Výsledky vyhledávání - "B. E. Wenzel"

Thyroid-Stimulating Hormone, a Novel, Locally Produced Modulator of Human Epidermal Functions, Is Regulated by Thyrotropin-Releasing Hormone and Thyroid Hormones

Autor: Enikő Bodó, B. E. Wenzel, Tamás Bíró, Arno Kromminga, Ralf Paus, Burkhard Poeggeler, K.C. Meyer, Stephan Tiede, Erzsébet Gáspár, Nina van Beek, Benedikt Kany, Yuval Ramot, Jana Knüver

Publikováno v: Endocrinology. 151:1633-1642

Several elements of the hypothalamic-pituitary-thyroid axis (HPT) reportedly are transcribed by human skin cell populations, and human hair follicles express functional receptors for TSH. Therefore, we asked whether the epidermis of normal human skin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d327fe479b6e94bbc4df7ea27e9e125
https://doi.org/10.1210/en.2009-0306

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Molecular analysis of antigen receptor variable region repertoires in T lymphocytes infiltrating the intrathyroidal and extrathyroidal manifestations in patients with Graves' disease*

Autor: Armin E. Heufelder, Rebecca S. Bahn, James A. Garrity, B. E. Wenzel, H.-D. Schworm

Publikováno v: Experimental and Clinical Endocrinology & Diabetes. 104:84-87

To determine whether T cells infiltrating thyroid, orbital and pretibial tissue of patients with Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD) represent a primary immune response that is directed against certain antigenic determinants sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d3a0e06310bf58635d2caa06fb116a
https://doi.org/10.1055/s-0029-1211709

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New frontiers in human hair follicle (neuro-)endocrinology

Autor: Sybille Hasse, Wolfgang Jelkmann, M. Laugsch, A. Kromminga, B. E. Wenzel, Ralf Paus, Enikő Bodó

Publikováno v: Experimental Dermatology. 15:643-648

Recently, we have shown that normal human scalp hair follicles in anagen VI (a) synthesize CRH, ACTH, alpha-MSH and cortisol and display a fully functional equivalent of the hypothalamus–pituitary–adrenal axis (Ito et al. FASEB J 2005) (b) synthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0a46119c7b939a48248a2673ef37ba6
https://doi.org/10.1111/j.1600-0625.2006.00439h.x

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Reduced radioiodine uptake at increased iodine intake and 131I-induced release of 'cold' iodine stored in the thyroid

Autor: M. Baehre, E. Richter, B. E. Wenzel, M. Seyfarth, A. Haase, B. Meller

Publikováno v: Nuklearmedizin. 44:137-142

Summary Aim: The extent of urinary iodine excretion (UIE) provides information about iodine supply and release. In the present study we investigated correlations between UIE and radioiodine uptake (RIU) as well as effects of radioiodine therapy on UI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4870881446270d20f2ef45212fc72bad
https://doi.org/10.1055/s-0038-1625756

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In old age the majority of thyroid peroxidase autoantibodies are directed to a single TPO domain irrespective of thyroid function and iodine intake

Autor: B. E. Wenzel, Orsolya Dohán, Danuta Pastuszko, Barbara Czarnocka, István Szabolcs, Jan Podoba, Joachim Feldkamp

Publikováno v: Clinical Endocrinology. 48:803-808

OBJECTIVE We have examined (1) which epitopes on thyroid peroxidase (TPO) are recognized by TPO autoantibodies (TPO-Aab) in old age and to what extent? (2) Does the TPO-Aab pattern differ in euthyroid and hypothyroid elderly subjects or does it depen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0004468463d1b44e6dec7dcdb1c2ef6
https://doi.org/10.1046/j.1365-2265.1998.00467.x

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Thyrotropin powers human mitochondria

Autor: Matthias Klinger, Enikő Bodó, Ralf Paus, Burkhard Poeggeler, Jana Knuever, Rudolf J. Wiesner, Erzsébet Gáspár, B. E. Wenzel, Tamás Bíró

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(5)

Here we demonstrate that the neuropeptide hormone thyrotropin (TSH), which controls thyroid hormone production, exerts a major nonclassical function in mitochondrial biology. Based on transcriptional, ultrastructural, immunohistochemical, and biochem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ecfa66888793f95f1f2e5345d7d835
https://pubmed.ncbi.nlm.nih.gov/20075194

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In situ hybridization of the mRNA for interferon-γ, interferon-αE, interferon-β, interleukin-1β and interleukin-6 and characterization of infiltrating cells in thyroid tissues

Autor: Holger Kirchner, Lothar Rink, Andrea Kruse, Inge Rutenfranz, B. E. Wenzel, Hans Arnholdt

Publikováno v: Journal of Immunological Methods. 148:233-242

Cytokine mRNA production in the thyroid tissues of patients with various thyroid diseases was analysed by in situ hybridization. In addition, infiltrating leukocytes were characterized by immunohistologic studies using the alkaline phosphatase anti-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4224a431142b3c87f98dafa3e040b9
https://doi.org/10.1016/0022-1759(92)90177-u

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Thyrotropin releasing hormone (TRH): a new player in human hair-growth control

Autor: Enikő Bodó, Erzsébet Gáspár, Arno Kromminga, Ralf Paus, Wolfgang Funk, B. E. Wenzel, Yuval Ramot, Celine Hardenbicker

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(2)

Thyrotropin-releasing hormone (TRH) is the most proximal component of the hypothalamic-pituitary-thyroid axis that regulates thyroid hormone synthesis. Since transcripts for members of this axis were detected in cultured normal human skin cells and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9576b00071f82eadac17eb0c3723ad2
https://pubmed.ncbi.nlm.nih.gov/19825978

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Thyroid hormones directly alter human hair follicle functions: anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation

Autor: Arno Kromminga, Ralf Paus, K.C. Meyer, Nina van Beek, Erzsébet Gáspár, Enikö Bodó, Andrzej Slominski, B. E. Wenzel, Michal A. Zmijewski

Publikováno v: The Journal of clinical endocrinology and metabolism. 93(11)

Context: Both insufficient and excess levels of thyroid hormones (T3 and T4) can result in altered hair/skin structure and function (e.g. effluvium). However, it is still unclear whether T3 and T4 exert any direct effects on human hair follicles (HFs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfeda373ca45997dde25ce4c6991eddf
https://pubmed.ncbi.nlm.nih.gov/18728176

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