Výsledky vyhledávání - "B. G. Mattias Luukkonen"

Kaposi's Sarcoma-Associated Herpesvirus-Induced Upregulation of the c-kitProto-Oncogene, as Identified by Gene Expression Profiling, Is Essential for the Transformation of Endothelial Cells

Autor: Michael Heinrich, Jay A. Nelson, Yolanda C. Bell, Ashlee V. Moses, Michael A. Jarvis, B. G. Mattias Luukkonen, Cecily L. Wait, Brian J. Druker, Klaus Früh, Rebecca Ruhl, Diana J. Griffith, Camilo Raggo

Publikováno v: Journal of Virology. 76:8383-8399

Kaposi's sarcoma (KS), the most frequent malignancy afflicting AIDS patients, is characterized by spindle cell formation and vascularization. Infection with KS-associated herpesvirus (KSHV) is consistently observed in all forms of KS. Spindle cell fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e036a7d85945d8b2c7d3e73ca22926
https://doi.org/10.1128/jvi.76.16.8383-8399.2002

Zobrazit plný text záznamu

Virogenomics: a novel approach to antiviral drug discovery

Autor: Klaus Früh, B. G. Mattias Luukkonen, Yolanda C. Bell, Peter Ghazal, Kenneth Alan Simmen

Publikováno v: Drug Discovery Today. 6:621-627

Target discovery in virology has been limited to the few open-reading frames encoded by viral genomes. However, several recent examples show that inhibiting host-cell proteins can prevent viral infection. The human genome sequence should, therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d7826e6ed241b047e5bd2f96c2af8a
https://doi.org/10.1016/s1359-6446(01)01808-6

Zobrazit plný text záznamu

A conditional U5 snRNA mutation affecting pre-mRNA splicing and nuclear pre-mRNA retention identifies SSD1/SRK1 as a general splicing mutant suppressor

Autor: Bertrand Séraphin, B. G. Mattias Luukkonen

Publikováno v: Nucleic Acids Research. 27:3455-3465

A combination of point mutations disrupting both stem 1 and stem 2 of U5 snRNA (U5AI) was found to confer a thermosensitive phenotype in vivo. In a strain expressing U5AI, pre-mRNA splicing was blocked before the first step through an inability of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368ff162bb78e6a01a93e84a3fed2792
https://doi.org/10.1093/nar/27.17.3455

Zobrazit plný text záznamu

The role of branchpoint-3' splice site spacing and interaction between intron terminal nucleotides in 3' splice site selection in Saccharomyces cerevisiae

Autor: B. G. Mattias Luukkonen, Bertrand Séraphin

Publikováno v: The EMBO Journal. 16:779-792

A conserved 3' splice site YAG is essential for the second step of pre-mRNA splicing but no trans-acting factor recognizing this sequence has been found. A direct, non-Watson-Crick interaction between the intron terminal nucleotides was suggested to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb09a871df2301a9cc34540f6628872
https://doi.org/10.1093/emboj/16.4.779

Zobrazit plný text záznamu

New constructs and strategies for efficient PCR-based gene manipulations in yeast

Autor: Bertrand Séraphin, B. G. Mattias Luukkonen, Stefanie Kandels-Lewis, Oscar Puig, Elisabeth Bragado-Nilsson, Berthold Rutz

Publikováno v: Publons
Europe PubMed Central

Gene disruption and tagging can be achieved by homologous recombination in the yeast genome. Several PCR-based methods have been described towards this end. However these strategies are often limited in their applications and/or their efficiencies an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc00616c584f3fbd45ea1595de1f58ec
https://publons.com/publon/50621880/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání