Zobrazeno 1 - 10
of 30
pro vyhledávání: '"B. E. Lehnert"'
Publikováno v:
Experimental Lung Research. 18:435-446
Pulmonary macrophages (PM) exist in two general anatomical compartments in the lower respiratory tract: the alveolar space (alveolar macrophages, AM) and the interstitium (interstitial macrophages, IM). We determined the relative contribution that ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aecb1aa4c2398079ebc6aae8f9dd5e89
https://doi.org/10.3109/01902149209064338
https://doi.org/10.3109/01902149209064338
Autor:
D. M. Stavert, B. E. Lehnert
Publikováno v:
Inhalation Toxicology. 2:53-67
This investigation was undertaken in order to examine the pulmonary inflammatory response to nitric oxide (NO) relative to that of nitrogen dioxide (NO2) when breathed at high concentrations for short durations. Croups of adult, male Fischer 344 rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a10475f66696ad581a480fbf6c1995f
https://doi.org/10.3109/08958379009145245
https://doi.org/10.3109/08958379009145245
Publikováno v:
Biomedical Optical Spectroscopy and Diagnostics.
We demonstrate a high speed method to analyze the impact of self-quenching on fluorescence lifetimes in individual cells by phase-sensitive flow cytometry, using a model system consisting of FITC (fluorescein isothiocyanate) labeled antimouse Thy 1.2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::142f35e46cc2dc4f9132e7e561a904bb
https://doi.org/10.1364/bosd.1996.ca1
https://doi.org/10.1364/bosd.1996.ca1
Publikováno v:
Cancer research. 60(5)
Increases in cell proliferation are widely viewed as being of importance in carcinogenesis. We report that exposure of normal human lung fibroblasts to a low dose of alpha particles like those emitted by radon/radon progeny stimulates their prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ee36932c97e5e46f186c12f6fb51bfc
https://pubmed.ncbi.nlm.nih.gov/10728689
https://pubmed.ncbi.nlm.nih.gov/10728689
Publikováno v:
Cytometry. 39(1)
Spectral interference (overlap) from phagocytosed green-yellow (GY) microspheres in the flow cytometric, red fluorescence emission measurement channel causes errors in quantifying damaged/dead alveolar macrophages by uptake of propidium iodide.Partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a0ac98c1b10acb58fe3706a5df51050
https://pubmed.ncbi.nlm.nih.gov/10655562
https://pubmed.ncbi.nlm.nih.gov/10655562
Publikováno v:
Cytometry. 37(4)
The primary source of interference in immunofluorescence measurements by flow cytometry is background autofluorescence.Using human lung fibroblasts (HLFs) as an autofluorescent cell model, unfixed HLFs and HLFs fixed in methanol, ethanol, formaldehyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82dc95d4a7571fb4736eec4df7300b0e
https://pubmed.ncbi.nlm.nih.gov/10547612
https://pubmed.ncbi.nlm.nih.gov/10547612
Publikováno v:
Radiation research. 152(1)
The pulmonary microenvironment is a primary target for alpha particles like those emitted by inhaled radon and its progeny. While exposure to alpha particles has recently been associated with the generation of extracellular and intracellular reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09c26d19cf04ccb8569b216281f4a052
https://pubmed.ncbi.nlm.nih.gov/10381841
https://pubmed.ncbi.nlm.nih.gov/10381841
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 712(1-2)
The protein kinase inhibitor staurosporine (Stsp) has been used extensively to study physiological functions, biochemical mechanisms, and cancer therapy. Using an HPLC assay for Stsp developed in our laboratory, we find that only 0.7% of Stsp remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::208ffe12be00c87f6e6334fb9e1ada98
https://pubmed.ncbi.nlm.nih.gov/9698244
https://pubmed.ncbi.nlm.nih.gov/9698244
Publikováno v:
Cancer research. 57(18)
The mechanism(s) by which high-linear energy transfer a particles, like those emitted by inhaled radon and radon daughters, cause lung cancer has not been elucidated. Conceivably, DNA damage that is induced by a particles may be mediated by the metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6f4d09276bc6659f93fc3af37c95f43
https://pubmed.ncbi.nlm.nih.gov/9307280
https://pubmed.ncbi.nlm.nih.gov/9307280
Autor:
D M, Gadbois, B E, Lehnert
Publikováno v:
Cancer research. 57(15)
Epithelial cells along the conducting airways can be more or less continuously exposed to DNA-damaging agents, which should limit their proliferation by inducing cell cycle checkpoints. Yet, paradoxically, airway epithelial cells frequently show a hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f8b4d6f5084b9b84263ec692121199e
https://pubmed.ncbi.nlm.nih.gov/9242446
https://pubmed.ncbi.nlm.nih.gov/9242446