein (PLVAP) is the only known diaphragm component and is necessary for diaphragm formation. Very l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efc073c4f224105a307ed3fee3124a9
https://pubmed.ncbi.nlm.nih.gov/30394679
https://pubmed.ncbi.nlm.nih.gov/30394679
Publikováno v:
Arthritis & Rheumatology. 66:2938-2946
Rituximab (RTX) is a chimeric monoclonal antibody specific for human CD20. The utility of CD20 targeting by RTX has revolutionized the treatment of B cell malignancies (1-3). In addition, RTX has found wide application in many autoimmune disorders, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ce8aaa2f74a93a78e1a015c3608801
https://doi.org/10.1002/art.38798
https://doi.org/10.1002/art.38798
Autor:
B. JoNell Hamilton, Mei-Ling Yang, William F. C. Rigby, Alex H. Gifford, Alix Ashare, Mark J. Mamula, Sladjana Skopelja, Jonathan D. Jones
Publikováno v:
JCI insight. 1(17)
While respiratory failure in cystic fibrosis (CF) frequently associates with chronic infection by Pseudomonas aeruginosa, no single factor predicts the extent of lung damage in CF. To elucidate other causes, we studied the autoantibody profile in CF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036e8bc83aae6a9ba40c05f051ea629e
https://pubmed.ncbi.nlm.nih.gov/27777975
https://pubmed.ncbi.nlm.nih.gov/27777975
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 69(7)
Anti-carbamylated protein (anti-CarP) antibodies are associated with the risk and severity of rheumatoid arthritis (RA) and are primarily directed against fibrinogen. The lack of understanding of anti-CarP antibody reactivity has limited analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8208daed848ffa130f07898700e1c395
https://pubmed.ncbi.nlm.nih.gov/28296337
https://pubmed.ncbi.nlm.nih.gov/28296337
Publikováno v:
Arthritis & Rheumatism. 64:3111-3118
Objective To evaluate loss of the B cell–specific marker CD19 after the addition of rituximab (RTX) to healthy donor blood and to determine the role of complement-mediated cytotoxicity in these cells. Methods Whole blood and peripheral blood mononu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73c2c2d6085b6b29f954d01f6c5891b
https://doi.org/10.1002/art.34560
https://doi.org/10.1002/art.34560
Autor:
B. JoNell Hamilton, John Botson, Ralph C. Nichols, Xiao Wei Wang, William F. C. Rigby, Jane E. Collins, Victoria Uribe, Seth A. Brooks, Moe Zan
Publikováno v:
Molecular Biotechnology. 48:210-217
The study of post-transcriptional regulation is constrained by the technical limitations associated with both transient and stable transfection of chimeric reporter plasmids examining the activity of 3′-UTR cis-acting elements. We report the adapta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cdb72b6113d2c115185e8654cf67b6
https://doi.org/10.1007/s12033-010-9360-8
https://doi.org/10.1007/s12033-010-9360-8
Autor:
William F. C. Rigby, Benjamin M. Terry, Brian L. Henry, Xiao Wei Wang, Moe Zan, Jane E. Collins, Daniel Bloch, B. JoNell Hamilton, Alan Bergeron, Andrew J. Mouland
Publikováno v:
Journal of Biological Chemistry. 283:25606-25616
We report a role for CA repeats in the 3′-untranslated region (3′-UTR) in regulating CD154 expression. Human CD154 is encoded by an unstable mRNA; this instability is conferred in cis by a portion of its 3′-UTR that includes a polypyrimidine-ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c06374e4a9db838b311949ad2adfbfc9
https://doi.org/10.1074/jbc.m802492200
https://doi.org/10.1074/jbc.m802492200
Autor:
Adam J. Pelzek, Jonathan D. Jones, Artur J. de Brum-Fernandes, B. JoNell Hamilton, Gregg J. Silverman, Gilles Boire, Gregory J Challener, William F. C. Rigby, Ariel Masetto, Nathalie Carrier, Henri A. Ménard
Publikováno v:
The Journal of rheumatology. 43(2)
Objective.The presence of anticitrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA) indicates a breach in immune tolerance. Recent studies indicate that this breach extends to homocitrullination of lysines with the formation of anti-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d3f2977e58a8c86068904803a0d63b
https://pubmed.ncbi.nlm.nih.gov/26669911
https://pubmed.ncbi.nlm.nih.gov/26669911