Zobrazeno 1 - 10
of 88
pro vyhledávání: '"B. Grigsby"'
Autor:
Kolter B. Grigsby, Regina A. Mangieri, Amanda J. Roberts, Marcelo F. Lopez, Evan J. Firsick, Kayla G. Townsley, Alan Beneze, Jessica Bess, Toby K. Eisenstein, Joseph J. Meissler, John M. Light, Jenny Miller, Susan Quello, Farhad Shadan, Michael Skinner, Heather C. Aziz, Pamela Metten, Richard A. Morrisett, John C. Crabbe, Marisa Roberto, Howard C. Becker, Barbara J. Mason, Angela R. Ozburn
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Treatment options for alcohol use disorders (AUDs) have minimally advanced since 2004, while the annual deaths and economic toll have increased alarmingly. Phosphodiesterase type 4 (PDE4) is associated with alcohol and nicotine dependence. PDE4 inhib
Externí odkaz:
https://doaj.org/article/53c157cfc03541cb8b6a5df7afdc653b
Autor:
Antonia M. Savarese, Kolter B. Grigsby, Bryan E. Jensen, Marissa B. Borrego, Deborah A. Finn, John C. Crabbe, Angela R. Ozburn
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
The High Drinking in the Dark (HDID-1) line of mice has been selectively bred for achieving high blood alcohol levels (BALs) in the Drinking in the Dark task, a model of binge-like drinking. Recently, we determined that glucocorticoid receptor (GR) a
Externí odkaz:
https://doaj.org/article/ea0303363705443ca5f48492ee739b51
Autor:
Kolter B. Grigsby, Nathan R. Kerr, Taylor J. Kelty, Xuansong Mao, Thomas E. Childs, Frank W. Booth
Publikováno v:
Journal of Functional Morphology and Kinesiology, Vol 8, Iss 1, p 6 (2022)
Physical activity (PA) is a non-invasive, cost-effective means of reducing chronic disease. Most US citizens fail to meet PA guidelines, and individuals experiencing chronic stress are less likely to be physically active. To better understand the bar
Externí odkaz:
https://doaj.org/article/a86384a3fe844f21b62938de2a437f98
Autor:
Kolter B Grigsby, Antonia M Savarese, Pamela Metten, Barbara J Mason, Yuri A Blednov, John C Crabbe, Angela R Ozburn
Publikováno v:
Neuroscience Insights, Vol 15 (2020)
High Drinking in the Dark (HDID-1) mice represent a unique genetic risk model of binge-like drinking and a novel means of screening potential pharmacotherapies to treat alcohol use disorders (AUDs). We tested the effects of tacrolimus (0, 0.5, 1, and
Externí odkaz:
https://doaj.org/article/33843f39e6a143489b0e91f439c8a6d1
Akademický článek
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Autor:
Bryan E. Jensen, Kayla G. Townsley, Kolter B. Grigsby, Pamela Metten, Meher Chand, Miracle Uzoekwe, Alex Tran, Evan Firsick, Katherine LeBlanc, John C. Crabbe, Angela R. Ozburn
Publikováno v:
Brain Sciences, Vol 11, Iss 2, p 189 (2021)
Alcohol use disorder (AUD) is a devastating psychiatric disorder that has significant wide-reaching effects on individuals and society. Selectively bred mouse lines are an effective means of exploring the genetic and neuronal mechanisms underlying AU
Externí odkaz:
https://doaj.org/article/277bd0ad10ee40c9a3f55b6c4536e17b
Autor:
Xuansong Mao, Kolter B. Grigsby, Taylor J. Kelty, Nathan R. Kerr, Thomas E. Childs, Frank W. Booth
Publikováno v:
Neuroscience. 509
Understanding the neuro-molecular mechanisms that mediate the quantity of daily physical activity (PA) level is of medical significance, given the tremendous health benefits associated with greater physical activity. Here, we examined the effects of
Autor:
Antonia M. Savarese, Kolter B. Grigsby, Bryan E. Jensen, Marissa B. Borrego, Deborah A. Finn, John C. Crabbe, Angela R. Ozburn
Publikováno v:
Frontiers in behavioral neuroscience. 16
The High Drinking in the Dark (HDID-1) line of mice has been selectively bred for achieving high blood alcohol levels (BALs) in the Drinking in the Dark task, a model of binge-like drinking. Recently, we determined that glucocorticoid receptor (GR) a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Alex Tran, Kayla G. Townsley, Marissa B. Borrego, Amy Chan, Angela R. Ozburn, Evan J. Firsick, Antonia Savarese, Kolter B. Grigsby
Publikováno v:
Neuropharmacology. 203
The nucleus accumbens (NAc) is important for regulating a number of behaviors, including alcohol and substance use. We previously found that chemogenetically manipulating neuronal activity in the NAc core regulates binge-like drinking in mice. The ce