Zobrazeno 1 - 10
of 721
pro vyhledávání: '"B. Haase"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Congenital sensorineural deafness (CSD) has been reported to affect up to 30% of Dalmatian dogs world-wide and while unilaterally deaf dogs can live a close to normal life, dogs suffering bilateral deafness are frequently euthanized. Extreme
Externí odkaz:
https://doaj.org/article/74a6b8601c5c49f9a683aea301be28a3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Flow cytometry is a useful and efficient method for the rapid characterization of a cell population based on the optical and fluorescence properties of individual cells. Ideally, the cell population would consist of only healthy viable cells
Externí odkaz:
https://doaj.org/article/c2f1f5baa9d342979c554d6780ea9360
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/c067da6488814f22a7fe9426e6d8f8a5
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract Background Cell and circadian cycles control a large fraction of cell and organismal physiology by regulating large periodic transcriptional programs that encompass anywhere from 15 to 80% of the genome despite performing distinct functions.
Externí odkaz:
https://doaj.org/article/0f55cfa96ce9411ebaf32eda110b0971
Autor:
Breschine Cummins, Francis C Motta, Robert C Moseley, Anastasia Deckard, Sophia Campione, Marcio Gameiro, Tomáš Gedeon, Konstantin Mischaikow, Steven B Haase
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010145 (2022)
Large programs of dynamic gene expression, like cell cyles and circadian rhythms, are controlled by a relatively small "core" network of transcription factors and post-translational modifiers, working in concerted mutual regulation. Recent work sugge
Externí odkaz:
https://doaj.org/article/55e1e7261831478a89eda5fc425d2f41
Autor:
Joseph W. Saelens, Jens E. V. Petersen, Elizabeth Freedman, Robert C. Moseley, Drissa Konaté, Seidina A. S. Diakité, Karim Traoré, Natalie Vance, Rick M. Fairhurst, Mahamadou Diakité, Steven B. Haase, Steve M. Taylor
Publikováno v:
mSphere, Vol 6, Iss 5 (2021)
Sickle-trait hemoglobin (HbAS) confers nearly complete protection from severe, life-threatening malaria, yet the molecular mechanisms that underlie HbAS protection from severe malaria remain incompletely understood. Here, we used transcriptome sequen
Externí odkaz:
https://doaj.org/article/5f477ea7cd1147b6b6df7e4886dd328f
Publikováno v:
Digital Discovery. 2:12-27
The discoveries that will advance science in profound ways will be made possible by collaborative, multidisciplinary efforts. These efforts require practices and incentives for sharing methods and data, and for leveraging complementary capabilities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64743de1589546737f341b709f5ce3b5
https://doi.org/10.1039/d2dd00061j
https://doi.org/10.1039/d2dd00061j
Autor:
Julien Record, Anton Sendel, Joanna S. Kritikou, Nikolai V. Kuznetsov, Hanna Brauner, Minghui He, Noemi Nagy, Mariana M.S. Oliveira, Elena Griseti, Christoph B. Haase, Jenny Dahlström, Sanjaykumar Boddul, Fredrik Wermeling, Adrian J. Thrasher, Chaohong Liu, John Andersson, Hans-Erik Claesson, Ola Winqvist, Siobhan O. Burns, Magnus Björkholm, Lisa S. Westerberg
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Megakaryoblastic leukemia 1 (MKL1) is a coactivator of serum response factor and together they regulate transcription of actin cytoskeleton genes. MKL1 is associated with hematologic malignancies and immunodeficiency, but its role in B cells is unexp
Externí odkaz:
https://doaj.org/article/d0de30ab92fb41d9b2253b0c0a309db4
Publikováno v:
Nature Communications. 14
A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26c2396b2b1d31ba63e865aa10fc716
https://doi.org/10.1038/s41467-023-37897-9
https://doi.org/10.1038/s41467-023-37897-9
Autor:
Max A. B. Haase, Luciana Lazar-Stefanita, Guðjón Ólafsson, Aleksandra Wudzinska, Michael J. Shen, David M. Truong, Jef D. Boeke
Publikováno v:
bioRxiv
SummaryIn addition to replicative histones, eukaryotic genomes encode a repertoire of non-replicative variant histones providing additional layers of structural and epigenetic regulation. Here, we systematically replaced individual replicative human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddc0537fedd44cea037bcc21faba497
https://europepmc.org/articles/PMC10187286/
https://europepmc.org/articles/PMC10187286/
