Výsledky vyhledávání - "B. H. PETERSEN"

Inhibition of ex vivo neutrophil activation by oral LY293111, a novel leukotriene B4 receptor antagonist

Autor: B. J. Cerimele, R. A. Lucas, S. M. Spaethe, P. Marder, L. L. Froelich, B. H. Petersen, T. Tanner

Publikováno v: British Journal of Clinical Pharmacology. 42:457-464

1. The effects of orally administered LY293111 on ex vivo neutrophil Mac-1 upregulation were determined in a total of 24 healthy male subjects within three study periods. 2. In the first period, eight volunteers received 60 mg LY293111 or placebo thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e7ba999b7b587a30b822dec3337332
https://doi.org/10.1046/j.1365-2125.1996.43210.x

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Detection of human growth hormone receptors on IM-9 cells and peripheral blood mononuclear cell subsets by flow cytometry: correlation with growth hormone-binding protein levels

Autor: Kathryn A. Skuza, A Chartoff, Robert Rapaport, Irene N. Sills, B. H. Petersen, J. Labus, L Green, P. Barrett, M Stene, L Goode

Publikováno v: The Journal of clinical endocrinology and metabolism. 80(9)

We have developed a method using flow cytometry to identify fluorescein-conjugated GH receptors (GHR) on IM-9 lymphocytes and circulating peripheral blood mononuclear cell subsets. Binding to IM-9 cells and peripheral blood mononuclear cells was conc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7622415304f9bd542de38c6714ac66e
https://pubmed.ncbi.nlm.nih.gov/7673403

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Quantitation of human anti-mouse antibody in serum by flow cytometry

Autor: B. H. Petersen, J. M. Labus

Publikováno v: Cytometry. 13(3)

Clinical investigations utilizing murine monoclonal antibodies require techniques for the detection of the human anti-mouse antibody (HAMA) response in patient serum. We report here a flow cytometric assay for the quantitation of HAMA. Commercially a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ce96d522f0dfe9de7942b2bb12265d
https://pubmed.ncbi.nlm.nih.gov/1576893

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The human immune response to KS1/4-desacetylvinblastine (LY256787) and KS1/4-desacetylvinblastine hydrazide (LY203728) in single and multiple dose clinical studies

Autor: B H, Petersen, S V, DeHerdt, D W, Schneck, T F, Bumol

Publikováno v: Cancer research. 51(9)

Monoclonal antibody (MoAb) conjugates have been used to treat a variety of malignancies. The majority of the MoAbs which have been used therapeutically are from murine sources. The infusion of these foreign proteins into humans can be expected to eli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db9e9c79150a007598395c231c48edbe
https://pubmed.ncbi.nlm.nih.gov/2015593

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Two distinct abnormalities in patients with C8 alpha-gamma deficiency. Low level of C8 beta chain and presence of dysfunctional C8 alpha-gamma subunit

Autor: Francesco Tedesco, J M Sodetz, L Roncelli, V Agnello, B H Petersen

Publikováno v: The Journal of clinical investigation. 86(3)

The sera from three C8 alpha-gamma deficient patients previously reported to have a selective C8 alpha-gamma defect were analyzed by SDS-PAGE and Western blot using two polyclonal antisera to C8 alpha-gamma and a monoclonal antibody to C8 alpha. All

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4e564e27da62470e1ab7bad3bea557
https://pubmed.ncbi.nlm.nih.gov/2394837

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Complement consumption gonococcal peptidoglycan

Autor: B H Petersen, R S Rosenthal

Publikováno v: Infection and Immunity. 35:442-448

Purified peptidoglycan (PG) obtained from Neisseria gonorrhoeae was tested for the ability to consume complement in normal human sera. Sonicated PG (S-PG), a heterogeneous mixture of soluble fragments (molecular weight, greater than 10(6)), as well a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805143a1227be707fd9417dd2666ac25
https://doi.org/10.1128/iai.35.2.442-448.1982

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Human deficiency of the eighth component of complement. The requirement of C8 for serum Neisseria gonorrhoeae bactericidal activity

Autor: G F Brooks, B H Petersen, J A Graham

Publikováno v: Journal of Clinical Investigation. 57:283-290

The serum of a 23-yr-old woman with prolonged disseminated gonococcal infection syndrome failed to normally promote hemolysis of sensitized sheep red blood cells (RBC). The patient's serum was deficient in the eight component of complement (C8) as de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84a375c94614b04c2371260afa58d92
https://doi.org/10.1172/jci108279

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Human seminal plasma inhibition of antibody complement-mediated killing and opsonization of Neisseria gonorrhoeae and other gram-negative organisms

Autor: G F Brooks, D P Stites, C J Lammel, B H Petersen

Publikováno v: Journal of Clinical Investigation. 67:1523-1531

Seminal plasma diluted 1:5-1:1,000 gave marked inhibition of serum antibody complement-mediated bactericidal and opsonic effects against Neisseria gonorrhoeae and other gram-negative organisms. Serum that was bactericidal at a dilution of 1:5,120 was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4635e77e686b33aee2757814d0bfac1e
https://doi.org/10.1172/jci110183

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