Zobrazeno 1 - 10
of 12
pro vyhledávání: '"B. G. van den Hoogen"'
Publikováno v:
Journal of Virology, 96(17):e0072322. American Society for Microbiology
The production of type I interferon (IFN) is the hallmark of the innate immune response. Most, if not all, mammalian viruses have a way to circumvent this response. Fundamental knowledge on viral evasion of innate immune responses may facilitate the
Autor:
J F, de Graaf, S, van Nieuwkoop, D, de Meulder, P, Lexmond, T, Kuiken, D, Groeneveld, R A M, Fouchier, B G, van den Hoogen
Publikováno v:
Veterinary Microbiology, 269:109437. Elsevier
Newcastle Disease virus (NDV) has shown promise as an oncolytic virus for treatment of a wide range of tumours. NDV with a multi-basic cleavage site (MBCS) in the fusion (F) protein (NDV F3aa) has increased oncolytic efficacy in several tumour models
Publikováno v:
Cytokine and Growth Factor Reviews, 56, 124-132. Elsevier
Oncolytic virus immunotherapy is rapidly gaining interest in the field of immunotherapy against cancer. The minimal toxicity upon treatment and the dual activity of direct oncolysis and immune activation make therapy with oncolytic viruses (OVs) an i
Publikováno v:
Cytokine & Growth Factor Reviews, 41, 28-39. Elsevier
Cytokine & Growth Factor Reviews
Cytokine & Growth Factor Reviews
Graphical abstract
Highlights • Oncolytic viruses expressing immune modulators as transgene enhance the efficacy of anti-tumor therapies. • The enhanced efficacy is dependent on the combination of virus and immune modulator. • The localize
Highlights • Oncolytic viruses expressing immune modulators as transgene enhance the efficacy of anti-tumor therapies. • The enhanced efficacy is dependent on the combination of virus and immune modulator. • The localize
Autor:
Johan Neyts, S van Nieuwkoop, Ron A. M. Fouchier, Dirk Jochmans, Saskia L. Smits, B G van den Hoogen
Publikováno v:
Antimicrobial Agents & Chemotherapy, 60(8), 4620-4629. American Society for Microbiology
The clinical impact of infections with respiratory viruses belonging to the family Paramyxoviridae argues for the development of antiviral therapies with broad-spectrum activity. Favipiravir (T-705) has demonstrated potent antiviral activity against
Autor:
S E, Smith, D C, Busse, S, Binter, S, Weston, C, Diaz Soria, B M, Laksono, S, Clare, S, Van Nieuwkoop, B G, Van den Hoogen, M, Clement, M, Marsden, I R, Humphreys, M, Marsh, R L, de Swart, R S, Wash, J S, Tregoning, P, Kellam
Publikováno v:
Journal of Virology
Host susceptibility to viral infection is multifactorial, but early control of viruses not previously encountered is predominantly mediated by the interferon-stimulated gene (ISG) family. There are upwards of 300 of these genes, the majority of which
Autor:
Rutger K. Balvers, Sean E. Lawler, Michał Nowicki, Jenneke Kloezeman, Ennio Antonio Chiocca, B G van den Hoogen, W van den Bossche, Andreas Kremer, Martine L.M. Lamfers, Sieger Leenstra, L. M. E. Berghauser Pont, Clemens M F Dirven, Hiroaki Wakimoto
Publikováno v:
Gene Therapy, 22(12), 947-959. Nature Publishing Group
Oncolytic viruses (OV) have broad potential as an adjuvant for the treatment of solid tumors. The present study addresses the feasibility of clinically applicable drugs to enhance the oncolytic potential of the OV Delta24-RGD in glioblastoma. In tota
Autor:
B G, van den Hoogen, R A M, Fouchier
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1602
Human metapneumovirus (HMPV), a single-stranded negative-sense RNA virus belonging to the family Paramyxoviridae, is associated with respiratory tract illness, primarily in young children and persons with underlying disease. Based on genetic and anti
Autor:
B G van den Hoogen, Ron A. M. Fouchier
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969623
Human metapneumovirus (HMPV), a single-stranded negative-sense RNA virus belonging to the family Paramyxoviridae, is associated with respiratory tract illness, primarily in young children and persons with underlying disease. Based on genetic and anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c4de8f037874a7287c4e29eb62a2032
https://doi.org/10.1007/978-1-4939-6964-7_9
https://doi.org/10.1007/978-1-4939-6964-7_9
Autor:
Hubert G. M. Niesters, B G van den Hoogen, Martin Schutten, M.E. van der Ende, A.D.M.E. Osterhaus, Rob A. Gruters
Publikováno v:
Journal of Virological Methods, 88, 81-87. Elsevier
An assay is described for the quantification of human immunodeficiency virus type 2 (HIV-2) RNA in EDTA plasma based on RT-PCR using the Taqman real-time PCR detection method. As standard, an electron microscopically counted virus stock of HIV-2 stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536005c7d9fb0e1b0b012bef167a9c28
https://pure.eur.nl/en/publications/b1c7b3ae-e945-4b8e-988a-683bcabf1fbb
https://pure.eur.nl/en/publications/b1c7b3ae-e945-4b8e-988a-683bcabf1fbb