Monoclonal antibodies and Fc-fusion protein biologic medicines: A multinational cross-sectional investigation of accessibility and affordability in Asia Pacific regions between 2010 and 2020

Autor: Xinning Tong, Xue Li, Nicole L. Pratt, Jodie B. Hillen, Tyman Stanford, Michael Ward, Elizabeth E. Roughead, Edward Chia-Cheng Lai, Ju-Young Shin, Franco W.T. Cheng, Kuan Peng, Chak Sing Lau, Wai Keung Leung, Ian C.K. Wong

Publikováno v: The Lancet Regional Health. Western Pacific, Vol 26, Iss , Pp 100506- (2022)

Summary: Background: Monoclonal antibody (mAb) and Fc-fusion protein (FcP) are highly effective therapeutic biologics. We aimed to analyse consumption and expenditure trends in 14 Asia-Pacific countries/regions (APAC) and three benchmark countries (t

Externí odkaz: https://doaj.org/article/2d2063d856af4a1a8b6a84b18949b0bd

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Impact of Introducing Infliximab Biosimilars on Total Infliximab Consumption and Originator Infliximab Prices in Eight Regions: An Interrupted Time-Series Analysis

Autor: Kuan Peng, Joseph E. Blais, Nicole L. Pratt, Jeff Jianfei Guo, Jodie B. Hillen, Tyman Stanford, Michael Ward, Edward Chia-Cheng Lai, Ju-Young Shin, Xinning Tong, Min Fan, Franco W. T. Cheng, Jing Wu, Winnie W. Y. Yeung, Chak-Sing Lau, Wai Keung Leung, Ian C. K. Wong, Xue Li

Publikováno v: SSRN Electronic Journal.

Refereed/Peer-reviewed Objective: We aimed to assess whether the introduction of the first infliximab biosimilar was associated with changes in overall infliximab consumption (originator and biosimilars) and price changes to the originator infliximab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4ed3dd9a93bb0dc960b4bd1ba3364e
https://doi.org/10.2139/ssrn.4160682

The design, construction, and commissioning of the KATRIN experiment

Autor: Stefan Welte, N. Titov, N. Trost, Suren Chilingaryan, S. Zadoroghny, J. Mostafa, B. Bieringer, L.I. Minter, B. L. Wall, M. Šefčík, M. Zacher, S. Bauer, C. Rodenbeck, A. P. Vizcaya Hernández, M. Fedkevych, M. Held, H. Bouquet, B. Krasch, P. C.-O. Ranitzsch, F. Block, T. Höhn, K. Vogt, A. Beglarian, C. Weinheimer, Thierry Lasserre, F. Eichelhardt, H. Bolz, Igor Tkachev, M. A. Howe, P. Plischke, C. Bettin, D.A. Peterson, P. Renschler, F. M. Fränkle, J. Grimm, Guido Drexlin, F. Edzards, A. Verbeek, B. Ostrick, K. Mehret, C. Köhler, B.A. VanDevender, M. Erhard, A. Felden, U. Naumann, R. Grössle, J. Kleinfeller, M. Hackenjos, M. Böttcher, Holger Neumann, Volker Hannen, L. La Cascio, B. Bender, K. Helbing, M. Meloni, H. Weingardt, P. Oelpmann, A. Osipowicz, R. Rinderspacher, Klaus Blaum, N.M. Boyd, A. Off, Joseph A. Formaggio, Michael Sturm, M. Deffert, A. Kumb, H. Frenzel, S. Horn, S. Dyba, V. Sibille, Andreas Kopmann, P. J. Doe, H. Bechtler, T. Houdy, D. Hinz, F. Heizmann, Lutz Bornschein, M. Prall, M. Klein, W. Gil, K. Gauda, G.A. Cox, A. Kovalík, K. Schlösser, A. I. Berlev, K.J. Wierman, M. Kaiser, S. Schneidewind, U. Besserer, R. Berendes, S. Fischer, A. Schaller, A. Jansen, S. Bobien, K. Altenmüller, Y.-R. Yen, O. Rest, E. L. Martin, K. Urban, A. Menshikov, R. G. H. Robertson, Reiner Vianden, A. Kosmider, M. Ryšavý, S. Groh, Ferenc Glück, Alan Poon, H.-W. Ortjohann, D. Hillesheimer, Alexey Lokhov, J. Reich, W. Seller, T. Brunst, G. P. Zeller, M. Slezák, J. A. Dunmore, S. Niemes, J. Bast, P. Rohr, S. Lichter, M. Korzeczek, M. Aker, M. Babutzka, Florian Priester, Marc Weber, K. Debowski, T. D. Van Wechel, Susanne Mertens, S. Görhardt, M. Descher, B. Hillen, D. Vénos, A. Marsteller, F. Friedel, A. Huber, S. Hickford, M. Machatschek, F. Harms, B. Lehnert, Felix Spanier, M. Mark, P. Schäfer, J. Hartmann, R. Sack, R. Gehring, H. Seitz-Moskaliuk, J.F. Amsbaugh, L. A. Thorne, J. Letnev, Marco Röllig, C. Röttele, E. Ellinger, B. Leiber, Alejandro Saenz, T. James, Beate Bornschein, Sascha Wüstling, M. Zboril, M. Kleesiek, W. Xu, T. S. Caldwell, Werner Rodejohann, Matthias Arenz, Ondřej Lebeda, L. Schlüter, M. Kraus, Joachim Wolf, N. Haußmann, Daniel Siegmann, J. Kellerer, A. Fulst, H. Krause, M. Sun, M. Steidl, O. Kazachenko, Benjamin Monreal, D. Díaz Barrero, E. Malcherek, J. Bohn, M. Leber, O. Dragoun, Denis Tcherniakhovski, T.J. Corona, J. Behrens, G. C. Harper, N. Kunka, M. Sagawe, Magnus Schlösser, Diana Parno, J. Wendel, Steffen Grohmann, S. Holzmann, L. Köllenberger, T.H. Burritt, D. Eversheim, Marcus Beck, Thomas Thümmler, L. Kuckert, R. Hiller, N. Wandkowsky, Z. Chaoui, K. Eitel, D. Hilk, M. Hötzel, Kathrin Valerius, C. Weiss, S. Rupp, M. Kleifges, C. Karl, M. Schrank, L. Schimpf, R. J. Lewis, J. F. Wilkerson, H. Schön, L. Kippenbrock, K. Schönung, R. Gumbsheimer, G. B. Franklin, C. Melzer, Helmut H. Telle, J. Schwarz, W. Q. Choi, J. M. Lopez Poyato, D. Häßler, B. Schulz, Ralph Engel, K. Müller, Sanshiro Enomoto, T. L. Le, K. Bokeloh, A. W. Myers

Publikováno v: Journal of Instrumentation, 16 (08), Art.-Nr.: T08015
JINST
JINST, 2021, 16, pp.T08015. ⟨10.1088/1748-0221/16/08/T08015⟩
Journal of Instrumentation
JINST, 2021, 16 (08), pp.T08015. ⟨10.1088/1748-0221/16/08/T08015⟩

The KArlsruhe TRItium Neutrino (KATRIN) experiment, which aims to make a direct and model-independent determination of the absolute neutrino mass scale, is a complex experiment with many components. More than 15 years ago, we published a technical de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633e0f26a8b7cad02a2a93d5bc8a9772
https://cronfa.swan.ac.uk/Record/cronfa58010/Download/58010__20967__4f42fa0a1c0641a4a1e9fb58590e3f03.pdf

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