Výsledky vyhledávání - "B. El Hassouni"

Akademický článek

Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma

Autor: T. Y. S. Le Large, M. F. Bijlsma, B. El Hassouni, G. Mantini, T. Lagerweij, A. A. Henneman, N. Funel, B. Kok, T. V. Pham, R. de Haas, L. Morelli, J. C. Knol, S. R. Piersma, G. Kazemier, H. W. M. van Laarhoven, E. Giovannetti, C. R. Jimenez

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease, with minimal therapeutic options. Aberrant tyrosine kinase activity influences tumor growth and is regulated by phosphorylation. We investigated phosphorylated kina

Externí odkaz: https://doaj.org/article/0ff8e86f001a413e86274af4e9721346

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Direct torque control improvement of a variable speed DFIG based on a fuzzy inference system

Autor: Wiam Ayrir, Ali Haddi, M. Ourahou, B. El Hassouni

Publikováno v: Mathematics and Computers in Simulation. 167:308-324

In this paper, a fuzzy direct torque control (DTC) for a variable speed doubly fed induction generator (DFIG) based wind turbine is investigated. The DTC has been widely applied to doubly fed induction machines in recent years due to the high perform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e6cb001ef757d612158b377e87d7030
https://doi.org/10.1016/j.matcom.2018.05.014

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Review on smart grid control and reliability in presence of renewable energies: Challenges and prospects

Autor: Ali Haddi, Wiam Ayrir, M. Ourahou, B. El Hassouni

Publikováno v: Mathematics and Computers in Simulation. 167:19-31

This paper deals with smart grid concept and its reliability in presence of renewable energies. Around the globe an adjustment of electric energy is required to limit CO2 gas emission, preserve the greenhouse, limit pollution, fight climate change an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a25c070078ddb6224ab816b971b7b39d
https://doi.org/10.1016/j.matcom.2018.11.009

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Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma

Autor: Bart Kok, Tonny Lagerweij, Jaco C. Knol, Giulia Mantini, Geert Kazemier, T.Y.S. Le Large, Sander R. Piersma, B. El Hassouni, Maarten F. Bijlsma, Elisa Giovannetti, Alexander A. Henneman, Connie R. Jimenez, H.W.M. van Laarhoven, Luca Morelli, Niccola Funel, R. R. de Haas, Thang V. Pham

Publikováno v: Journal of Experimental & Clinical Cancer Research : CR
le Large, T Y S, Bijlsma, M F, el Hassouni, B, Mantini, G, Lagerweij, T, Henneman, A A, Funel, N, Kok, B, Pham, T V, de Haas, R, Morelli, L, Knol, J C, Piersma, S R, Kazemier, G, van Laarhoven, H W M, Giovannetti, E & Jimenez, C R 2021, ' Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma ', JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, vol. 40, no. 1, 91 . https://doi.org/10.1186/s13046-021-01892-z
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 40(1):91. BioMed Central
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Journal of experimental & clinical cancer research, 40(1):91. BioMed Central

Background Pancreatic ductal adenocarcinoma (PDAC) is a very lethal disease, with minimal therapeutic options. Aberrant tyrosine kinase activity influences tumor growth and is regulated by phosphorylation. We investigated phosphorylated kinases as ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8214a63d52784a518e8ca3893d4ce0e7
http://www.scopus.com/inward/record.url?scp=85102552220&partnerID=8YFLogxK

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Additional file 1 of Focal adhesion kinase inhibition synergizes with nab-paclitaxel to target pancreatic ductal adenocarcinoma

Autor: T. Y. S. Le Large, M. F. Bijlsma, B. El Hassouni, G. Mantini, T. Lagerweij, A. A. Henneman, N. Funel, B. Kok, T. V. Pham, R. De Haas, L. Morelli, J. C. Knol, S. R. Piersma, G. Kazemier, H. W. M. Van Laarhoven, Giovannetti, E., C. R. Jimenez

Additional file 1: Supplemental Fig. 1. General description of phosphotyrosine-enriched analysis. a. Pearson correlation of technical replicates showed good correlation, replicate 1 represents a technical replicate in one dataset, while replicate 2 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6338437cb2821f577f139910f9cd10a7

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Akademický článek

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PO-042 Targeting hypoxic pancreatic cancer cells with glucose conjugated lactate dehydrogenase inhibitor NHI-Glc-2

Autor: Paul J. Hergenrother, Giulia Mantini, B. El Hassouni, Hyang Yeon Lee, Filippo Minutolo, Rocco Sciarrillo, Niccola Funel, G.J. Peters, Elisa Giovannetti

Publikováno v: ESMO Open. 3:A243-A244

Introduction Pancreatic ductal adenocarcinoma (PDAC) is an abysmal disease with a 5 year survival rate of merely 8%. The tumour microenvironment is one of the factors contributing to PDAC chemoresistance. More specifically, the hypoxic tumour cores a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::745706188b3640c27e81d69b693a3678
https://doi.org/10.1136/esmoopen-2018-eacr25.575

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PO-278 Assessment of the influence of stellate cells on primary pancreatic cancer cell growth and drug resistance in a spheroid model: MET inhibitors to the rescue

Autor: PP Che, Elisa Giovannetti, B. El Hassouni, C Stefano, G.J. Peters, M Buijs, Luciano Saso, Matthias Löhr, Omidreza Firuzi, Rainer Heuchel

Publikováno v: ESMO Open. 3:A336

Introduction Pancreatic ductal adenocarcinoma has one of the lowest 5 year survival rates among all cancers and it is going to be the 2nd leading cause of cancer death in 2030. Drug resistance and early metastasis are among the main causes of this di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7806e2e255bcc015e5fd57586e94bf71
https://doi.org/10.1136/esmoopen-2018-eacr25.792

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