Zobrazeno 1 - 10 of 13 pro vyhledávání: '"B. F. Kilpatrick"'
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2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as nonbenzodiazepine anticonvulsants and anxiolytics
Autor: L. M. Moses, B. F. Kilpatrick, Taylor Cr, Lo Ys, Johnson Dn, W. B. Kinnier, Tomczuk Be, D. B. Sutherland
Publikováno v: Journal of Medicinal Chemistry. 34:2993-3006
A series of 2-phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides were designed and synthesized as non-benzodiazepine anxiolytics based on a molecular disconnection of a typical 1,4-benzodiazepine (BZD). A number of these compounds showed submicromolar pot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60c4b70dbe8d2db1a4694a46ed1d5771
https://doi.org/10.1021/jm00114a007
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3
Characterization of the recombinant IKK1/IKK2 heterodimer. Mechanisms regulating kinase activity
Autor: Q K, Huynh, H, Boddupalli, S A, Rouw, C M, Koboldt, T, Hall, C, Sommers, S D, Hauser, J L, Pierce, R G, Combs, B A, Reitz, J A, Diaz-Collier, R A, Weinberg, B L, Hood, B F, Kilpatrick, C S, Tripp
Publikováno v: The Journal of biological chemistry. 275(34)
Nuclear factor kappa B (NF-kappaB) is a ubiquitous, inducible transcription factor that regulates the initiation and progression of immune and inflammatory stress responses. NF-kappaB activation depends on phosphorylation and degradation of its inhib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19d8b6752817687896aba224ea255448
https://pubmed.ncbi.nlm.nih.gov/10823818
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4
AHR-14310C: a potent, long-acting, nonsedating H1-antihistamine that prevents antigen-induced mucus formation in sensitive rats
Autor: J C, Nolan, M H, Foxwell, L L, Whitman, J M, Yanni, D A, Walsh, B F, Kilpatrick, D N, Johnson, A G, Proakis
Publikováno v: The Journal of pharmacology and experimental therapeutics. 253(3)
AHR-14310C(5-[2-[4-[bis(4-fluorophenyl)hydroxymethyl- 1-piperidinyl]ethyl]-3-methyl]-2-oxazolidinone ethanedioate, hydrochloride salt) displays potent and long-acting antihistaminic activity in guinea pigs and in dog and guinea pig models of immediat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9774167ea539a6d79712944d92d1f2fc
https://pubmed.ncbi.nlm.nih.gov/1972750
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5
Use of procainamide gels in the purification of human and horse serum cholinesterases
Autor: A L Chasson, B F Kilpatrick, A R Main, J S Ralston
Publikováno v: Biochemical Journal. 211:243-250
Two large-scale methods based primarily on the use of procainamide-Sepharose gels were developed for the purification of horse and human serum non-specific cholinesterases. With method I, the procainamide-Sepharose 4B gel was used in the first step t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b6762aa30b8eba830601ab8668b34a
https://doi.org/10.1042/bj2110243
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7
Dopamine receptor of the porcine anterior pituitary gland. Solubilization and characterization
Autor: B F, Kilpatrick, M G, Caron
Publikováno v: Biochemical pharmacology. 33(12)
In the anterior pituitary gland, dopamine controls the release of prolactin from the mammotrophs. The dopamine receptors in the porcine gland have been shown to exist in two different affinity states of equal proportion, one bearing high affinity for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a3143c7419f4de1ced850c1a27e5323
https://pubmed.ncbi.nlm.nih.gov/6547344
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