Zobrazeno 1 - 7 of 7 pro vyhledávání: '"B. F. Cravatt"'
1
Diacylglycerol lipase β inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain
Autor: J L, Wilkerson, S, Ghosh, D, Bagdas, B L, Mason, M S, Crowe, K L, Hsu, L E, Wise, S G, Kinsey, M I, Damaj, B F, Cravatt, A H, Lichtman
Publikováno v: British journal of pharmacology. 173(10)
Inhibition of diacylglycerol lipase (DGL)β prevents LPS-induced pro-inflammatory responses in mouse peritoneal macrophages. Thus, the present study tested whether DGLβ inhibition reverses allodynic responses of mice in the LPS model of inflammatory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eabd6e23af95901089be0f48a43cd11b
https://pubmed.ncbi.nlm.nih.gov/26915789
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2
Akademický článek
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3
COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation
Autor: A, Straiker, J, Wager-Miller, S S, Hu, J L, Blankman, B F, Cravatt, K, Mackie
Publikováno v: British journal of pharmacology. 164(6)
Depolarization-induced suppression of inhibition (DSI) and excitation (DSE) are two forms of cannabinoid CB(1) receptor-mediated inhibition of synaptic transmission, whose durations are regulated by endocannabinoid (eCB) degradation. We have recently
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ef283582998a1256f8b37c63fbbbc21c
https://pubmed.ncbi.nlm.nih.gov/21564090
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5
Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides
Autor: M P, Patricelli, B F, Cravatt
Publikováno v: Vitamins and hormones. 62
Fatty acid amides (FAAs) represent a growing family of biologically active lipids implicated in a diverse range of cellular and physiological processes. At present, two general types of fatty acid amides, the N-acylethanolamines (NAEs) and the fatty
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c1ca84d8242b284ce0a9640389130cf
https://pubmed.ncbi.nlm.nih.gov/11345902
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6
Oleamide: an endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules
Autor: D L, Boger, S J, Henriksen, B F, Cravatt
Publikováno v: Current pharmaceutical design. 4(4)
Oleamide is an endogenous fatty acid primary amide that accumulates in the cerebrospinal fluid under conditions of sleep deprivation and induces physiological sleep in animals. A review covering its discovery, its implications, and the emerging biolo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d46c016a98c2294f3ba7672e151313ab
https://pubmed.ncbi.nlm.nih.gov/10197045
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7
Fatty acid amide hydrolase, the degradative enzyme for anandamide and oleamide, has selective distribution in neurons within the rat central nervous system
Autor: E A, Thomas, B F, Cravatt, P E, Danielson, N B, Gilula, J G, Sutcliffe
Publikováno v: Journal of neuroscience research. 50(6)
Fatty acid amide hydrolase (FAAH) is a membrane-bound enzyme activity that degrades neuromodulatory fatty acid amides, including oleamide and anandamide. A single 2.5-kb FAAH mRNA is distributed throughout the rat CNS and accumulates progressively be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4355fd3d26cc3d0a2785aba21392bb8
https://pubmed.ncbi.nlm.nih.gov/9452020
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