Zobrazeno 1 - 9
of 9
pro vyhledávání: '"B. I. Iaparov"'
Publikováno v:
JETP Lett.
JETP Letters
JETP Letters
Six thermo-activated transient receptor potential (TRP) channels are the molecular basis of the thermosensation for mammals. But the molecular source of their gating remains unknown. In the Letter, we suggest a physically based model for the TRP chan
Publikováno v:
The Journal of General Physiology
Iaparov et al. use in silico modeling to test the effect of changes in the geometric arrangement of RYR channels on calcium release in cardiac myocytes. Their simulations predict a coupling between RYR distribution at the calcium release site and dya
Autor:
B. I. Iaparov, S. Yu. Khamzin
Publikováno v:
Mathematical Analysis With Applications ISBN: 9783030421755
Many essential physiological processes are controlled by calcium. Ca\(^{2+}\) sparks are the elementary events of calcium release from the sarcoplasmic reticulum (SR) via groups of ryanodine receptors (RyRs). Studying Ca\(^{2+}\) sparks is of great i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a4a547d8717005a84d438cbfe27f44d
https://doi.org/10.1007/978-3-030-42176-2_30
https://doi.org/10.1007/978-3-030-42176-2_30
Publikováno v:
European biophysics journal : EBJ. 48(6)
Calcium release sites (CRSs) play a key role in excitation–contraction coupling of cardiac myocytes. Recent studies based on electron tomography and super-resolution imaging revealed that CRSs are not completely filled with ryanodine receptors (RyR
Publikováno v:
Biophysics. 61:614-621
The temperature effect on cardiac ryanodine receptor (RyR) function has been studied within the electron-conformational (EC) model. It’s shown that a simple EC model with an Arrhenius-like temperature dependence of the “internal” and “externa
Publikováno v:
JETP Letters. 102:62-68
Temperature influences many aspects of cardiac excitation-contraction coupling, in particular, hypothermia increases the open probability (Popen) of cardiac sarcoplasmic reticulum (SR) Ca2+-release channels (ryanodine-sensitive RyR channels) rising t
Publikováno v:
Procedia Computer Science
Calcium dynamics plays key role in many intracellular processes. Studying of calcium sparks, that is events of calcium release via groups of ryanodine receptors, or RyR channels, is of a great importance for live sciences. Recent experimental studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d3a91fa3601fc8cccbe26ddf8333e6
https://hdl.handle.net/10995/75639
https://hdl.handle.net/10995/75639
Publikováno v:
Journal Of Physics Conference Series
Publikováno v:
Biophysical Journal. 110(3):262a-263a
Temperature influences many aspects of the cardiac excitation-contraction coupling, in particular, hypothermia increases the open probability (Popen) of cardiac sarcoplasmic reticulum (SR) Ca2+-release channels (ryanodine-sensitive RyR channels) risi