Zobrazeno 1 - 10 of 20 pro vyhledávání: '"B. J. Blaauboer"'
1
Effects of the peroxisome proliferator mono(2-ethylhexyl)phthalate in primary hepatocyte cultures derived from rat, guinea pig, rabbit and monkey. Relationship between interspecies differences in biotransformation and peroxisome proliferating potencies
Autor: H A, Dirven, P H, van den Broek, M C, Peeters, J G, Peters, W C, Mennes, B J, Blaauboer, J, Noordhoek, F J, Jongeneelen
Publikováno v: Biochemical pharmacology. 45(12)
Primary hepatocyte cultures derived from rat, rabbit, guinea pig and monkey have been treated in vitro with metabolites of di(2-ethylhexyl)phthalate, i.e. mono(2-ethylhexyl)phthalate (MEHP), mono(5-carboxy-2-ethylpentyl)phthalate (metabolite V) and m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2aa782384b97336a2b2c8051f9b23c45
https://pubmed.ncbi.nlm.nih.gov/8328980
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2
Hepatic cytochrome P450 induction in goats. Effects of model inducers on the metabolism of alkoxyresorufins, testosterone and ethylmorphine, and on apoprotein and mRNA levels
Autor: G A, van't Klooster, G J, Horbach, M, Natsuhori, B J, Blaauboer, J, Noordhoek, A S, van Miert
Publikováno v: Biochemical pharmacology. 45(1)
Male and female African dwarf goats were treated orally with phenobarbital (PB) or triacetyloleandomycin (TAO), or subcutaneously with beta-naphthoflavone (BNF). Hepatic microsomal cytochrome P450 content was increased by PB and TAO, but not by BNF.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f198b303b3678fe156f754ae1f42e192
https://pubmed.ncbi.nlm.nih.gov/8424805
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3
Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures. The effects of model inducers on apoproteins and biotransformation activities
Autor: H M, Wortelboer, C A, de Kruif, A A, van Iersel, H E, Falke, J, Noordhoek, B J, Blaauboer
Publikováno v: Biochemical pharmacology. 42(2)
The metabolic profile of seven subfamilies of cytochrome P450 (P450IA, IIA, IIB, IIC, IIE, IIIA, IVA) was studied in rat liver (in vivo) and in primary hepatocyte cultures (in vitro) after treatment with various inducers. The dealkylation of 7-ethoxy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::548bcee63d51f5c22667e1bafff05048
https://pubmed.ncbi.nlm.nih.gov/1859452
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7
Abstracts of papers toxicological meeting
Autor: A. C. Beynen, G. W. Meijer, H. F. P. Joosten, A. A. van Kolfschoten, H. B. W. M. Koëter, P. C. Leegwater, J. L. M. Hermens, A. G. Rauws, C. E. Lumley, S. R. Walker, C. W. M. Bodar, P. A. Voogt, H. Wijnne, A. v. d. Zee, D. I. Zandee, P. J. Boogaard, G. J. Mulder, J. F. Nagelkerke, J. H. Boot, C. W. M. van Holsteijn, B. J. Blaauboer, R. P. Bos, J. L. G. Theuws, F. J. Jongeneelen, E. J. Brouwer, F. A. de Wolff, Ruud W. Busker, J. N. M. Commandeur, N. P. E. Vermeulen, R. Coosen, E. Schenk, F. X. R. van Leeuwen, J. G. Vos, J. H. J. Copius Peereboom-Stegeman, H. van Veen, J. Pertijs, L. H. J. C. Danse, K. de Jong, G. J. A. Speijers, J. F. M. de Kom, P. M. Edelbroek, E. G. de Jong, R. A. A. Maes, H. de Vries, G. M. J. Beyersbergen van Henegouwen, M. H. J. Berkhuysen, P. Kalloe, A. de Zwaan, W. Chr de Kock, P. J. den Besten, P. Dogterom, J. A. M. A. Dormans, A. J. F. Boere, L. van Bree, P. J. A. Rombout, C. T. A. Evelo, P. H. S. Fijneman, P. Th. Henderson, A. R. Goeptar, G. R. M. M. Haenen, A. Bast, J. N. L. Tai Tin Tsoi, H. Timmerman, G. Hageman, R. Hermans, J. Kleinjans, M. A. Herweijer, T. C. Bootsman, S. G. van der Meer, R. J. Planta, Frederike I. Kappers, Jacqueline A. A. M. Wondergem-van Eijk, P. P. Kelder, N. J. de Mol, L. H. M. Janssen, E. D. Kroese, M. L. M van de Poll, J. H. N. Meerman, R. A. C. Lock, P. M. Verbost, G. Flik, S. E. Wendelaar Bonga, K. J. Lusthof, W. C. Hennes, R. den Hartogh, I. Kietjens, J. Dornans, P. Rombout, S. A. Schoonderwoerd, J. J. Luijendijk, G. M. J. Beijersbergen van Henegouwen, J. M. te Koppele, B. Coles, B. Ketterer, M. F. van Ginkel, G. B. van der Voet, F. N. A. M. van Pelt, Y. J. M. olde Meierink, P. J. J. H Weterings, C. H. van Os, H. Verhagen, B. Schutte, M. M. J. Reynders, G. H. Blijham, F. ten Hoor, J. C. S. Kleinjans, A. M. Wetzer, H. Weetink, E. C Rietveld, F. Seutter-Berlage, Gerard M. J. Beijersbergen van Henegouwen
