Zobrazeno 1 - 10
of 75
pro vyhledávání: '"B. Hukku"'
Autor:
Erin L. Crawford, James C. Willey, Jeffrey P. DeMuth, B. Hukku, S. Girgis, J.A. Mcraven, David A. Weaver, T.K. Hei
Publikováno v:
Carcinogenesis. 21:205-211
Radon exposure is associated with increased risk for bronchogenic carcinoma. Mutagenesis analyses have revealed that radon induces mostly multi-locus chromosome deletions. Based on these findings, it was hypothesized that deletion analysis of multipl
Publikováno v:
International journal of oncology. 7(3)
Syrian hamster embryo (SHE) cells have a reported culture lifespan limited to 30 to 40 population doublings (PDs). In contrast, we have observed continuous growth of two SHE cell lines without the hallmarks of cellular senescence. Two independent pri
Publikováno v:
Cancer research. 61(16)
Research into molecular and genetic mechanisms underlying familial prostate cancer would be greatly advanced by in vitro models of prostate tumor cells representing primary tumors. We have successfully established an immortalized human prostate epith
Autor:
L, Zhang, J W, Taub, M, Williamson, S C, Wong, B, Hukku, J, Pullen, Y, Ravindranath, L H, Matherly
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(9)
Reduced folate carrier (RFC) transcripts in human leukemias were measured by a competitive PCR assay. Total RNAs were reverse transcribed and amplified in the presence of competitive templates for RFC and beta-actin. RFC transcripts were normalized t
Publikováno v:
Methods in cell biology. 57
Research and development involving the use of cell lines require precise knowledge of the purity and species of origin of the cell lines used. This can only be assured by periodic monitoring of cultured cell lines for possible contamination by other
Publikováno v:
Cancer research. 57(4)
We report the malignant transformation of adult human prostate epithelial cells after multiple exposures to the chemical carcinogen N-nitroso-N-methylurea. Such transformants showed morphological alterations and anchorage-independent growth in soft a
Publikováno v:
Cancer research. 52(23)
The sensitivity of the human glucocorticoid receptor (hGR) gene to mutagenesis by the cancer chemotherapeutic drugs adriamycin, bleomycin, and chlorambucil was evaluated using glucocorticoid-sensitive (dexs) subclones of the human leukemic cell line
Publikováno v:
Advances in experimental medicine and biology. 172
The extensive use of cell cultures for diverse research purposes is one of the truly great international growth industries. With the proliferation of cells comes a responsibility for monitoring them for inter- and intraspecies characteristics. We use
Publikováno v:
Methods in enzymology. 58
Publikováno v:
Investigative ophthalmologyvisual science. 30(3)
We have derived a cell line from an epiretinal membrane excised surgically from a premature female infant born at a gestational age of 25 weeks, and who developed stage 5 retinopathy of prematurity. The cell line, which in early passages appeared imm