Continuing Education Workshops in Bioinformatics Positively Impact Research and Careers.

Autor: Michelle D Brazas, B F Francis Ouellette

Publikováno v: PLoS Computational Biology, Vol 12, Iss 6, p e1004916 (2016)

Bioinformatics.ca has been hosting continuing education programs in introductory and advanced bioinformatics topics in Canada since 1999 and has trained more than 2,000 participants to date. These workshops have been adapted over the years to keep pa

Externí odkaz: https://doaj.org/article/a9cade0d454f4f7485975343ae939b33

Transcriptomics data availability and reusability in the transition from microarray to next-generation sequencing

Autor: Roger E. Bumgarner, Giuseppe Jurman, Michael R. Reich, Christian J. Stoeckert, Ronald C. Taylor, Liliana Greger, Cesare Furlanello, Eleanor Williams, Stephen Chervitz Trutane, B. F. Francis Ouellette, Alvis Brazma, Marco Chierici, Brian T. Wilhelm, Mitra Barzine, Michael Miller, Jennifer B. Weller, Gabriella Rustici, John Quackenbush, Neil Winegarden

Over the last two decades, molecular biology has been changed by the introduction of high-throughput technologies. Data sharing requirements have prompted the establishment of persistent data archives. A standardized approach for recording and managi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cec16305ef94bdab41c074f9e19e5c34
https://doi.org/10.1101/2020.12.31.425022

Genomic basis for RNA alterations in cancer

Autor: Natalie R. Davidson, Matthew Meyerson, Lara Urban, Helena Kilpinen, Katherine A. Hoadley, Jan O. Korbel, Huanming Yang, Fan Zhang, Liliana Greger, Reiner Siebert, Jonathan Göke, Serap Erkek, Chad J. Creighton, Patrick Tan, Oliver Stegle, Marc D. Perry, Hong Su, Julia Markowski, Kui Wu, Angela N. Brooks, Dongbing Liu, Gunnar Rätsch, Qian Xiang, Christina K. Yung, Yong Hou, Nuno A. Fonseca, Shida Zhu, Chandra Sekhar Pedamallu, Tannistha Nandi, B. F. Francis Ouellette, Siliang Li, Yao He, Zemin Zhang, Junjun Zhang, André Kahles, Peter Bailey, Claudia Calabrese, Philip Awadalla, Kjong-Van Lehmann, Alvis Brazma, Roland F. Schwarz, Stefan G. Stark, Sebastian M. Waszak, Maximillian G. Marin, Yuichi Shiraishi, Cameron M. Soulette, Qiang Pan-Hammarström, Deniz Demircioğlu, Matthew R. Huska, Fenglin Liu

Publikováno v: Nature, 578 (7793)
PCAWG Transcriptome Core Group, PCAWG Transcriptome Working Group & PCAWG Consortium 2020, ' Genomic basis for RNA alterations in cancer ', Nature, vol. 578, no. 7793, pp. 129-136 . https://doi.org/10.1038/s41586-020-1970-0
Nature, 578, 7793, pp. 129-136
Nature, 578, 129-136
Nature

Transcript alterations often result from somatic changes in cancer genomes1. Various forms of RNA alterations have been described in cancer, including overexpression2, altered splicing3 and gene fusions4; however, it is difficult to attribute these t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f198f7d05a25ecd90691339023e487f
https://hdl.handle.net/20.500.11850/399330

ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteins

Autor: Marta Paczkowska, Michal Krassowski, Amélie Fradet-Turcotte, B. F. Francis Ouellette, Irakli Dzneladze, Tina Huang, Joseph Tadashi Yamada, Jüri Reimand, Kim Cullion

Publikováno v: Nucleic Acids Research

Interpretation of genetic variation is required for understanding genotype-phenotype associations, mechanisms of inherited disease, and drivers of cancer. Millions of single nucleotide variants (SNVs) in human genomes are known and thousands are asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa6f4dd122c91208e98386111475843
https://doi.org/10.1093/nar/gkx973

The International Cancer Genome Consortium's evolving data-protection policies

Autor: Pilar Nicolás, Don Chalmers, B. F. Francis Ouellette, Stephanie O.M. Dyke, Edward S. Dove, Kazuto Kato, Yann Joly, Djims Milius, Laura Lyman Rodriguez, Nikolajs Zeps, Brad Ozenberger

Publikováno v: Nature Biotechnology. 32:519-523

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed481e768c7d6e82baddafa8808e5a3
https://doi.org/10.1038/nbt.2926