Výsledky vyhledávání - "B. G. Elferink"

Identification of citrullinated vimentin peptides as T cell epitopes in HLAâDR4âpositive patients with rheumatoid arthritis

Autor: René R. P. de Vries, Hanane El Bannoudi, Anouk L. Feitsma, Andreea Ioan-Facsinay, Tom W J Huizinga, Kees L. M. C. Franken, Ellen I. H. van der Voort, B. G. Elferink, Jan W. Drijfhout, René E. M. Toes

Publikováno v: Arthritis & Rheumatism
Arthritis and Rheumatism, 62(1), 117-125
Arthritis and Rheumatism

Objective. Antibodies directed against citrullinated proteins (ACPAs) are highly specific for rheumatoid arthritis (RA). The production of ACPAs is most likely dependent on the presence of T cells, since ACPAs undergo isotype switching and are associ

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Activated Synovial T Cell Clones from a Patient with Rheumatoid Arthritis Induce Proliferation of Autologous Peripheral Blood-Derived T Cells

Autor: R. R. P. De Vries, B. G. Elferink, A. Leow, J. M. Van Laar, M. R. Daha, André M. M. Miltenburg, F. C. Breedveld, M. J. A. Verdonk

Publikováno v: Cellular Immunology. 146:71-79

In order to investigate cellular interactions involved in the development of human autoimmune disease, a synovial fluid-derived T cell clone reactive with mycobacterial antigens, termed k38, was employed as a stimulus for autologous peripheral blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1a199eb1d08b1d2cd6d8f5b86699fd
https://doi.org/10.1006/cimm.1993.1007

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Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

Autor: Franca C. Hartgers, Jolanda H. M. van Bilsen, A Bakker, B. G. Elferink, René E. M. Toes, Tom W J Huizinga, Mary E. Morgan, Marco W. Schilham, Tom H. M. Ottenhoff, Linda van der Zanden, Bianca Heemskerk, René R. P. de Vries

Publikováno v: Human Immunology, 66, 1, pp. 13-20
Human Immunology, 66, 13-20

Contains fulltext : 48463.pdf (Publisher’s version ) (Closed access) Expression of the transcription factor Foxp3 (forkhead box P3) has been implicated as a key element for CD25(+) T regulatory cell function in mice. However, literature over simila

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https://hdl.handle.net/2066/48463

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The biologic importance of conserved major histocompatibility complex class II motifs in primates

Autor: Annemieke Geluk, B. G. Elferink, R. R. P. De Vries, Nel Otting, R. E. Bontrop, Tom H. M. Ottenhoff, K. E. Van Meijgaarden, Bastiaan L. Slierendregt

Publikováno v: Human immunology. 38(3)

Phylogenetic comparisons of polymorphic second-exon sequences of MHC class II DRB genes showed that equivalents of the HLA-DRB1*03 alleles are present in various nonhuman primate species such as chimpanzees, gorillas, and rhesus macaques. These allel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9431765ad72bc4ede7c5f073f82ebd73
https://pubmed.ncbi.nlm.nih.gov/8106278

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Identification of citrullinated vimentin peptides as T cell epitopes in HLA-DR4 positive RA patients

Autor: Hanane El Bannoudi, Andreea Ioan-Facsinay, R. R. P. De Vries, Anouk L. Feitsma, J. W. Drijfhout, R.E.M. Toes, Kees L. M. C. Franken, E.I.H. van der Voort, T.W.J. Huizinga, B. G. Elferink

Publikováno v: Annals of the Rheumatic Diseases. 69:A74-A74

Antibodies directed against citrullinated proteins (ACPA) are highly specific for rheumatoid arthritis (RA). The production of ACPA is most likely dependent on the presence of T cells as ACPA have undergone isotype switching and associate with the sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0db07737cf9cf60072a7f09a8bdc8be6
https://doi.org/10.1136/ard.2010.129668x

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Role of HLA Class II Products in Proliferative T-Lymphocyte Responses to PPD

Autor: B. G. Elferink, W. Van Eden, Jo Hermans, R. R. P. De Vries, J.J. van Rood

Publikováno v: Scandinavian Journal of Immunology. 20:503-510

HLA class II determinants were analysed for their role in monocyte-T-cell interactions in the proliferative response to purified protein derivative (PPD). Allogeneic cell combinations of monocytes and T cells were tested with a range of suboptimal PP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d711a66a300f03c2d87783f60f3b0477
https://doi.org/10.1111/j.1365-3083.1984.tb01032.x

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HLA Class-II-restricted Mycobacterium lepraereactive T-Cell Clones from Leprosy Patients Established with a Minimal Requirement for Autologous Mononuclear Cells

Autor: J. B. A. G. HAANEN, T. H. M. OTTENHOFF, A. VOORDOUW, B. G. ELFERINK, P. R. KLATSER, H. SPITS, R. R. P. VRIES

Publikováno v: Scandinavian journal of immunology, 23(1), 101-108. Wiley-Blackwell

This report describes an effective method for the cloning of Mycobacterium leprae-reactive T lymphocytes with Epstein-Barr-virus transformed autologous B cells as antigen-presenting cells. The two advantages of this method are that it drastically red

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https://doi.org/10.1111/j.1365-3083.1986.tb01947.x

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Primary sensitisation and restimulation of human lymphocytes with soluble antigen in vitro

Autor: B G Elferink, E J Hensen

Publikováno v: Nature. 277:223-225

RESEARCH with human lymphocytes is restricted by ethical constraints on sensitising individuals in vivo before in vitro experiments. In humans specific restimulation of proliferative responses was first shown using allogeneic lymphocytes as antigen a

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https://doi.org/10.1038/277223a0

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Evidence for Intra HLA-DR and -DQ Subregion Crossing Over Events

Autor: Marius J. Giphart, M. G. J. Tilanus, Nel Otting, R. R. P. de Vries, B. G. Elferink, R. E. Bontrop

Publikováno v: Immunobiology of HLA ISBN: 9783662389805

The HLA-DR and -DQ region of 47 homozygous typing cell lines were analyzed by a variety of techniques such as restriction fragment length polymorphism analysis, gel electrophoretic screening of the gene products, and in some cases, by testing MHC cla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f63759d09ad0967dd7742d50907a90e
https://doi.org/10.1007/978-3-662-39946-0_111

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