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The long‐term effects of non‐steroidal anti‐inflammatory drugs in osteoarthritis of the knee: a randomized placebo‐controlled trial

Autor: J. Wotjulewski, Coppock Js, T. J. Daymond, D. L. Scott, Hedley Berry, L. Fernandes, B. Hazleman, F. Nichol, Ali S M Jawad, Anthony D. Woolf, R W Jubb, M. Webley, P. McGill, J. Palit, David V. Doyle, Hilary A Capell, J. Hunter, E. C. Huskisson, T. Kennedy

Publikováno v: Rheumatology. 39:1095-1101

Background Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat osteoarthritis (OA), though their long-term efficacy is uncertain. We report a comparison of the symptomatic responses to therapy with tiaprofenic acid, indomethacin a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e45586f89b14bc0512959912612f9d4a
https://doi.org/10.1093/rheumatology/39.10.1095

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Laboratory investigations useful in the evaluation of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA)

Autor: B, Hazleman

Publikováno v: Clinical and experimental rheumatology. 18(4 Suppl 20)

The most useful investigation in supporting the clinical diagnosis of PMR/GCA is elevation of the erythrocyte sedimentation rate (ESR) or viscosity. Acute phase proteins, particularly CRP, are also elevated but in most cases are not more helpful than

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::de53835f76bd30980bea814835e7d3ef
https://pubmed.ncbi.nlm.nih.gov/10948756

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Cytidine deaminase may be a useful marker in differentiating elderly onset rheumatoid arthritis from polymyalgia rheumatica/giant cell arteritis

Autor: D, Kassimos, J R, Kirwan, V, Kyle, B, Hazleman, P, Dieppe

Publikováno v: Clinical and experimental rheumatology. 13(5)

PMR/GCA is a relatively common inflammatory disease in the elderly population. Clinical differentiation from a polymyalgic onset of RA in the elderly can be difficult. We have examined in a preliminary study the hypothesis that serum cytidine deamina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1de353eb1d26ba2a773aeefafef00801
https://pubmed.ncbi.nlm.nih.gov/10609079

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A longitudinal study of anticardiolipin antibody in polymyalgia rheumatica and giant cell arteritis

Autor: K, Chakravarty, G, Pountain, P, Merry, M, Byron, B, Hazleman, D G, Scott

Publikováno v: The Journal of rheumatology. 22(9)

To determine the incidence of elevated levels of anticardiolipin antibody (aCL) in patients with newly diagnosed polymyalgia rheumatica (PMR) and/or giant cell arteritis (GCA); and to determine the relationship between these antibodies at diagnosis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41466dbadb08b587fa4a155067bef474
https://pubmed.ncbi.nlm.nih.gov/8523347

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Acemetacin in the long-term therapy of rheumatoid arthritis

Autor: Robert M. Bernstein, B Hazleman

Publikováno v: Current medical research and opinion. 13(2)

An open label study was carried out to assess the long-term use of acemetacin in patients suffering from rheumatoid arthritis. One hundred and two patients were treated with acemetacin, some patients for up to a 12-month period. Analysis of efficacy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9867aa40b4b5927a39b8543cf8275bbf
https://pubmed.ncbi.nlm.nih.gov/8325042

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Prolonged effect of CGRP in Raynaud's patients: a double-blind randomised comparison with prostacyclin

Autor: Claire Dickerson, S. Shawket, B. Hazleman, Morris J. Brown

1. Calcitonin gene related peptide (CGRP) is a potent endogenous vasodilator to which we have previously demonstrated a specific hypersensitivity in skin blood flow in the hands in patients with Raynaud's disease. 2. We have now investigated whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd3627cd5ff9dcd4fd927e0058331e3
https://europepmc.org/articles/PMC1368445/

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