Publikováno v: Pharmaceutisch Weekblad. 9:346-356
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0a9812463e55aaf7e904e3daf16a970
https://doi.org/10.1007/bf01956518
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8
Effects of phenylhydroxylamine and aminophenols in Japanese quailin vivo
Autor: C.W.M. van Holsteijn, B. J. Blaauboer, J. G. Wit
Publikováno v: Xenobiotica. 10:495-498
1. The effects of phenylhydroxylamine, and o- and p-aminophenol were studied in the Japanese quail. 2. Symptoms normally observed in aniline-treated birds were seen in quail after phenylhydroxylamine dosage at10 mg/kg. Aminophenols (up to 50 mg/kg) d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb7b7884f86703f165c8e2dc9265636
https://doi.org/10.3109/00498258009033784
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9
Reversed phase high-performance liquid chromatography of heterocyclic aromaticN-oxides: application to measurement ofN-oxidation by microsomes and rat hepatocytes in primary culture
Autor: B. J. Blaauboer, A. J. Paine
Publikováno v: Xenobiotica. 10:655-660
1. The rates of N-oxide formation from pyridine, nicotinamide and isonicotinamide by rat liver microsomes and by cultured rat hepatocytes have been quantified using a simple h.p.l.c. system. 2. Hepatocytes produce hetero-aromatic N-oxides for at leas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8e5fe08fa8ccf6e42ab9165640ccfa
https://doi.org/10.3109/00498258009033799
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10
Abstract of papers
Autor: A. W. T. Konings, H. Joenje, A. Bast, R. Julicher, A. A. J. Van Iersel, B. J. Blaauboer, H. W. Balfoort, P. J. A. Ronbout, P. J. A. Borm, J. J. M. Engelen, E. F. M. Wouters, C. M. H. Swaen, Tj. de Boorder, R. P. Bos, W. J. C. Prinsen, F. J. Jongeneelen, J. L. G. Theuws, P. Th. Henderson, A. Cervantes, G. J. Schuurhuis, H. M. Pinedo, J. Lankelma, J. N. M. Commandeur, R. A. J. Oostendorp, P. R. Schoofs, B. Xu, N. P. E. Vermeulen, R. Coosen, F. X. R. van Leeuwen, J. G. Vos, J. H. H. Thijssen, J. G. Loeber, N. J. de Mol, A. B. C. Becht, J. Koenen, G. Lodder, F. A. de Wolff, M. F. van Ginkel, G. B. van der Voet, P. Dogterom, J. F. Nagelkerke, G. J. Mulder, P. M. Edelbroek, F. G. Zitman, C. T. A. Evelo, H. J. J. M. Niessen, H. M. J. Roelofs, H. E. Falke, A. P. De Groot, M. I. Willems, M. A. M. Franken, R. Kapteijn, E. I. Krajnc, G. R. M. M. Haenen, J. P. M. Plug, H. Timmerman, G. J. Hageman, H. Verhagen, J. C. S. Kleinjans, M. A. Herweijer, T. C. Bootsman, B. J. Scholte, R. J. Planta, E. D. Kroese, R. B. Tijdens, J. H. N. Meerman, K. J. Lusthof, J. G. A. Decuyper, I. L. Groothuis-Pielage, I. M. C. M. Rietjens, R. M. E. Vos, G. M. Alink, P. J. van Bladeren, E. C. Rietveld, H. H. T. M. Ketels, A. M. A. C. Wetzer, F. Seutter-Berlage, P. Rombout, J. Dormans, L. van Bree, M. Marra, H. P. Til, R. A. Woutersen, V. J. Feron, J. J. Clary, A. E. Brandsma, F. A. de Wofff, R. van de Straat, J. de Vries, A. J. F. Boere, P. J. A. Rombout, I. Rietjens, G. Alink, Yvette H. M. van Erp, Petra R. C. M. Heirbaut, Marion J. E. Koopmans, Peter J. J. M. Weterings, H. van Loveren, A. de Klerk, B. Hakkert, H. Vertagen, H. H. W. Thijssen, P. W. Wester, J. H. Canton
Publikováno v: Pharmaceutisch Weekblad. 9:36-45
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::128abd1c27ad609e15cce8b0b7a4f2a1
https://doi.org/10.1007/bf01956491
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