Zobrazeno 1 - 10
of 21
pro vyhledávání: '"B. J. M. Braakhuis"'
Publikováno v:
Laryngo-Rhino-Otologie. 74:742-747
BACKGROUND Cigarette smoking is a well established risk factor for head and neck squamous cell carcinoma. However, data on smoking history are not sufficient to predict which patients are at high risk for the development of multiple primary tumors. I
Publikováno v:
Clinical Otolaryngology. 20:479-482
In head and neck squamous cell carcinoma a reliable serum marker of carcinogenesis should be of predictive value for the development of recurrent disease or a second primary tumour. At the moment, such a tumour marker is not available. Recently, elev
Autor:
H.M. Pinedo, C.L. van der Wilt, J.A.M. van Laar, B. J. M. Braakhuis, G.J. Peters, Fabrizio Franchi, P. Noordhuis, Giovanni Codacci-Pisanelli
Publikováno v:
European Journal of Cancer. 31:1517-1525
Continuous infusions of 5-fluorouracil (5-FU) are increasingly used in the treatment of cancer. Their optimal use, however, has still to be determined since the availability of suitable animal models is limited. We studied continuous infusions in mic
Autor:
Godefridus J. Peters, M. de Jong, C.L. van der Wilt, B. J. M. Braakhuis, H.M. Pinedo, Kees Smid
Publikováno v:
International Journal of Cancer. 61:672-678
Potentiation of the anti-tumor activity of 5-fluorouracil (5FU) by methotrexate (MTX) and leucovorin (LV) requires careful scheduling to achieve the most favorable interactions between these 3 drugs. In vitro the triple combination of MTX/5FU/LV was
Autor:
B. J. M. Braakhuis, M. Gerretsen, Ad H. G. J. Schrijvers, C. J. L. M. Meijer, M. van Walsum, G. B. Snow, G.A.M.S. (Guus) van Dongen, Jasper J. Quak
Publikováno v:
Gerretsen, M, Schrijvers, A H G J, Van Walsum, M, Braakhuis, B J M, Quak, J J, Meijer, C, Snow, G B & Van Dongen, G A M S 1992, ' Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with 131 i-labelled monoclonal antibody e48 igg ', British Journal of Cancer, vol. 66, no. 3, pp. 496-502 . https://doi.org/10.1038/bjc.1992.302
British Journal of Cancer
British Journal of Cancer, 66(3), 496-502. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer, 66(3), 496-502. Nature Publishing Group
Monoclonal antibody (MAb) E48 reacts with a 22 kD antigen exclusively expressed in squamous and transitional epithelia and their neoplastic counterparts. Radiolabelled with99mTc, MAb E48 is capable of targeting metastatic and recurrent disease in pat
Autor:
B. J. M. Braakhuis, M. van Walsum, G. B. Snow, G.A.M.S. (Guus) van Dongen, Ad H. G. J. Schrijvers, M. Gerretsen, Jasper J. Quak
Publikováno v:
Cancer Immunology Immunotherapy, 34(4), 252-258. Springer Science and Business Media Deutschland GmbH
Schrijvers, A H G J, Gerretsen, M, van Walsum, M, Braakhuis, B J M, Quak, J J, Snow, G B & van Dongen, G A M S 1992, ' Potential for targeting head and neck squamous cell carcinoma with monoclonal antibody K984 ', Cancer Immunology Immunotherapy, vol. 34, no. 4, pp. 252-258 . https://doi.org/10.1007/BF01741793
Schrijvers, A H G J, Gerretsen, M, van Walsum, M, Braakhuis, B J M, Quak, J J, Snow, G B & van Dongen, G A M S 1992, ' Potential for targeting head and neck squamous cell carcinoma with monoclonal antibody K984 ', Cancer Immunology Immunotherapy, vol. 34, no. 4, pp. 252-258 . https://doi.org/10.1007/BF01741793
In previous reports we have described the development of mAb K984, reactive with an epitope expressed on the outer cell surface of undifferentiated, proliferating cells in normal stratified squamous epithelia and their neoplastic counterparts [28, 30
Autor:
G. Pratesi, Simon P. Langdon, Oystein Fodstad, H.R. Hendriks, E. Boven, Dietmar P. Berger, B. J. M. Braakhuis, Heinz H. Fiebig
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 5(5)
Summary Background The EORTC New Drug Development Office has initiated a multicenter collaborative program to evaluate the use of human tumor xenografts to predict phase II clinical activity. A first study confirmed the efficacy of doxorubicin and in
Autor:
P. Noordhuis, G.J. Peters, B. J. M. Braakhuis, Gerard W. M. Visser, R. Wedzinga, C. L. Van Der Wilt, K. Smid
Publikováno v:
British Journal of Cancer
A class of new 5-fluorouracil (FU) analogues, the 5-fluoro-5,6-dihydro-6- alkoxy-uracils was synthesised with a modification at the 6-position of the pyrimidine ring. At this position the analogues have a hydroxy or alkoxy group of different chain le