Zobrazeno 1 - 10
of 52
pro vyhledávání: '"B. Gourdier"'
Publikováno v:
Drug Safety. 29:911-1010
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fd5759179c8804db326d167a8afe074
https://doi.org/10.2165/00002018-200629100-00156
https://doi.org/10.2165/00002018-200629100-00156
Publikováno v:
Anti-Cancer Drugs. 7:213-219
Brain levels of the antineoplastic compound, vinorelbine, and its effects on the permeability of the blood-brain barrier (BBB) were studied. Preliminary experiments were carried out to define the dose of 10 mg/kg and the delay of 3 h after infusion r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2693ebd2fd8ecc5d71b6ab2e85c718
https://doi.org/10.1097/00001813-199602000-00011
https://doi.org/10.1097/00001813-199602000-00011
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 663:390-394
A high-performance liquid chromatographic method was developed for the determination in plasma (400-microliters sample) of a vinca alkaloid, vinorelbine. The analysis was performed by using an octadecylsilane column and heptanesulfonic acid as ion-pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4506f24f06ebaef78de4837f62c2c2ae
https://doi.org/10.1016/0378-4347(94)00451-a
https://doi.org/10.1016/0378-4347(94)00451-a
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 581:93-99
A high-performance liquid chromatographic method has been developed for the determination within tumour cells of a new vinca alkaloid, vinorelbine. Extractions of vinorelbine from cells were carried out using absolute ethanol. The extracts were injec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e43fc94ac4c663f3a4c1eb4895f1dc8
https://doi.org/10.1016/0378-4347(92)80451-u
https://doi.org/10.1016/0378-4347(92)80451-u
Publikováno v:
Pharmaceutical research. 16(8)
Establishment of the pharmacokinetic profile of methotrexate (MTX) in the extracellular fluid (ECF) of a brain C6-glioma in rats.Serial collection of plasma samples and ECF dialysates after i.v. infusion of MTX (50 or 100 mg/kg) for 4 h. HPLC assay.H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b841f23750423506d6cbd92819db2c16
https://pubmed.ncbi.nlm.nih.gov/10468023
https://pubmed.ncbi.nlm.nih.gov/10468023
Publikováno v:
Pharmaceutical research. 15(1)
To determine of the pharmacokinetic profile of methotrexate (MTX) in blood and extracellular fluid (ECF) of VX2 tumor and muscle in rabbits.Microdialysis probes were inserted into VX2 tumor and in muscle tissue. Following intravenous administration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebc2ec36fa8df34919943fa64ac32902
https://pubmed.ncbi.nlm.nih.gov/9487560
https://pubmed.ncbi.nlm.nih.gov/9487560
Publikováno v:
Anticancer research. 15(6B)
The effects of the antineoplastic compound, vinorelbine, on the permeability of the blood-brain barrier (BBB) to the complex Evans blue/albumin were studied. Vinorelbine, at a dose range from 5 to 10 mg/kg, was infused (4 ml/kg over 2 min) into the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49e956d65bae1bba23f08cf4d6abfdee
https://pubmed.ncbi.nlm.nih.gov/8669830
https://pubmed.ncbi.nlm.nih.gov/8669830
Publikováno v:
Bulletin du cancer. 81(10)
A phenotype of resistance to the new vinca alkaloid Navelbine was induced in the J82 human bladder carcinoma cells. The resistance factor of the resistant cell line (J82-NVB) to Navelbine was 17. The resistance phenotype of these cells is not a multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6ed5a4a7861b87189c6ae387f5dde0d
https://pubmed.ncbi.nlm.nih.gov/7734773
https://pubmed.ncbi.nlm.nih.gov/7734773
Publikováno v:
Anti-Cancer Drugs. 7:213
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72174d785ffbcca1939aa01657328041
https://doi.org/10.1097/00001813-199603000-00011
https://doi.org/10.1097/00001813-199603000-00011
Publikováno v:
Tetrahedron Letters. 15:1597-1600
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c92ea3c335d995c7c0cf81565c852189
https://doi.org/10.1016/s0040-4039(01)82529-6
https://doi.org/10.1016/s0040-4039(01)82529-6