Zobrazeno 1 - 10
of 33
pro vyhledávání: '"B. H. Lubin"'
Publikováno v:
Blood. 95(4)
Phospholipid asymmetry is well maintained in erythrocyte (RBC) membranes with phosphatidylserine (PS) exclusively present in the inner leaflet. The appearance of PS on the surface of the cell can have major physiologic consequences, including increas
Publikováno v:
Advances in pediatrics. 46
Publikováno v:
The Biochemical journal.
Full-length cDNA species encoding two forms of acyl-CoA synthetase from a K-562 human erythroleukaemic cell line were cloned, sequenced and expressed. The first form, named long-chain acyl-CoA synthetase 5 (LACS5), was found to be a novel, unreported
Publikováno v:
Blood. 87(6)
Acute chest syndrome (ACS) is associated with significant morbidity and is the leading cause of death in patients with sickle cell disease (SCD). Recent reports suggest that bone marrow fat embolism can be detected in many cases of severe ACS. Secret
Autor:
A T, Matsunaga, B H, Lubin
Publikováno v:
Clinics in perinatology. 22(3)
Evaluation of hemolytic anemia in the newborn may be complicated owing to the physiologic changes that occur during this time; however, the newborn period is a time when congenital red cell abnormalities may first present and when maternal factors ne
Publikováno v:
Blood. 81(4)
In the human erythrocyte membrane phosphatidylcholine and sphingomyelin reside mainly in the outer leaflet, whereas the aminophospholipids, phosphatidylethanolamine and phosphatidylserine, are mainly found in the inner leaflet. Maintenance of phospho
Publikováno v:
The Journal of laboratory and clinical medicine. 118(1)
To investigate the relative importance of catalase and glutathione in erythrocyte oxidant defense, human and mouse (normal and acatalasemic) erythrocytes were reversibly lysed and resealed in the presence of exogenous catalase or glutathione. This re
Publikováno v:
The Journal of biological chemistry. 265(29)
Altered membrane proteins have been previously described in beta thalassemia and are thought to play an important role in the shortened erythrocyte survival. To investigate the mechanism by which these changes occur, purified heme-containing alpha-he
Publikováno v:
The Journal of laboratory and clinical medicine. 115(4)
We have recently modified the dialysis tubing osmotic lysis and resealing method to examine the role of intracellular red blood cell (RBC) antioxidants. However, the potential effect of resealing on the RBC was not fully investigated. This study exam
Autor:
M. Grossi, Bruce R. Blazar, John E. Wagner, Elliott Vichinsky, S. L. Abel, B. H. Lubin, L. Krishnamurti
Publikováno v:
Journal of Pediatric Hematology/Oncology. 22:387